ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	56/592	152/7206	1.61356846892e-23
ko05033	Nicotine addiction	34/592	56/7206	1.95513063442e-23
ko04080	Neuroactive ligand-receptor interaction	91/592	423/7206	9.76221499325e-19
ko04728	Dopaminergic synapse	52/592	185/7206	4.99207246357e-16
ko04727	GABAergic synapse	37/592	110/7206	2.00864797002e-14
ko05032	Morphine addiction	37/592	110/7206	2.00864797002e-14
ko04723	Retrograde endocannabinoid signaling	46/592	175/7206	3.95063678085e-13
ko04713	Circadian entrainment	39/592	136/7206	1.32606981957e-12
ko04721	Synaptic vesicle cycle	29/592	80/7206	1.64163960337e-12
ko04911	Insulin secretion	35/592	117/7206	5.08636109478e-12
ko04024	cAMP signaling pathway	58/592	279/7206	1.52908391084e-11
ko04725	Cholinergic synapse	40/592	160/7206	7.79560188618e-11
ko04514	Cell adhesion molecules (CAMs)	34/592	130/7206	5.88916608518e-10
ko04261	Adrenergic signaling in cardiomyocytes	44/592	205/7206	1.74554008983e-09
ko05030	Cocaine addiction	23/592	73/7206	8.03930403808e-09
ko05031	Amphetamine addiction	25/592	91/7206	4.00258481218e-08
ko04010	MAPK signaling pathway	53/592	321/7206	6.24500416717e-07
ko04921	Oxytocin signaling pathway	39/592	209/7206	1.01693123673e-06
ko04720	Long-term potentiation	23/592	99/7206	3.4971591395e-06
ko04020	Calcium signaling pathway	43/592	265/7206	1.11664864258e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/592	79/7206	1.45314111175e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/592	74/7206	2.06339219265e-05
ko05203	Viral carcinogenesis	6/592	277/7206	2.80378627875e-05
ko04360	Axon guidance	38/592	233/7206	4.44266289675e-05
ko04742	Taste transduction	15/592	61/7206	8.76704834695e-05
ko03040	Spliceosome	1/592	145/7206	9.05691815163e-05
ko04060	Cytokine-cytokine receptor interaction	3/592	191/7206	0.000136987185275
ko04970	Salivary secretion	19/592	95/7206	0.000212621210439
ko04972	Pancreatic secretion	21/592	111/7206	0.000296317144125
ko04726	Serotonergic synapse	24/592	137/7206	0.000380574320643
ko04730	Long-term depression	16/592	78/7206	0.000491191184026
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/592	14/7206	0.000507335600679
ko04260	Cardiac muscle contraction	19/592	98/7206	0.000535439307694
ko05414	Dilated cardiomyopathy	20/592	112/7206	0.000760139960828
ko05164	Influenza A	3/592	167/7206	0.000834018893383
ko05168	Herpes simplex infection	4/592	182/7206	0.00092743665746
ko05410	Hypertrophic cardiomyopathy (HCM)	18/592	100/7206	0.00133319690441
ko00240	Pyrimidine metabolism	1/592	110/7206	0.00136887792282
ko04120	Ubiquitin mediated proteolysis	2/592	138/7206	0.00138321518683
ko04022	cGMP-PKG signaling pathway	31/592	216/7206	0.00222941732304
ko05322	Systemic lupus erythematosus	3/592	151/7206	0.00233250272818
ko04110	Cell cycle	3/592	145/7206	0.00325142670158
ko05205	Proteoglycans in cancer	10/592	271/7206	0.00327591425669
ko04072	Phospholipase D signaling pathway	28/592	197/7206	0.00357679348314
ko03013	RNA transport	4/592	166/7206	0.00369140178934
ko05162	Measles	2/592	120/7206	0.00390777628356
ko04621	NOD-like receptor signaling pathway	4/592	157/7206	0.00491506316825
ko04925	Aldosterone synthesis and secretion	17/592	105/7206	0.0061797144815
ko05215	Prostate cancer	2/592	111/7206	0.00803988220904
ko04630	Jak-STAT signaling pathway	3/592	132/7206	0.00930455053233
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/592	182/7206	0.0128713208179
ko00515	Mannose type O-glycan biosynthesis	6/592	25/7206	0.0137374880088
ko04915	Estrogen signaling pathway	19/592	131/7206	0.0145678719442
ko04971	Gastric acid secretion	15/592	98/7206	0.0154481656002
ko04966	Collecting duct acid secretion	6/592	26/7206	0.0166521420151
ko04350	TGF-beta signaling pathway	2/592	103/7206	0.0167720528795
ko05169	Epstein-Barr virus infection	8/592	206/7206	0.0196580051105
ko04612	Antigen processing and presentation	1/592	77/7206	0.0197717118208
ko04144	Endocytosis	40/592	342/7206	0.020088956092
ko03008	Ribosome biogenesis in eukaryotes	1/592	79/7206	0.0205070450201
ko04068	FoxO signaling pathway	6/592	167/7206	0.0223730340817
ko00512	Mucin type O-glycan biosynthesis	6/592	29/7206	0.0278776326387
ko04141	Protein processing in endoplasmic reticulum	7/592	184/7206	0.0281981874706
ko04214	Apoptosis - fly	1/592	72/7206	0.0287043401115
ko04146	Peroxisome	2/592	89/7206	0.0322277847548
ko05110	Vibrio cholerae infection	10/592	63/7206	0.0358268867082
ko04218	Cellular senescence	7/592	177/7206	0.0364874654919
ko04740	Olfactory transduction	12/592	80/7206	0.0375411457491
ko04930	Type II diabetes mellitus	9/592	54/7206	0.0399040624639
ko04510	Focal adhesion	11/592	240/7206	0.0409178807182
ko05223	Non-small cell lung cancer	1/592	66/7206	0.0413129817569
ko03018	RNA degradation	2/592	84/7206	0.0453310439195
ko05161	Hepatitis B	7/592	173/7206	0.0480617174234
ko04540	Gap junction	17/592	128/7206	0.0487769533373