ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	189/1182	423/7206	9.81536719177e-46
ko04724	Glutamatergic synapse	83/1182	152/7206	1.18952115552e-27
ko05033	Nicotine addiction	45/1182	56/7206	5.36058426075e-26
ko04713	Circadian entrainment	69/1182	136/7206	9.70936542885e-21
ko05032	Morphine addiction	60/1182	110/7206	3.07416592135e-20
ko04020	Calcium signaling pathway	104/1182	265/7206	1.34475353677e-19
ko04728	Dopaminergic synapse	80/1182	185/7206	2.08930131164e-18
ko04727	GABAergic synapse	56/1182	110/7206	3.88374891542e-17
ko04721	Synaptic vesicle cycle	46/1182	80/7206	5.1743051235e-17
ko04725	Cholinergic synapse	69/1182	160/7206	5.956169618e-16
ko04024	cAMP signaling pathway	99/1182	279/7206	2.4064343815e-15
ko04723	Retrograde endocannabinoid signaling	69/1182	175/7206	1.49687111842e-13
ko04911	Insulin secretion	51/1182	117/7206	2.49396193222e-12
ko04921	Oxytocin signaling pathway	75/1182	209/7206	3.62047449556e-12
ko04726	Serotonergic synapse	56/1182	137/7206	5.10672836098e-12
ko05031	Amphetamine addiction	40/1182	91/7206	4.35833498097e-10
ko04742	Taste transduction	31/1182	61/7206	4.86320995676e-10
ko04970	Salivary secretion	41/1182	95/7206	5.23740654899e-10
ko04744	Phototransduction	22/1182	36/7206	1.65143741589e-09
ko04022	cGMP-PKG signaling pathway	71/1182	216/7206	1.71906424755e-09
ko03010	Ribosome	1/1182	129/7206	4.21876226416e-09
ko03040	Spliceosome	3/1182	145/7206	3.97753202477e-08
ko04720	Long-term potentiation	39/1182	99/7206	4.81324891697e-08
ko05322	Systemic lupus erythematosus	4/1182	151/7206	8.71507722303e-08
ko04261	Adrenergic signaling in cardiomyocytes	64/1182	205/7206	8.77500648434e-08
ko04971	Gastric acid secretion	37/1182	98/7206	2.72350054407e-07
ko05203	Viral carcinogenesis	17/1182	277/7206	3.16434899242e-07
ko04925	Aldosterone synthesis and secretion	39/1182	105/7206	3.2598077125e-07
ko05168	Herpes simplex infection	9/1182	182/7206	3.49108386399e-06
ko04070	Phosphatidylinositol signaling system	38/1182	112/7206	4.23024561658e-06
ko03013	RNA transport	8/1182	166/7206	6.17118599068e-06
ko05164	Influenza A	8/1182	167/7206	6.30017836056e-06
ko05030	Cocaine addiction	28/1182	73/7206	6.98676000053e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1182	74/7206	2.33112705594e-05
ko04110	Cell cycle	7/1182	145/7206	3.35462380755e-05
ko04730	Long-term depression	28/1182	78/7206	3.4734219129e-05
ko04745	Phototransduction - fly	17/1182	38/7206	3.6645406894e-05
ko04120	Ubiquitin mediated proteolysis	7/1182	138/7206	6.5172513268e-05
ko04966	Collecting duct acid secretion	13/1182	26/7206	7.38858461778e-05
ko04060	Cytokine-cytokine receptor interaction	13/1182	191/7206	9.74770262604e-05
ko05169	Epstein-Barr virus infection	15/1182	206/7206	0.000121243886405
ko04972	Pancreatic secretion	34/1182	111/7206	0.000151786443401
ko03008	Ribosome biogenesis in eukaryotes	2/1182	79/7206	0.00017230284423
ko04072	Phospholipase D signaling pathway	53/1182	197/7206	0.000180070162543
ko04710	Circadian rhythm	17/1182	43/7206	0.000236419798209
ko04141	Protein processing in endoplasmic reticulum	13/1182	184/7206	0.000245933389482
ko04621	NOD-like receptor signaling pathway	10/1182	157/7206	0.000273350349616
ko04371	Apelin signaling pathway	48/1182	177/7206	0.000278056897149
ko04740	Olfactory transduction	26/1182	80/7206	0.000355369448702
ko04014	Ras signaling pathway	68/1182	279/7206	0.000496938980327
ko04924	Renin secretion	27/1182	86/7206	0.000579119845312
ko04540	Gap junction	36/1182	128/7206	0.000679058229466
ko05162	Measles	7/1182	120/7206	0.000699702057872
ko04750	Inflammatory mediator regulation of TRP channels	35/1182	122/7206	0.000734615854594
ko05161	Hepatitis B	13/1182	173/7206	0.000797909812732
ko04010	MAPK signaling pathway	75/1182	321/7206	0.000892216419834
ko05166	HTLV-I infection	28/1182	292/7206	0.000892468869738
ko04514	Cell adhesion molecules (CAMs)	36/1182	130/7206	0.00109607391337
ko04964	Proximal tubule bicarbonate reclamation	12/1182	29/7206	0.00121298307973
ko04064	NF-kappa B signaling pathway	5/1182	96/7206	0.00127697263941
ko05205	Proteoglycans in cancer	26/1182	271/7206	0.00141959299675
ko05140	Leishmaniasis	3/1182	75/7206	0.00149156128803
ko04360	Axon guidance	57/1182	233/7206	0.00153819828645
ko04922	Glucagon signaling pathway	35/1182	128/7206	0.00156770542187
ko04630	Jak-STAT signaling pathway	9/1182	132/7206	0.00182170936233
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1182	79/7206	0.00187970295627
ko04270	Vascular smooth muscle contraction	40/1182	154/7206	0.00199323807959
ko04930	Type II diabetes mellitus	18/1182	54/7206	0.00239765623223
ko04217	Necroptosis	15/1182	178/7206	0.00276280033738
ko05219	Bladder cancer	1/1182	48/7206	0.00292736524872
ko05110	Vibrio cholerae infection	20/1182	63/7206	0.00295287960131
ko03420	Nucleotide excision repair	1/1182	46/7206	0.00441073239519
ko04626	Plant-pathogen interaction	8/1182	18/7206	0.00477235151407
ko04960	Aldosterone-regulated sodium reabsorption	14/1182	41/7206	0.00482726771024
ko04612	Antigen processing and presentation	4/1182	77/7206	0.00484647873186
ko04976	Bile secretion	23/1182	80/7206	0.00555966513254
ko04915	Estrogen signaling pathway	34/1182	131/7206	0.00571730558212
ko03022	Basal transcription factors	1/1182	44/7206	0.00670289521076
ko05144	Malaria	1/1182	45/7206	0.00704651048804
ko05145	Toxoplasmosis	10/1182	126/7206	0.00730199427757
ko00280	Valine, leucine and isoleucine degradation	2/1182	54/7206	0.00851469127354
ko04330	Notch signaling pathway	3/1182	62/7206	0.00920459043852
ko04622	RIG-I-like receptor signaling pathway	3/1182	62/7206	0.00920459043852
ko04214	Apoptosis - fly	4/1182	72/7206	0.00965954344796
ko04260	Cardiac muscle contraction	26/1182	98/7206	0.0125081340177
ko04657	IL-17 signaling pathway	6/1182	87/7206	0.0127805281617
ko05133	Pertussis	6/1182	87/7206	0.0127805281617
ko04923	Regulation of lipolysis in adipocytes	21/1182	77/7206	0.013172516159
ko00562	Inositol phosphate metabolism	24/1182	89/7206	0.0132846001909
ko00630	Glyoxylate and dicarboxylate metabolism	1/1182	38/7206	0.0148295111775
ko03410	Base excision repair	1/1182	38/7206	0.0148295111775
ko04350	TGF-beta signaling pathway	8/1182	103/7206	0.0152038976531
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1182	14/7206	0.0175933464232
ko04550	Signaling pathways regulating pluripotency of stem cells	16/1182	165/7206	0.0187319469965
ko04973	Carbohydrate digestion and absorption	13/1182	42/7206	0.0189393069361
ko05016	Huntington's disease	23/1182	215/7206	0.019405600351
ko05414	Dilated cardiomyopathy	28/1182	112/7206	0.0197052207582
ko05131	Shigellosis	6/1182	82/7206	0.0236296637809
ko05200	Pathways in cancer	63/1182	492/7206	0.027075067141
ko05321	Inflammatory bowel disease (IBD)	3/1182	56/7206	0.0274166588478
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1182	100/7206	0.0283277389522
ko05222	Small cell lung cancer	7/1182	89/7206	0.0295537570694
ko04015	Rap1 signaling pathway	59/1182	278/7206	0.0314697452649
ko04610	Complement and coagulation cascades	6/1182	79/7206	0.0318153630621
ko04210	Apoptosis	19/1182	180/7206	0.0319213935777
ko00860	Porphyrin and chlorophyll metabolism	1/1182	34/7206	0.0335916067967
ko04113	Meiosis - yeast	5/1182	70/7206	0.0341910977748
ko04658	Th1 and Th2 cell differentiation	8/1182	96/7206	0.0360019366793
ko05220	Chronic myeloid leukemia	7/1182	85/7206	0.0389365742522
ko04620	Toll-like receptor signaling pathway	9/1182	100/7206	0.0415914283822
ko01524	Platinum drug resistance	6/1182	76/7206	0.0426846083884
ko05130	Pathogenic Escherichia coli infection	6/1182	77/7206	0.0429557770392
ko05217	Basal cell carcinoma	5/1182	68/7206	0.0467392578663
ko04711	Circadian rhythm - fly	5/1182	13/7206	0.0480108336377
ko05340	Primary immunodeficiency	1/1182	30/7206	0.0491728084346
ko05230	Central carbon metabolism in cancer	20/1182	81/7206	0.0494122458234