ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	146/917	423/7206	3.34607882991e-33
ko04721	Synaptic vesicle cycle	54/917	80/7206	3.2197245072e-30
ko04724	Glutamatergic synapse	70/917	152/7206	1.61723451663e-24
ko05033	Nicotine addiction	40/917	56/7206	3.9352282106e-24
ko04727	GABAergic synapse	49/917	110/7206	9.64076098771e-17
ko05032	Morphine addiction	49/917	110/7206	9.64076098771e-17
ko04713	Circadian entrainment	54/917	136/7206	1.15700973474e-15
ko04728	Dopaminergic synapse	65/917	185/7206	1.72815869937e-15
ko04725	Cholinergic synapse	55/917	160/7206	7.7924980548e-13
ko04723	Retrograde endocannabinoid signaling	57/917	175/7206	3.80415916927e-12
ko04024	cAMP signaling pathway	75/917	279/7206	8.43649481648e-11
ko04742	Taste transduction	27/917	61/7206	9.99740742081e-10
ko04911	Insulin secretion	40/917	117/7206	1.3359350442e-09
ko04966	Collecting duct acid secretion	16/917	26/7206	6.39752355995e-09
ko04726	Serotonergic synapse	43/917	137/7206	6.41835580843e-09
ko04744	Phototransduction	19/917	36/7206	8.33468912484e-09
ko05031	Amphetamine addiction	32/917	91/7206	2.80156330095e-08
ko03040	Spliceosome	1/917	145/7206	9.10597228919e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/917	205/7206	3.16381766601e-07
ko04921	Oxytocin signaling pathway	53/917	209/7206	4.46147485332e-07
ko04970	Salivary secretion	30/917	95/7206	1.09802775681e-06
ko04060	Cytokine-cytokine receptor interaction	5/917	191/7206	1.34753539748e-06
ko05030	Cocaine addiction	25/917	73/7206	1.63193317049e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/917	74/7206	2.17196926541e-06
ko05164	Influenza A	4/917	167/7206	3.05801097063e-06
ko04740	Olfactory transduction	26/917	80/7206	3.12315159871e-06
ko04514	Cell adhesion molecules (CAMs)	36/917	130/7206	3.57606417246e-06
ko04720	Long-term potentiation	30/917	99/7206	4.15135105599e-06
ko05168	Herpes simplex infection	5/917	182/7206	4.19383651491e-06
ko05110	Vibrio cholerae infection	22/917	63/7206	4.75569269641e-06
ko04120	Ubiquitin mediated proteolysis	3/917	138/7206	1.48414182495e-05
ko03013	RNA transport	5/917	166/7206	1.70190819649e-05
ko05203	Viral carcinogenesis	14/917	277/7206	2.03080352905e-05
ko04924	Renin secretion	26/917	86/7206	2.13960126933e-05
ko04260	Cardiac muscle contraction	28/917	98/7206	2.24926725459e-05
ko04360	Axon guidance	52/917	233/7206	3.44336119284e-05
ko04010	MAPK signaling pathway	66/917	321/7206	5.0394910369e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/917	14/7206	9.87000039973e-05
ko04020	Calcium signaling pathway	56/917	265/7206	0.000100740757865
ko05162	Measles	3/917	120/7206	0.00014352366997
ko04730	Long-term depression	22/917	78/7206	0.000217489236997
ko04621	NOD-like receptor signaling pathway	6/917	157/7206	0.00022831109536
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/917	59/7206	0.000251859185197
ko05205	Proteoglycans in cancer	16/917	271/7206	0.000262829986783
ko04022	cGMP-PKG signaling pathway	46/917	216/7206	0.000369059418674
ko05120	Epithelial cell signaling in Helicobacter pylori infection	24/917	92/7206	0.000420770237857
ko04141	Protein processing in endoplasmic reticulum	9/917	184/7206	0.000471611114523
ko04610	Complement and coagulation cascades	1/917	79/7206	0.000492098116227
ko03008	Ribosome biogenesis in eukaryotes	1/917	79/7206	0.000492098116227
ko04540	Gap junction	30/917	128/7206	0.000700506282477
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/917	79/7206	0.000902702721896
ko04214	Apoptosis - fly	1/917	72/7206	0.00107885043553
ko04971	Gastric acid secretion	24/917	98/7206	0.00117144648033
ko05169	Epstein-Barr virus infection	12/917	206/7206	0.00138150975497
ko04925	Aldosterone synthesis and secretion	25/917	105/7206	0.00163411573035
ko04145	Phagosome	35/917	162/7206	0.00171104291411
ko04064	NF-kappa B signaling pathway	3/917	96/7206	0.00183876893421
ko04964	Proximal tubule bicarbonate reclamation	10/917	29/7206	0.00216711973719
ko04110	Cell cycle	7/917	145/7206	0.00228030830143
ko04014	Ras signaling pathway	53/917	279/7206	0.00236867373229
ko04146	Peroxisome	3/917	89/7206	0.00375489310488
ko05322	Systemic lupus erythematosus	8/917	151/7206	0.00414504730683
ko05140	Leishmaniasis	2/917	75/7206	0.00465562358668
ko04626	Plant-pathogen interaction	7/917	18/7206	0.00470661363246
ko04915	Estrogen signaling pathway	28/917	131/7206	0.00503043919846
ko05323	Rheumatoid arthritis	21/917	89/7206	0.00562690360439
ko00240	Pyrimidine metabolism	5/917	110/7206	0.00586408187348
ko04976	Bile secretion	19/917	80/7206	0.00607884275459
ko00480	Glutathione metabolism	1/917	55/7206	0.00777406464454
ko05321	Inflammatory bowel disease (IBD)	1/917	56/7206	0.00780139016332
ko05166	HTLV-I infection	23/917	292/7206	0.00920242716231
ko05034	Alcoholism	44/917	238/7206	0.00977839004165
ko00590	Arachidonic acid metabolism	1/917	52/7206	0.0114866450878
ko04640	Hematopoietic cell lineage	2/917	64/7206	0.0138934444371
ko04972	Pancreatic secretion	23/917	111/7206	0.0145771137505
ko00190	Oxidative phosphorylation	26/917	127/7206	0.0145966223448
ko01524	Platinum drug resistance	3/917	76/7206	0.0150531028387
ko04612	Antigen processing and presentation	3/917	77/7206	0.0150985713676
ko04962	Vasopressin-regulated water reabsorption	14/917	58/7206	0.0156167399929
ko04140	Autophagy - animal	11/917	164/7206	0.0172600316874
ko04668	TNF signaling pathway	7/917	120/7206	0.018501461971
ko00330	Arginine and proline metabolism	2/917	61/7206	0.0199175166257
ko05161	Hepatitis B	12/917	173/7206	0.0202207091861
ko00561	Glycerolipid metabolism	2/917	63/7206	0.0205111923627
ko05414	Dilated cardiomyopathy	23/917	112/7206	0.0208726020793
ko00310	Lysine degradation	3/917	73/7206	0.0211261934677
ko05146	Amoebiasis	5/917	99/7206	0.0212616659774
ko04657	IL-17 signaling pathway	4/917	87/7206	0.0218010493418
ko04371	Apelin signaling pathway	33/917	177/7206	0.0218413784768
ko01200	Carbon metabolism	8/917	128/7206	0.0226964479405
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/917	182/7206	0.0234342213512
ko00620	Pyruvate metabolism	1/917	46/7206	0.0250222994525
ko03420	Nucleotide excision repair	1/917	46/7206	0.0250222994525
ko05204	Chemical carcinogenesis	1/917	48/7206	0.0262881083918
ko05145	Toxoplasmosis	8/917	126/7206	0.029981528007
ko03018	RNA degradation	4/917	84/7206	0.0302128102057
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/917	15/7206	0.0331429375568
ko00983	Drug metabolism - other enzymes	1/917	42/7206	0.0367863906514
ko05418	Fluid shear stress and atherosclerosis	13/917	173/7206	0.0371391225789
ko03022	Basal transcription factors	1/917	44/7206	0.0376072891401
ko00071	Fatty acid degradation	1/917	45/7206	0.0389730075919
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/917	26/7206	0.0393012782139
ko00280	Valine, leucine and isoleucine degradation	2/917	54/7206	0.0406135442196
ko00564	Glycerophospholipid metabolism	6/917	99/7206	0.0471410102172