ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/898	423/7206	2.07614630331e-46
ko04724	Glutamatergic synapse	78/898	152/7206	6.2069557851e-32
ko05033	Nicotine addiction	45/898	56/7206	2.85020846047e-31
ko05032	Morphine addiction	59/898	110/7206	1.09906290674e-25
ko04728	Dopaminergic synapse	77/898	185/7206	5.16680467854e-24
ko04727	GABAergic synapse	57/898	110/7206	7.63731725821e-24
ko04713	Circadian entrainment	63/898	136/7206	7.89520129053e-23
ko04721	Synaptic vesicle cycle	45/898	80/7206	5.63816660966e-21
ko04725	Cholinergic synapse	64/898	160/7206	4.95585696579e-19
ko04723	Retrograde endocannabinoid signaling	67/898	175/7206	1.14727730334e-18
ko04024	cAMP signaling pathway	87/898	279/7206	3.09238866504e-17
ko04726	Serotonergic synapse	52/898	137/7206	1.48145716445e-14
ko04921	Oxytocin signaling pathway	67/898	209/7206	3.7977593129e-14
ko04744	Phototransduction	24/898	36/7206	4.22999520589e-14
ko04742	Taste transduction	31/898	61/7206	3.22500883643e-13
ko05031	Amphetamine addiction	39/898	91/7206	3.26516600034e-13
ko04911	Insulin secretion	45/898	117/7206	5.30316105144e-13
ko04720	Long-term potentiation	40/898	99/7206	1.64606519255e-12
ko04020	Calcium signaling pathway	74/898	265/7206	6.91307178515e-12
ko04261	Adrenergic signaling in cardiomyocytes	62/898	205/7206	7.24263097925e-12
ko05030	Cocaine addiction	29/898	73/7206	3.16379298688e-09
ko04060	Cytokine-cytokine receptor interaction	3/898	191/7206	4.48066277973e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/898	74/7206	9.21563182518e-08
ko03040	Spliceosome	1/898	145/7206	1.4388180653e-07
ko04970	Salivary secretion	31/898	95/7206	2.0014428144e-07
ko05164	Influenza A	3/898	167/7206	6.99643126315e-07
ko04010	MAPK signaling pathway	70/898	321/7206	1.53231103153e-06
ko05203	Viral carcinogenesis	11/898	277/7206	1.57534186726e-06
ko04925	Aldosterone synthesis and secretion	31/898	105/7206	3.08758718485e-06
ko04966	Collecting duct acid secretion	13/898	26/7206	3.49935373984e-06
ko04730	Long-term depression	25/898	78/7206	4.36856778507e-06
ko05168	Herpes simplex infection	5/898	182/7206	6.08798562906e-06
ko04971	Gastric acid secretion	29/898	98/7206	6.63208725493e-06
ko04022	cGMP-PKG signaling pathway	50/898	216/7206	8.73456832786e-06
ko04260	Cardiac muscle contraction	28/898	98/7206	1.61405400916e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/898	79/7206	1.88087501594e-05
ko04745	Phototransduction - fly	15/898	38/7206	2.30739653662e-05
ko04740	Olfactory transduction	24/898	80/7206	2.37570303597e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/898	14/7206	8.47439210263e-05
ko04924	Renin secretion	24/898	86/7206	9.6802086357e-05
ko05169	Epstein-Barr virus infection	9/898	206/7206	9.8797570862e-05
ko05322	Systemic lupus erythematosus	5/898	151/7206	0.000147931595744
ko04141	Protein processing in endoplasmic reticulum	8/898	184/7206	0.000253649683635
ko04514	Cell adhesion molecules (CAMs)	31/898	130/7206	0.000256242546974
ko04621	NOD-like receptor signaling pathway	6/898	157/7206	0.000326062904545
ko04072	Phospholipase D signaling pathway	42/898	197/7206	0.00040187589134
ko03013	RNA transport	7/898	166/7206	0.000478059483443
ko04540	Gap junction	30/898	128/7206	0.00058681323929
ko04120	Ubiquitin mediated proteolysis	5/898	138/7206	0.000593759327233
ko05110	Vibrio cholerae infection	18/898	63/7206	0.000694442340995
ko05414	Dilated cardiomyopathy	27/898	112/7206	0.000711083810742
ko04070	Phosphatidylinositol signaling system	27/898	112/7206	0.000711083810742
ko04915	Estrogen signaling pathway	30/898	131/7206	0.000731212394072
ko04612	Antigen processing and presentation	1/898	77/7206	0.000738975471835
ko05162	Measles	4/898	120/7206	0.000741621600902
ko04360	Axon guidance	47/898	233/7206	0.000785469124622
ko04972	Pancreatic secretion	26/898	111/7206	0.00120764627894
ko04350	TGF-beta signaling pathway	3/898	103/7206	0.00132607341558
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/898	59/7206	0.00215013791125
ko04750	Inflammatory mediator regulation of TRP channels	27/898	122/7206	0.0022258961061
ko04110	Cell cycle	7/898	145/7206	0.00316401705283
ko03008	Ribosome biogenesis in eukaryotes	2/898	79/7206	0.00323207091422
ko04640	Hematopoietic cell lineage	1/898	64/7206	0.00361280792557
ko04626	Plant-pathogen interaction	7/898	18/7206	0.00417777225151
ko05161	Hepatitis B	10/898	173/7206	0.00491496530448
ko04146	Peroxisome	3/898	89/7206	0.00542420238703
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/898	182/7206	0.00604289811778
ko05034	Alcoholism	44/898	238/7206	0.00673622378117
ko00310	Lysine degradation	2/898	73/7206	0.00678786061153
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/898	15/7206	0.00679755641898
ko04964	Proximal tubule bicarbonate reclamation	9/898	29/7206	0.00684410497714
ko04014	Ras signaling pathway	50/898	279/7206	0.00711225887411
ko05140	Leishmaniasis	2/898	75/7206	0.00715003393376
ko05321	Inflammatory bowel disease (IBD)	1/898	56/7206	0.00786844533428
ko00240	Pyrimidine metabolism	5/898	110/7206	0.00820982747306
ko05205	Proteoglycans in cancer	20/898	271/7206	0.00841474633624
ko05166	HTLV-I infection	22/898	292/7206	0.00842841713146
ko05410	Hypertrophic cardiomyopathy (HCM)	22/898	100/7206	0.00853009421579
ko03018	RNA degradation	3/898	84/7206	0.0113041198066
ko04064	NF-kappa B signaling pathway	4/898	96/7206	0.0116205164501
ko00480	Glutathione metabolism	1/898	55/7206	0.0119621509576
ko04670	Leukocyte transendothelial migration	9/898	151/7206	0.0122169675529
ko04371	Apelin signaling pathway	33/898	177/7206	0.0152693641472
ko04071	Sphingolipid signaling pathway	31/898	162/7206	0.0153130146621
ko04510	Focal adhesion	18/898	240/7206	0.0166700835102
ko05215	Prostate cancer	6/898	111/7206	0.0198776132676
ko04657	IL-17 signaling pathway	4/898	87/7206	0.0214349052606
ko04630	Jak-STAT signaling pathway	8/898	132/7206	0.0229665936955
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/898	92/7206	0.0246492904153
ko04668	TNF signaling pathway	7/898	120/7206	0.0248860744665
ko04976	Bile secretion	17/898	80/7206	0.0251548767355
ko04912	GnRH signaling pathway	24/898	122/7206	0.0255994095202
ko04210	Apoptosis	13/898	180/7206	0.0295107894476
ko00330	Arginine and proline metabolism	2/898	61/7206	0.0295563065049
ko04214	Apoptosis - fly	3/898	72/7206	0.0299293689361
ko05231	Choline metabolism in cancer	25/898	134/7206	0.0341921229215
ko04114	Oocyte meiosis	26/898	139/7206	0.0366208133588
ko03022	Basal transcription factors	1/898	44/7206	0.0371884444707
ko00071	Fatty acid degradation	1/898	45/7206	0.0379563514753
ko03420	Nucleotide excision repair	1/898	46/7206	0.0393354372364
ko05010	Alzheimer's disease	35/898	202/7206	0.0396102304884
ko05214	Glioma	16/898	79/7206	0.0402740565595
ko05217	Basal cell carcinoma	3/898	68/7206	0.0414758579474
ko03320	PPAR signaling pathway	3/898	69/7206	0.0418684873045
ko05418	Fluid shear stress and atherosclerosis	13/898	173/7206	0.0470937407694