ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	43/431	152/7206	1.26525801854e-18
ko05033	Nicotine addiction	25/431	56/7206	1.32622437917e-16
ko05032	Morphine addiction	34/431	110/7206	3.08288041163e-16
ko04080	Neuroactive ligand-receptor interaction	70/431	423/7206	1.1391788227e-15
ko04713	Circadian entrainment	36/431	136/7206	9.30030617554e-15
ko04728	Dopaminergic synapse	41/431	185/7206	8.93081091401e-14
ko04911	Insulin secretion	32/431	117/7206	1.12184358969e-13
ko04727	GABAergic synapse	31/431	110/7206	1.12746550306e-13
ko04744	Phototransduction	18/431	36/7206	2.26707685411e-13
ko04723	Retrograde endocannabinoid signaling	37/431	175/7206	7.00337231585e-12
ko04024	cAMP signaling pathway	47/431	279/7206	4.82323077925e-11
ko04725	Cholinergic synapse	33/431	160/7206	2.02690000337e-10
ko04721	Synaptic vesicle cycle	22/431	80/7206	7.73029663822e-10
ko04921	Oxytocin signaling pathway	35/431	209/7206	1.9354696424e-08
ko04726	Serotonergic synapse	27/431	137/7206	2.64692867094e-08
ko04720	Long-term potentiation	22/431	99/7206	5.63076817415e-08
ko05030	Cocaine addiction	18/431	73/7206	1.73824965066e-07
ko05031	Amphetamine addiction	20/431	91/7206	2.76595347447e-07
ko04970	Salivary secretion	20/431	95/7206	5.79323576222e-07
ko04261	Adrenergic signaling in cardiomyocytes	29/431	205/7206	1.38704530971e-05
ko04020	Calcium signaling pathway	34/431	265/7206	2.69549787095e-05
ko04925	Aldosterone synthesis and secretion	18/431	105/7206	4.26180878639e-05
ko04742	Taste transduction	13/431	61/7206	4.89804019624e-05
ko05203	Viral carcinogenesis	3/431	277/7206	7.55172583721e-05
ko04972	Pancreatic secretion	18/431	111/7206	9.07080383004e-05
ko04730	Long-term depression	14/431	78/7206	0.000181956619427
ko04971	Gastric acid secretion	16/431	98/7206	0.000204134833652
ko04022	cGMP-PKG signaling pathway	27/431	216/7206	0.00021722349514
ko04745	Phototransduction - fly	9/431	38/7206	0.00030964607263
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/431	59/7206	0.000633136684769
ko04540	Gap junction	18/431	128/7206	0.000909666317175
ko04070	Phosphatidylinositol signaling system	16/431	112/7206	0.000946998237505
ko05034	Alcoholism	27/431	238/7206	0.00118082649802
ko05014	Amyotrophic lateral sclerosis (ALS)	12/431	74/7206	0.001330822415
ko05322	Systemic lupus erythematosus	1/431	151/7206	0.00150741301677
ko05168	Herpes simplex infection	2/431	182/7206	0.00214806512941
ko04740	Olfactory transduction	12/431	80/7206	0.00264049313159
ko04626	Plant-pathogen interaction	5/431	18/7206	0.00334471601374
ko05164	Influenza A	2/431	167/7206	0.00429879096677
ko04630	Jak-STAT signaling pathway	1/431	132/7206	0.00471160469827
ko04924	Renin secretion	12/431	86/7206	0.00484741316341
ko04060	Cytokine-cytokine receptor interaction	3/431	191/7206	0.00489176160637
ko04072	Phospholipase D signaling pathway	22/431	197/7206	0.00527037695226
ko05166	HTLV-I infection	7/431	292/7206	0.00527678914163
ko04510	Focal adhesion	5/431	240/7206	0.00541115793417
ko04750	Inflammatory mediator regulation of TRP channels	15/431	122/7206	0.00641816711358
ko04964	Proximal tubule bicarbonate reclamation	6/431	29/7206	0.00646854216711
ko04810	Regulation of actin cytoskeleton	6/431	264/7206	0.00749349380163
ko04260	Cardiac muscle contraction	13/431	98/7206	0.00760357548641
ko00230	Purine metabolism	21/431	194/7206	0.00809101070283
ko04960	Aldosterone-regulated sodium reabsorption	7/431	41/7206	0.00997995368792
ko03040	Spliceosome	2/431	145/7206	0.0121750656799
ko04514	Cell adhesion molecules (CAMs)	15/431	130/7206	0.0133862203795
ko04371	Apelin signaling pathway	19/431	177/7206	0.0144303240243
ko04120	Ubiquitin mediated proteolysis	2/431	138/7206	0.0171966310406
ko04966	Collecting duct acid secretion	5/431	26/7206	0.0173129726577
ko04918	Thyroid hormone synthesis	11/431	86/7206	0.0178072023504
ko03013	RNA transport	3/431	166/7206	0.0187807473372
ko04062	Chemokine signaling pathway	20/431	201/7206	0.0226277725809
ko05169	Epstein-Barr virus infection	5/431	206/7206	0.0246306838867
ko04978	Mineral absorption	6/431	40/7206	0.0300940360889
ko05224	Breast cancer	4/431	174/7206	0.034434617685
ko05205	Proteoglycans in cancer	8/431	271/7206	0.0352210822968
ko04973	Carbohydrate digestion and absorption	6/431	42/7206	0.0372362631484
ko04940	Type I diabetes mellitus	5/431	32/7206	0.0395811491094
ko00562	Inositol phosphate metabolism	10/431	89/7206	0.042973362627
ko04668	TNF signaling pathway	2/431	120/7206	0.0487058147247
ko00680	Methane metabolism	5/431	34/7206	0.0496572868012