ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	177/922	423/7206	2.49008077499e-54
ko05033	Nicotine addiction	47/922	56/7206	9.10109937579e-34
ko04724	Glutamatergic synapse	79/922	152/7206	5.10870466585e-32
ko04713	Circadian entrainment	68/922	136/7206	2.35076284118e-26
ko05032	Morphine addiction	60/922	110/7206	5.30809038244e-26
ko04727	GABAergic synapse	58/922	110/7206	3.72922036342e-24
ko04721	Synaptic vesicle cycle	48/922	80/7206	1.71086603746e-23
ko04728	Dopaminergic synapse	75/922	185/7206	7.525974796e-22
ko04723	Retrograde endocannabinoid signaling	70/922	175/7206	4.62087571026e-20
ko04725	Cholinergic synapse	65/922	160/7206	4.04086787299e-19
ko04024	cAMP signaling pathway	88/922	279/7206	6.07271253369e-17
ko04911	Insulin secretion	50/922	117/7206	4.78415660986e-16
ko04020	Calcium signaling pathway	82/922	265/7206	2.24331265875e-15
ko04921	Oxytocin signaling pathway	67/922	209/7206	1.39314776714e-13
ko04726	Serotonergic synapse	51/922	137/7206	1.92174917179e-13
ko04742	Taste transduction	31/922	61/7206	6.63490904415e-13
ko04720	Long-term potentiation	40/922	99/7206	3.89009172308e-12
ko05031	Amphetamine addiction	38/922	91/7206	4.0383232748e-12
ko04261	Adrenergic signaling in cardiomyocytes	61/922	205/7206	7.57256670877e-11
ko04970	Salivary secretion	34/922	95/7206	7.05935348291e-09
ko04744	Phototransduction	19/922	36/7206	9.13474995399e-09
ko04971	Gastric acid secretion	33/922	98/7206	6.52604843663e-08
ko03040	Spliceosome	1/922	145/7206	9.32456036086e-08
ko05030	Cocaine addiction	27/922	73/7206	1.15473535714e-07
ko04925	Aldosterone synthesis and secretion	34/922	105/7206	1.22584702693e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/922	74/7206	6.38291529757e-07
ko05203	Viral carcinogenesis	12/922	277/7206	2.15563072559e-06
ko05168	Herpes simplex infection	5/922	182/7206	2.72629169738e-06
ko04010	MAPK signaling pathway	70/922	321/7206	4.63049097895e-06
ko04966	Collecting duct acid secretion	13/922	26/7206	4.72372786822e-06
ko04972	Pancreatic secretion	32/922	111/7206	5.23438781656e-06
ko04745	Phototransduction - fly	16/922	38/7206	6.44387234994e-06
ko04740	Olfactory transduction	25/922	80/7206	1.16222241671e-05
ko05164	Influenza A	5/922	167/7206	1.72006005493e-05
ko04022	cGMP-PKG signaling pathway	50/922	216/7206	1.84182817663e-05
ko05322	Systemic lupus erythematosus	4/922	151/7206	1.97796608789e-05
ko04621	NOD-like receptor signaling pathway	5/922	157/7206	5.01419234192e-05
ko05110	Vibrio cholerae infection	20/922	63/7206	6.71400977279e-05
ko04072	Phospholipase D signaling pathway	45/922	197/7206	7.97189629525e-05
ko04120	Ubiquitin mediated proteolysis	4/922	138/7206	8.55789786747e-05
ko04514	Cell adhesion molecules (CAMs)	33/922	130/7206	8.6407390816e-05
ko04260	Cardiac muscle contraction	27/922	98/7206	8.64975834025e-05
ko04730	Long-term depression	23/922	78/7206	9.35742003155e-05
ko04060	Cytokine-cytokine receptor interaction	8/922	191/7206	9.71033103251e-05
ko04540	Gap junction	32/922	128/7206	0.000141045912805
ko05169	Epstein-Barr virus infection	10/922	206/7206	0.000183914027114
ko04141	Protein processing in endoplasmic reticulum	8/922	184/7206	0.000184506295837
ko03013	RNA transport	7/922	166/7206	0.000238601488696
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/922	79/7206	0.000276111181079
ko04750	Inflammatory mediator regulation of TRP channels	30/922	122/7206	0.000307001987971
ko04070	Phosphatidylinositol signaling system	28/922	112/7206	0.000473890445072
ko04612	Antigen processing and presentation	1/922	77/7206	0.000480694229215
ko04110	Cell cycle	6/922	145/7206	0.000611282140222
ko05162	Measles	4/922	120/7206	0.000761164901292
ko04626	Plant-pathogen interaction	8/922	18/7206	0.000932295692408
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/922	59/7206	0.00112539908976
ko04915	Estrogen signaling pathway	30/922	131/7206	0.00130920047803
ko04964	Proximal tubule bicarbonate reclamation	10/922	29/7206	0.00225876201071
ko04360	Axon guidance	46/922	233/7206	0.00258740168896
ko05205	Proteoglycans in cancer	19/922	271/7206	0.00285008219468
ko04924	Renin secretion	21/922	86/7206	0.00291659279984
ko04610	Complement and coagulation cascades	2/922	79/7206	0.00329870169943
ko03008	Ribosome biogenesis in eukaryotes	2/922	79/7206	0.00329870169943
ko04976	Bile secretion	20/922	80/7206	0.00344813774331
ko04330	Notch signaling pathway	1/922	62/7206	0.00353410713339
ko05161	Hepatitis B	10/922	173/7206	0.003686735566
ko04146	Peroxisome	3/922	89/7206	0.00373462388321
ko05414	Dilated cardiomyopathy	25/922	112/7206	0.00415996858907
ko04350	TGF-beta signaling pathway	4/922	103/7206	0.00417873734614
ko04014	Ras signaling pathway	52/922	279/7206	0.00443656479889
ko04510	Focal adhesion	17/922	240/7206	0.00568540278368
ko04214	Apoptosis - fly	2/922	72/7206	0.00680048756722
ko00310	Lysine degradation	2/922	73/7206	0.00703205051204
ko00480	Glutathione metabolism	1/922	55/7206	0.00774322581121
ko04630	Jak-STAT signaling pathway	7/922	132/7206	0.00787049399631
ko04064	NF-kappa B signaling pathway	4/922	96/7206	0.00808912771351
ko04912	GnRH signaling pathway	26/922	122/7206	0.00861567249974
ko05166	HTLV-I infection	23/922	292/7206	0.00922674777946
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/922	182/7206	0.00933508416324
ko05215	Prostate cancer	6/922	111/7206	0.0145820146585
ko01524	Platinum drug resistance	3/922	76/7206	0.0150119355869
ko05222	Small cell lung cancer	4/922	89/7206	0.0154983077941
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/922	92/7206	0.0169835366245
ko05200	Pathways in cancer	46/922	492/7206	0.0172732512847
ko04550	Signaling pathways regulating pluripotency of stem cells	11/922	165/7206	0.017570846451
ko05231	Choline metabolism in cancer	27/922	134/7206	0.0177562932548
ko04670	Leukocyte transendothelial migration	10/922	151/7206	0.0189289947146
ko00240	Pyrimidine metabolism	6/922	110/7206	0.0201123622965
ko05140	Leishmaniasis	3/922	75/7206	0.0218756809624
ko04371	Apelin signaling pathway	33/922	177/7206	0.0224533357048
ko04210	Apoptosis	13/922	180/7206	0.0231430001142
ko05144	Malaria	1/922	45/7206	0.0249670279045
ko00071	Fatty acid degradation	1/922	45/7206	0.0249670279045
ko03420	Nucleotide excision repair	1/922	46/7206	0.0250256837453
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/922	14/7206	0.0251463693452
ko05219	Bladder cancer	1/922	48/7206	0.0265324129442
ko05034	Alcoholism	42/922	238/7206	0.0293221336714
ko04113	Meiosis - yeast	3/922	70/7206	0.0296017816483
ko04916	Melanogenesis	27/922	142/7206	0.030547909739
ko04140	Autophagy - animal	12/922	164/7206	0.0327720281255
ko04960	Aldosterone-regulated sodium reabsorption	10/922	41/7206	0.0341049604473
ko05410	Hypertrophic cardiomyopathy (HCM)	20/922	100/7206	0.0348808091903
ko04668	TNF signaling pathway	8/922	120/7206	0.0389623466248
ko04922	Glucagon signaling pathway	24/922	128/7206	0.0456116150864