ko pathway ratio_in_study ratio_in_pop p_value ko05205 Proteoglycans in cancer 28/201 271/7206 1.36631930193e-09 ko04668 TNF signaling pathway 18/201 120/7206 4.35603035671e-09 ko04512 ECM-receptor interaction 14/201 79/7206 2.76998477873e-08 ko04657 IL-17 signaling pathway 14/201 87/7206 9.89193909666e-08 ko04380 Osteoclast differentiation 17/201 134/7206 1.52196155417e-07 ko04933 AGE-RAGE signaling pathway in diabetic complications 17/201 135/7206 1.69893478388e-07 ko05200 Pathways in cancer 34/201 492/7206 5.93633793359e-07 ko04060 Cytokine-cytokine receptor interaction 19/201 191/7206 1.31043126795e-06 ko04510 Focal adhesion 21/201 240/7206 2.90009491747e-06 ko04974 Protein digestion and absorption 12/201 96/7206 1.27632270831e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/201 79/7206 6.13828500306e-05 ko04064 NF-kappa B signaling pathway 11/201 96/7206 6.70218648126e-05 ko05160 Hepatitis C 14/201 153/7206 8.65507862291e-05 ko04151 PI3K-Akt signaling pathway 25/201 390/7206 8.80017136967e-05 ko05146 Amoebiasis 11/201 99/7206 8.90506194804e-05 ko05206 MicroRNAs in cancer 15/201 177/7206 0.00011622486509 ko04670 Leukocyte transendothelial migration 13/201 151/7206 0.000285321662463 ko05418 Fluid shear stress and atherosclerosis 14/201 173/7206 0.000318349520307 ko05224 Breast cancer 14/201 174/7206 0.000337825034902 ko04912 GnRH signaling pathway 11/201 122/7206 0.000566891375313 ko04611 Platelet activation 13/201 163/7206 0.000598617410073 ko01522 Endocrine resistance 11/201 124/7206 0.000650815798522 ko05166 HTLV-I infection 19/201 292/7206 0.000698650599098 ko05222 Small cell lung cancer 9/201 89/7206 0.000788423741183 ko04621 NOD-like receptor signaling pathway 12/201 157/7206 0.00140401311259 ko05100 Bacterial invasion of epithelial cells 9/201 99/7206 0.00168995012303 ko04640 Hematopoietic cell lineage 7/201 64/7206 0.001911602896 ko05131 Shigellosis 8/201 82/7206 0.00193795425379 ko05219 Bladder cancer 6/201 48/7206 0.00201977731384 ko04015 Rap1 signaling pathway 17/201 278/7206 0.00221279158756 ko04390 Hippo signaling pathway 13/201 188/7206 0.00222273822044 ko04660 T cell receptor signaling pathway 10/201 124/7206 0.00234521538848 ko04012 ErbB signaling pathway 9/201 109/7206 0.00327788414647 ko04072 Phospholipase D signaling pathway 13/201 197/7206 0.0033443492744 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/201 92/7206 0.00399473212247 ko04210 Apoptosis 12/201 180/7206 0.00438360759827 ko04931 Insulin resistance 10/201 137/7206 0.00482290856544 ko04370 VEGF signaling pathway 7/201 77/7206 0.0054611412417 ko05132 Salmonella infection 8/201 98/7206 0.00586197113082 ko04916 Melanogenesis 10/201 142/7206 0.00619733476228 ko05410 Hypertrophic cardiomyopathy (HCM) 8/201 100/7206 0.00661270178872 ko04620 Toll-like receptor signaling pathway 8/201 100/7206 0.00661270178872 ko05164 Influenza A 11/201 167/7206 0.00686216849164 ko05161 Hepatitis B 11/201 173/7206 0.00886242322168 ko05142 Chagas disease (American trypanosomiasis) 9/201 130/7206 0.0102719114427 ko04514 Cell adhesion molecules (CAMs) 9/201 130/7206 0.0102719114427 ko04915 Estrogen signaling pathway 9/201 131/7206 0.0107712289116 ko04810 Regulation of actin cytoskeleton 15/201 264/7206 0.0111989102563 ko05217 Basal cell carcinoma 6/201 68/7206 0.0113846944348 ko04014 Ras signaling pathway 15/201 279/7206 0.0140271178701 ko00590 Arachidonic acid metabolism 5/201 52/7206 0.0144328288921 ko05134 Legionellosis 6/201 74/7206 0.0168068578602 ko05211 Renal cell carcinoma 7/201 96/7206 0.0174145295613 ko04658 Th1 and Th2 cell differentiation 7/201 96/7206 0.0174145295613 ko05140 Leishmaniasis 6/201 75/7206 0.0178576630892 ko04672 Intestinal immune network for IgA production 4/201 37/7206 0.0189029217496 ko04750 Inflammatory mediator regulation of TRP channels 8/201 122/7206 0.0204190920222 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/201 191/7206 0.0218139786514 ko04550 Signaling pathways regulating pluripotency of stem cells 10/201 165/7206 0.0257032612471 ko05212 Pancreatic cancer 6/201 83/7206 0.0279209496622 ko01521 EGFR tyrosine kinase inhibitor resistance 7/201 106/7206 0.0282744296564 ko05221 Acute myeloid leukemia 5/201 63/7206 0.0305854742574 ko05220 Chronic myeloid leukemia 6/201 85/7206 0.0309223778567 ko04218 Cellular senescence 10/201 177/7206 0.0322766145246 ko05210 Colorectal cancer 6/201 86/7206 0.0324992801976 ko05133 Pertussis 6/201 87/7206 0.0341276686521 ko05215 Prostate cancer 7/201 111/7206 0.0351298086051 ko04310 Wnt signaling pathway 10/201 181/7206 0.0353284818872 ko04662 B cell receptor signaling pathway 6/201 88/7206 0.0358080253478 ko04530 Tight junction 12/201 228/7206 0.0364817784063 ko05414 Dilated cardiomyopathy 7/201 112/7206 0.0366222396279 ko05323 Rheumatoid arthritis 6/201 89/7206 0.0375408012861 ko04071 Sphingolipid signaling pathway 9/201 162/7206 0.0467384143957 ko04214 Apoptosis - fly 5/201 72/7206 0.0499487818883