ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko00190	Oxidative phosphorylation	41/420	127/7206	1.38623421517e-20
ko04260	Cardiac muscle contraction	34/420	98/7206	2.34738439668e-18
ko05010	Alzheimer's disease	48/420	202/7206	9.95024361383e-18
ko05012	Parkinson's disease	41/420	155/7206	4.68396077834e-17
ko05016	Huntington's disease	43/420	215/7206	3.81717915987e-13
ko05410	Hypertrophic cardiomyopathy (HCM)	28/420	100/7206	1.14786154395e-12
ko01200	Carbon metabolism	30/420	128/7206	2.58731611784e-11
ko05414	Dilated cardiomyopathy	27/420	112/7206	1.32534049555e-10
ko00010	Glycolysis / Gluconeogenesis	21/420	74/7206	6.23701264494e-10
ko00020	Citrate cycle (TCA cycle)	14/420	35/7206	3.16683279813e-09
ko04932	Non-alcoholic fatty liver disease (NAFLD)	33/420	182/7206	3.42385441901e-09
ko04261	Adrenergic signaling in cardiomyocytes	35/420	205/7206	5.88676510236e-09
ko04974	Protein digestion and absorption	21/420	96/7206	9.72441762416e-08
ko00620	Pyruvate metabolism	13/420	46/7206	1.29360015328e-06
ko04512	ECM-receptor interaction	17/420	79/7206	2.09441874803e-06
ko04510	Focal adhesion	33/420	240/7206	3.36579281011e-06
ko01230	Biosynthesis of amino acids	17/420	85/7206	6.04881185831e-06
ko04723	Retrograde endocannabinoid signaling	26/420	175/7206	8.36098085413e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/420	79/7206	9.59245191356e-06
ko00710	Carbon fixation in photosynthetic organisms	8/420	27/7206	0.000103466798705
ko05034	Alcoholism	2/420	238/7206	0.000110325621833
ko04062	Chemokine signaling pathway	1/420	201/7206	0.000163194692167
ko05416	Viral myocarditis	11/420	55/7206	0.0002686716855
ko00220	Arginine biosynthesis	7/420	24/7206	0.000315979632781
ko04020	Calcium signaling pathway	30/420	265/7206	0.00041524373544
ko00680	Methane metabolism	8/420	34/7206	0.000590086862263
ko04022	cGMP-PKG signaling pathway	25/420	216/7206	0.00094431920661
ko04072	Phospholipase D signaling pathway	2/420	197/7206	0.00100925258285
ko04140	Autophagy - animal	1/420	164/7206	0.00105237053886
ko03013	RNA transport	1/420	166/7206	0.00108726478081
ko04964	Proximal tubule bicarbonate reclamation	7/420	29/7206	0.00110583323033
ko00250	Alanine, aspartate and glutamate metabolism	8/420	38/7206	0.00129461724262
ko04060	Cytokine-cytokine receptor interaction	2/420	191/7206	0.00145781481235
ko05167	Kaposi's sarcoma-associated herpesvirus infection	2/420	191/7206	0.00145781481235
ko05203	Viral carcinogenesis	5/420	277/7206	0.00152375123792
ko04144	Endocytosis	8/420	342/7206	0.00286042098559
ko04110	Cell cycle	1/420	145/7206	0.00335571176149
ko05161	Hepatitis B	2/420	173/7206	0.00441473661972
ko04120	Ubiquitin mediated proteolysis	1/420	138/7206	0.00487510620227
ko00630	Glyoxylate and dicarboxylate metabolism	7/420	38/7206	0.00568266837347
ko00260	Glycine, serine and threonine metabolism	8/420	48/7206	0.0059988443533
ko04071	Sphingolipid signaling pathway	2/420	162/7206	0.00604717348347
ko03010	Ribosome	1/420	129/7206	0.00690941498268
ko05142	Chagas disease (American trypanosomiasis)	1/420	130/7206	0.00697790970396
ko04978	Mineral absorption	7/420	40/7206	0.00759469378093
ko00030	Pentose phosphate pathway	6/420	32/7206	0.00939441495174
ko04210	Apoptosis	3/420	180/7206	0.00956483814083
ko04150	mTOR signaling pathway	3/420	184/7206	0.00972508368369
ko01522	Endocrine resistance	1/420	124/7206	0.0102501999355
ko00350	Tyrosine metabolism	6/420	33/7206	0.0109324465585
ko04922	Glucagon signaling pathway	15/420	128/7206	0.0111638653262
ko05322	Systemic lupus erythematosus	2/420	151/7206	0.0124595943332
ko04724	Glutamatergic synapse	2/420	152/7206	0.0126264996435
ko00500	Starch and sucrose metabolism	6/420	35/7206	0.0145274605207
ko04921	Oxytocin signaling pathway	21/420	209/7206	0.015123957781
ko05218	Melanoma	11/420	85/7206	0.0158468313113
ko03040	Spliceosome	2/420	145/7206	0.0178332522605
ko04626	Plant-pathogen interaction	4/420	18/7206	0.01812334761
ko05166	HTLV-I infection	8/420	292/7206	0.0206840332762
ko04659	Th17 cell differentiation	1/420	106/7206	0.0208949146392
ko00330	Arginine and proline metabolism	8/420	61/7206	0.024287980239
ko04610	Complement and coagulation cascades	10/420	79/7206	0.024317526734
ko04950	Maturity onset diabetes of the young	5/420	29/7206	0.0244546365338
ko05152	Tuberculosis	4/420	187/7206	0.0255838946207
ko01210	2-Oxocarboxylic acid metabolism	4/420	20/7206	0.026180017674
ko04151	PI3K-Akt signaling pathway	33/420	390/7206	0.0262353071415
ko04620	Toll-like receptor signaling pathway	1/420	100/7206	0.0302088134586
ko04310	Wnt signaling pathway	4/420	181/7206	0.0348934876614
ko00280	Valine, leucine and isoleucine degradation	7/420	54/7206	0.0360084028861
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/420	92/7206	0.0434962946681
ko04064	NF-kappa B signaling pathway	1/420	96/7206	0.0444786415003
ko00640	Propanoate metabolism	5/420	34/7206	0.0452507301614
ko04668	TNF signaling pathway	2/420	120/7206	0.0477138933146