ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 14/211 30/7206 2.13281234404e-14 ko04060 Cytokine-cytokine receptor interaction 28/211 191/7206 9.4348429052e-13 ko04650 Natural killer cell mediated cytotoxicity 19/211 97/7206 3.04689814727e-11 ko04612 Antigen processing and presentation 17/211 77/7206 4.67415197345e-11 ko05140 Leishmaniasis 16/211 75/7206 3.07696484686e-10 ko05152 Tuberculosis 23/211 187/7206 4.09233295223e-09 ko04659 Th17 cell differentiation 17/211 106/7206 8.77810542242e-09 ko05162 Measles 18/211 120/7206 9.45123976387e-09 ko05330 Allograft rejection 9/211 24/7206 1.19203504908e-08 ko05145 Toxoplasmosis 18/211 126/7206 2.08250470667e-08 ko05321 Inflammatory bowel disease (IBD) 12/211 56/7206 5.22040488525e-08 ko04380 Osteoclast differentiation 18/211 134/7206 5.55184999993e-08 ko05164 Influenza A 20/211 167/7206 7.0522755106e-08 ko05332 Graft-versus-host disease 7/211 18/7206 4.04289432756e-07 ko05144 Malaria 10/211 45/7206 4.87616343864e-07 ko04660 T cell receptor signaling pathway 16/211 124/7206 5.49275201118e-07 ko04145 Phagosome 18/211 162/7206 1.01359535136e-06 ko05320 Autoimmune thyroid disease 8/211 29/7206 1.19585902733e-06 ko04062 Chemokine signaling pathway 20/211 201/7206 1.46439247476e-06 ko04658 Th1 and Th2 cell differentiation 13/211 96/7206 3.80114155103e-06 ko05150 Staphylococcus aureus infection 8/211 36/7206 7.06481095816e-06 ko04672 Intestinal immune network for IgA production 8/211 37/7206 8.78914106161e-06 ko05168 Herpes simplex infection 17/211 182/7206 2.15035650722e-05 ko03050 Proteasome 9/211 54/7206 2.2583272133e-05 ko04630 Jak-STAT signaling pathway 14/211 132/7206 2.86354832853e-05 ko04940 Type I diabetes mellitus 7/211 32/7206 3.01427344883e-05 ko04620 Toll-like receptor signaling pathway 12/211 100/7206 3.15841682599e-05 ko05133 Pertussis 11/211 87/7206 4.1531155364e-05 ko04662 B cell receptor signaling pathway 11/211 88/7206 4.62626028716e-05 ko04666 Fc gamma R-mediated phagocytosis 13/211 122/7206 5.28651236593e-05 ko04640 Hematopoietic cell lineage 9/211 64/7206 9.07462677664e-05 ko05310 Asthma 5/211 17/7206 9.52870553195e-05 ko04621 NOD-like receptor signaling pathway 14/211 157/7206 0.000191354450528 ko04664 Fc epsilon RI signaling pathway 9/211 77/7206 0.00038252288249 ko04514 Cell adhesion molecules (CAMs) 12/211 130/7206 0.000400840920164 ko04064 NF-kappa B signaling pathway 10/211 96/7206 0.000468908619886 ko04217 Necroptosis 14/211 178/7206 0.000693806400473 ko05416 Viral myocarditis 7/211 55/7206 0.00102695038371 ko05323 Rheumatoid arthritis 9/211 89/7206 0.00111338775911 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/211 191/7206 0.00138121364652 ko05142 Chagas disease (American trypanosomiasis) 11/211 130/7206 0.00143550817552 ko05146 Amoebiasis 9/211 99/7206 0.0023575166536 ko04670 Leukocyte transendothelial migration 11/211 151/7206 0.00464870806161 ko04610 Complement and coagulation cascades 7/211 79/7206 0.00813156252917 ko04611 Platelet activation 11/211 163/7206 0.00817957291663 ko05143 African trypanosomiasis 4/211 32/7206 0.0135136715198 ko05161 Hepatitis B 11/211 173/7206 0.0179705155244 ko05132 Salmonella infection 7/211 98/7206 0.024438231471 ko04020 Calcium signaling pathway 2/211 265/7206 0.0250243497559 ko04144 Endocytosis 17/211 342/7206 0.0307978703661 ko05010 Alzheimer's disease 1/211 202/7206 0.0317739037228 ko04622 RIG-I-like receptor signaling pathway 5/211 62/7206 0.0344789378908