ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 15/163 79/7206 1.67730586321e-10 ko04668 TNF signaling pathway 16/163 120/7206 9.13119084182e-09 ko04510 Focal adhesion 21/163 240/7206 8.47731658042e-08 ko05164 Influenza A 16/163 167/7206 9.77132736576e-07 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 11/163 79/7206 1.35474117219e-06 ko05161 Hepatitis B 16/163 173/7206 1.56942478561e-06 ko04060 Cytokine-cytokine receptor interaction 16/163 191/7206 5.76163463988e-06 ko04658 Th1 and Th2 cell differentiation 11/163 96/7206 9.48794946259e-06 ko04621 NOD-like receptor signaling pathway 14/163 157/7206 1.11330412282e-05 ko05145 Toxoplasmosis 12/163 126/7206 2.50387906504e-05 ko04380 Osteoclast differentiation 12/163 134/7206 4.6342685545e-05 ko04657 IL-17 signaling pathway 9/163 87/7206 0.000140808585797 ko04662 B cell receptor signaling pathway 9/163 88/7206 0.000153853356916 ko04623 Cytosolic DNA-sensing pathway 6/163 41/7206 0.000285077521579 ko04974 Protein digestion and absorption 9/163 96/7206 0.000299234436189 ko05162 Measles 10/163 120/7206 0.000363608334029 ko05146 Amoebiasis 9/163 99/7206 0.000377078444477 ko05205 Proteoglycans in cancer 16/163 271/7206 0.000393387663093 ko05410 Hypertrophic cardiomyopathy (HCM) 9/163 100/7206 0.000406468490626 ko04620 Toll-like receptor signaling pathway 9/163 100/7206 0.000406468490626 ko04660 T cell receptor signaling pathway 10/163 124/7206 0.000473093475907 ko05131 Shigellosis 8/163 82/7206 0.00049654122556 ko04659 Th17 cell differentiation 9/163 106/7206 0.000625165248808 ko05142 Chagas disease (American trypanosomiasis) 10/163 130/7206 0.000687700874625 ko04210 Apoptosis 12/163 180/7206 0.00074426219451 ko05222 Small cell lung cancer 8/163 89/7206 0.000860838505915 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/163 191/7206 0.00125131832763 ko04064 NF-kappa B signaling pathway 8/163 96/7206 0.00141434331358 ko05160 Hepatitis C 10/163 153/7206 0.00237473219583 ko04622 RIG-I-like receptor signaling pathway 6/163 62/7206 0.002637404208 ko05168 Herpes simplex infection 11/163 182/7206 0.00269918272109 ko04933 AGE-RAGE signaling pathway in diabetic complications 9/163 135/7206 0.00341042522622 ko05133 Pertussis 7/163 87/7206 0.00341453664569 ko05414 Dilated cardiomyopathy 8/163 112/7206 0.00374128672352 ko04931 Insulin resistance 9/163 137/7206 0.00376209396443 ko04920 Adipocytokine signaling pathway 7/163 89/7206 0.00387790698317 ko04151 PI3K-Akt signaling pathway 18/163 390/7206 0.00407480335863 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/163 92/7206 0.00466067945144 ko04624 Toll and Imd signaling pathway 5/163 49/7206 0.00475649839139 ko04144 Endocytosis 16/163 342/7206 0.00478049879972 ko04650 Natural killer cell mediated cytotoxicity 7/163 97/7206 0.00622307806686 ko04912 GnRH signaling pathway 8/163 122/7206 0.00626797976388 ko05206 MicroRNAs in cancer 10/163 177/7206 0.00669566138154 ko01522 Endocrine resistance 8/163 124/7206 0.00690013626721 ko04932 Non-alcoholic fatty liver disease (NAFLD) 10/163 182/7206 0.00809490568042 ko05321 Inflammatory bowel disease (IBD) 5/163 56/7206 0.00839755471567 ko04810 Regulation of actin cytoskeleton 13/163 264/7206 0.00880077138327 ko04012 ErbB signaling pathway 7/163 109/7206 0.0115349260496 ko04218 Cellular senescence 9/163 177/7206 0.0187247189362 ko05166 HTLV-I infection 13/163 292/7206 0.0235704628118 ko05100 Bacterial invasion of epithelial cells 6/163 99/7206 0.0243489550418 ko05140 Leishmaniasis 5/163 75/7206 0.0269988677442 ko04630 Jak-STAT signaling pathway 7/163 132/7206 0.0297621135142 ko05152 Tuberculosis 9/163 187/7206 0.038789697049 ko05212 Pancreatic cancer 5/163 83/7206 0.0394013996474 ko05215 Prostate cancer 6/163 111/7206 0.0395571045531 ko05220 Chronic myeloid leukemia 5/163 85/7206 0.0429646758269 ko00254 Aflatoxin biosynthesis 1/163 2/7206 0.0447314800322 ko05210 Colorectal cancer 5/163 86/7206 0.0448169025408 ko05034 Alcoholism 1/163 238/7206 0.0452116517532