ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	175/1012	423/7206	1.42299441655e-46
ko05033	Nicotine addiction	45/1012	56/7206	5.77139458639e-29
ko04724	Glutamatergic synapse	73/1012	152/7206	3.09954188354e-24
ko05032	Morphine addiction	57/1012	110/7206	3.3113238999e-21
ko04721	Synaptic vesicle cycle	46/1012	80/7206	8.84054802949e-20
ko04728	Dopaminergic synapse	73/1012	185/7206	4.26553691153e-18
ko04727	GABAergic synapse	53/1012	110/7206	5.74805011763e-18
ko04713	Circadian entrainment	59/1012	136/7206	3.96659718424e-17
ko04024	cAMP signaling pathway	91/1012	279/7206	7.87211708935e-16
ko04723	Retrograde endocannabinoid signaling	65/1012	175/7206	1.02307559375e-14
ko04725	Cholinergic synapse	61/1012	160/7206	1.73826867864e-14
ko04020	Calcium signaling pathway	84/1012	265/7206	7.86439487211e-14
ko04921	Oxytocin signaling pathway	67/1012	209/7206	1.91210619962e-11
ko04742	Taste transduction	30/1012	61/7206	5.22194010122e-11
ko04726	Serotonergic synapse	48/1012	137/7206	3.6342073934e-10
ko04911	Insulin secretion	43/1012	117/7206	5.45705586998e-10
ko05031	Amphetamine addiction	36/1012	91/7206	1.36967191138e-09
ko04261	Adrenergic signaling in cardiomyocytes	61/1012	205/7206	4.19908277121e-09
ko03040	Spliceosome	1/1012	145/7206	9.07484462047e-09
ko04744	Phototransduction	19/1012	36/7206	4.33198424555e-08
ko04720	Long-term potentiation	35/1012	99/7206	6.97548438794e-08
ko03010	Ribosome	1/1012	129/7206	1.15552859988e-07
ko05203	Viral carcinogenesis	13/1012	277/7206	5.43659397115e-07
ko05322	Systemic lupus erythematosus	3/1012	151/7206	6.08924335209e-07
ko04970	Salivary secretion	32/1012	95/7206	1.4023104594e-06
ko04966	Collecting duct acid secretion	14/1012	26/7206	1.97483222354e-06
ko05030	Cocaine addiction	26/1012	73/7206	2.87539252625e-06
ko04070	Phosphatidylinositol signaling system	34/1012	112/7206	6.59497216759e-06
ko05168	Herpes simplex infection	7/1012	182/7206	7.04046254182e-06
ko04925	Aldosterone synthesis and secretion	32/1012	105/7206	1.20567916031e-05
ko03013	RNA transport	6/1012	166/7206	1.25440210128e-05
ko05164	Influenza A	6/1012	167/7206	1.29023815202e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1012	74/7206	1.30212542825e-05
ko04022	cGMP-PKG signaling pathway	54/1012	216/7206	1.4579688457e-05
ko04745	Phototransduction - fly	16/1012	38/7206	2.15984859797e-05
ko04514	Cell adhesion molecules (CAMs)	36/1012	130/7206	3.48291509584e-05
ko04060	Cytokine-cytokine receptor interaction	9/1012	191/7206	4.74078587246e-05
ko05169	Epstein-Barr virus infection	11/1012	206/7206	9.14986126114e-05
ko04120	Ubiquitin mediated proteolysis	5/1012	138/7206	9.43208699654e-05
ko04010	MAPK signaling pathway	70/1012	321/7206	0.000103413541789
ko03008	Ribosome biogenesis in eukaryotes	1/1012	79/7206	0.00013025583856
ko05162	Measles	4/1012	120/7206	0.000160663934847
ko04621	NOD-like receptor signaling pathway	7/1012	157/7206	0.000161855161661
ko04971	Gastric acid secretion	28/1012	98/7206	0.000174184943308
ko04740	Olfactory transduction	24/1012	80/7206	0.000239149408877
ko05166	HTLV-I infection	21/1012	292/7206	0.000282279188251
ko04626	Plant-pathogen interaction	9/1012	18/7206	0.000302113128558
ko05110	Vibrio cholerae infection	20/1012	63/7206	0.000316811680059
ko04730	Long-term depression	23/1012	78/7206	0.000395946886317
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1012	79/7206	0.000451053448746
ko04064	NF-kappa B signaling pathway	3/1012	96/7206	0.000570746080014
ko04110	Cell cycle	7/1012	145/7206	0.000609663242457
ko04072	Phospholipase D signaling pathway	45/1012	197/7206	0.000783414285467
ko05161	Hepatitis B	10/1012	173/7206	0.000794392024041
ko04360	Axon guidance	51/1012	233/7206	0.00102441295153
ko04260	Cardiac muscle contraction	26/1012	98/7206	0.00104019081992
ko04964	Proximal tubule bicarbonate reclamation	11/1012	29/7206	0.00121433310486
ko04972	Pancreatic secretion	28/1012	111/7206	0.00140978610722
ko04612	Antigen processing and presentation	2/1012	77/7206	0.00141196633069
ko04710	Circadian rhythm	14/1012	43/7206	0.00156826048521
ko05205	Proteoglycans in cancer	21/1012	271/7206	0.00170877169379
ko05140	Leishmaniasis	2/1012	75/7206	0.00212486086545
ko04014	Ras signaling pathway	57/1012	279/7206	0.00271281748892
ko04924	Renin secretion	22/1012	86/7206	0.00430113416117
ko04510	Focal adhesion	19/1012	240/7206	0.00438766322785
ko04141	Protein processing in endoplasmic reticulum	13/1012	184/7206	0.00487198493215
ko04610	Complement and coagulation cascades	3/1012	79/7206	0.00504700910219
ko04630	Jak-STAT signaling pathway	8/1012	132/7206	0.00515815528803
ko00520	Amino sugar and nucleotide sugar metabolism	1/1012	55/7206	0.00516264470379
ko05215	Prostate cancer	6/1012	111/7206	0.00552302169125
ko00590	Arachidonic acid metabolism	1/1012	52/7206	0.00764779452697
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1012	14/7206	0.00828819665917
ko05414	Dilated cardiomyopathy	26/1012	112/7206	0.008518622507
ko04330	Notch signaling pathway	2/1012	62/7206	0.00919696213436
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1012	92/7206	0.0096841005105
ko04214	Apoptosis - fly	3/1012	72/7206	0.0101477631029
ko04915	Estrogen signaling pathway	29/1012	131/7206	0.0106606378333
ko05219	Bladder cancer	1/1012	48/7206	0.0109830321669
ko04210	Apoptosis	14/1012	180/7206	0.0121535551312
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1012	100/7206	0.0133521738187
ko00562	Inositol phosphate metabolism	21/1012	89/7206	0.0134266282985
ko04350	TGF-beta signaling pathway	6/1012	103/7206	0.0141958896797
ko04922	Glucagon signaling pathway	28/1012	128/7206	0.0142236479236
ko03022	Basal transcription factors	1/1012	44/7206	0.0162083913506
ko03420	Nucleotide excision repair	1/1012	46/7206	0.0167275000028
ko04750	Inflammatory mediator regulation of TRP channels	27/1012	122/7206	0.0170012500932
ko04930	Type II diabetes mellitus	14/1012	54/7206	0.0174454406793
ko00480	Glutathione metabolism	2/1012	55/7206	0.0190721550279
ko05321	Inflammatory bowel disease (IBD)	2/1012	56/7206	0.0191380520144
ko05222	Small cell lung cancer	5/1012	89/7206	0.0200637573933
ko05200	Pathways in cancer	52/1012	492/7206	0.0220733952303
ko04611	Platelet activation	13/1012	163/7206	0.0221900993806
ko04658	Th1 and Th2 cell differentiation	6/1012	96/7206	0.0255335501418
ko05145	Toxoplasmosis	9/1012	126/7206	0.0267252655405
ko05016	Huntington's disease	19/1012	215/7206	0.0277071389901
ko00280	Valine, leucine and isoleucine degradation	2/1012	54/7206	0.0280577651156
ko04115	p53 signaling pathway	4/1012	74/7206	0.0280933949487
ko04540	Gap junction	27/1012	128/7206	0.0281020205966
ko01524	Platinum drug resistance	4/1012	76/7206	0.0289648833456
ko04668	TNF signaling pathway	9/1012	120/7206	0.0340875512457
ko04976	Bile secretion	18/1012	80/7206	0.0349506252308
ko03410	Base excision repair	1/1012	38/7206	0.0354687505669
ko00240	Pyrimidine metabolism	8/1012	110/7206	0.0376879867945
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/1012	59/7206	0.0382850016642
ko04622	RIG-I-like receptor signaling pathway	3/1012	62/7206	0.0408066371412
ko00680	Methane metabolism	9/1012	34/7206	0.0463507376411
ko04371	Apelin signaling pathway	34/1012	177/7206	0.0487998194658
ko04217	Necroptosis	16/1012	178/7206	0.0491534038162