ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	34/543	56/7206	1.10946686203e-24
ko04724	Glutamatergic synapse	45/543	152/7206	2.36973840213e-16
ko04721	Synaptic vesicle cycle	32/543	80/7206	3.46023237527e-16
ko04727	GABAergic synapse	35/543	110/7206	5.12427776341e-14
ko04728	Dopaminergic synapse	43/543	185/7206	1.10946910136e-11
ko04744	Phototransduction	18/543	36/7206	1.1780105047e-11
ko05032	Morphine addiction	31/543	110/7206	5.13542681805e-11
ko04723	Retrograde endocannabinoid signaling	40/543	175/7206	1.04194292642e-10
ko04024	cAMP signaling pathway	51/543	279/7206	1.70740521934e-09
ko04080	Neuroactive ligand-receptor interaction	67/543	423/7206	2.96860380642e-09
ko04713	Circadian entrainment	30/543	136/7206	5.72241622157e-08
ko04514	Cell adhesion molecules (CAMs)	29/543	130/7206	7.36338468326e-08
ko05203	Viral carcinogenesis	2/543	277/7206	1.49530452873e-07
ko04725	Cholinergic synapse	32/543	160/7206	2.33259476856e-07
ko04360	Axon guidance	40/543	233/7206	7.25334262972e-07
ko05030	Cocaine addiction	19/543	73/7206	1.14608232573e-06
ko04911	Insulin secretion	25/543	117/7206	1.39076923124e-06
ko04261	Adrenergic signaling in cardiomyocytes	34/543	205/7206	1.01596545289e-05
ko04010	MAPK signaling pathway	45/543	321/7206	4.82251582751e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/543	79/7206	6.19701846701e-05
ko04060	Cytokine-cytokine receptor interaction	2/543	191/7206	7.06145706276e-05
ko05031	Amphetamine addiction	18/543	91/7206	0.00012145288617
ko05169	Epstein-Barr virus infection	3/543	206/7206	0.00013872484869
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/543	14/7206	0.000316694228088
ko03040	Spliceosome	1/543	145/7206	0.00032353582406
ko05014	Amyotrophic lateral sclerosis (ALS)	15/543	74/7206	0.000333765514157
ko04120	Ubiquitin mediated proteolysis	1/543	138/7206	0.000455545316929
ko03013	RNA transport	2/543	166/7206	0.000469929064919
ko05164	Influenza A	2/543	167/7206	0.000482300572343
ko04141	Protein processing in endoplasmic reticulum	3/543	184/7206	0.000579474338146
ko04391	Hippo signaling pathway - fly	16/543	90/7206	0.000987965859132
ko04260	Cardiac muscle contraction	17/543	98/7206	0.00136420053498
ko04726	Serotonergic synapse	21/543	137/7206	0.00155406650279
ko04611	Platelet activation	3/543	163/7206	0.00235576211877
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/543	182/7206	0.00260764365404
ko00240	Pyrimidine metabolism	1/543	110/7206	0.00304464118975
ko04720	Long-term potentiation	16/543	99/7206	0.00317245015065
ko04621	NOD-like receptor signaling pathway	3/543	157/7206	0.00331285392289
ko05205	Proteoglycans in cancer	9/543	271/7206	0.00466927486051
ko04921	Oxytocin signaling pathway	27/543	209/7206	0.00495074131084
ko01200	Carbon metabolism	2/543	128/7206	0.00590088799076
ko05146	Amoebiasis	1/543	99/7206	0.00648930042011
ko05162	Measles	2/543	120/7206	0.00817055786293
ko04140	Autophagy - animal	4/543	164/7206	0.00991373322904
ko05414	Dilated cardiomyopathy	16/543	112/7206	0.0108785625306
ko05410	Hypertrophic cardiomyopathy (HCM)	15/543	100/7206	0.0110023923983
ko04218	Cellular senescence	5/543	177/7206	0.0132844219446
ko04217	Necroptosis	5/543	178/7206	0.013429517423
ko04512	ECM-receptor interaction	12/543	79/7206	0.0164797829547
ko04630	Jak-STAT signaling pathway	3/543	132/7206	0.0181474827848
ko05322	Systemic lupus erythematosus	4/543	151/7206	0.018209589479
ko05418	Fluid shear stress and atherosclerosis	5/543	173/7206	0.0182924653749
ko04137	Mitophagy - animal	1/543	82/7206	0.0199833327369
ko03018	RNA degradation	1/543	84/7206	0.0201757178913
ko05168	Herpes simplex infection	6/543	182/7206	0.022724299391
ko04350	TGF-beta signaling pathway	2/543	103/7206	0.0232491047163
ko04066	HIF-1 signaling pathway	3/543	123/7206	0.0245225278232
ko04110	Cell cycle	4/543	145/7206	0.0247516665252
ko04612	Antigen processing and presentation	1/543	77/7206	0.0289792191209
ko05161	Hepatitis B	6/543	173/7206	0.0400236351482
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/543	59/7206	0.0408334070051
ko04966	Collecting duct acid secretion	5/543	26/7206	0.0418545276183
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/543	26/7206	0.0418545276183
ko04214	Apoptosis - fly	1/543	72/7206	0.0419773043249
ko01524	Platinum drug resistance	1/543	76/7206	0.0443958784802
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/543	135/7206	0.0459306027415
ko04742	Taste transduction	9/543	61/7206	0.0459514885723
ko05215	Prostate cancer	3/543	111/7206	0.04654824967
ko04064	NF-kappa B signaling pathway	2/543	96/7206	0.047817884918
ko04022	cGMP-PKG signaling pathway	24/543	216/7206	0.0491674506007