ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	196/1214	423/7206	1.28645223197e-48
ko04724	Glutamatergic synapse	89/1214	152/7206	7.86312158827e-32
ko05033	Nicotine addiction	49/1214	56/7206	3.81266761707e-31
ko05032	Morphine addiction	67/1214	110/7206	1.37268804644e-25
ko04727	GABAergic synapse	66/1214	110/7206	1.08909151849e-24
ko04713	Circadian entrainment	74/1214	136/7206	7.05828921568e-24
ko04728	Dopaminergic synapse	86/1214	185/7206	1.80929265653e-21
ko04721	Synaptic vesicle cycle	50/1214	80/7206	4.34905694172e-20
ko04725	Cholinergic synapse	75/1214	160/7206	4.08601341161e-19
ko04723	Retrograde endocannabinoid signaling	77/1214	175/7206	1.36078302568e-17
ko04744	Phototransduction	28/1214	36/7206	1.27795581246e-15
ko04024	cAMP signaling pathway	101/1214	279/7206	2.33492476714e-15
ko04020	Calcium signaling pathway	97/1214	265/7206	3.42384401003e-15
ko04742	Taste transduction	37/1214	61/7206	1.37914074851e-14
ko04911	Insulin secretion	53/1214	117/7206	4.16970039991e-13
ko04726	Serotonergic synapse	58/1214	137/7206	1.13781584128e-12
ko04921	Oxytocin signaling pathway	77/1214	209/7206	1.55820033812e-12
ko05031	Amphetamine addiction	42/1214	91/7206	5.58481134703e-11
ko04261	Adrenergic signaling in cardiomyocytes	72/1214	205/7206	1.30336281711e-10
ko04720	Long-term potentiation	43/1214	99/7206	3.70846103291e-10
ko04360	Axon guidance	77/1214	233/7206	1.08604839223e-09
ko03040	Spliceosome	2/1214	145/7206	1.55573860843e-09
ko05203	Viral carcinogenesis	14/1214	277/7206	2.12916492261e-09
ko04740	Olfactory transduction	36/1214	80/7206	3.15196900862e-09
ko04970	Salivary secretion	38/1214	95/7206	8.10360770838e-08
ko04060	Cytokine-cytokine receptor interaction	8/1214	191/7206	1.15074842511e-07
ko05322	Systemic lupus erythematosus	5/1214	151/7206	2.50904693253e-07
ko04621	NOD-like receptor signaling pathway	6/1214	157/7206	7.14274401537e-07
ko05030	Cocaine addiction	30/1214	73/7206	7.40413145757e-07
ko03013	RNA transport	7/1214	166/7206	8.57627157345e-07
ko04925	Aldosterone synthesis and secretion	38/1214	105/7206	2.06042079791e-06
ko05164	Influenza A	8/1214	167/7206	2.89414010432e-06
ko04141	Protein processing in endoplasmic reticulum	10/1214	184/7206	3.45814031458e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1214	74/7206	4.67282632475e-06
ko04022	cGMP-PKG signaling pathway	63/1214	216/7206	4.71863385541e-06
ko05168	Herpes simplex infection	10/1214	182/7206	4.85256247132e-06
ko04610	Complement and coagulation cascades	1/1214	79/7206	1.26026988448e-05
ko04971	Gastric acid secretion	34/1214	98/7206	1.54454066798e-05
ko04514	Cell adhesion molecules (CAMs)	41/1214	130/7206	4.20754290316e-05
ko04010	MAPK signaling pathway	82/1214	321/7206	4.87587628882e-05
ko04745	Phototransduction - fly	17/1214	38/7206	5.22210520767e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1214	79/7206	5.44229102408e-05
ko04070	Phosphatidylinositol signaling system	36/1214	112/7206	5.96122113508e-05
ko04966	Collecting duct acid secretion	13/1214	26/7206	9.83975122289e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1214	79/7206	0.000110056467541
ko04612	Antigen processing and presentation	2/1214	77/7206	0.000166311100226
ko05205	Proteoglycans in cancer	24/1214	271/7206	0.000178757036966
ko04110	Cell cycle	9/1214	145/7206	0.000187033312487
ko05169	Epstein-Barr virus infection	16/1214	206/7206	0.000201863711229
ko05140	Leishmaniasis	2/1214	75/7206	0.000252989705748
ko04064	NF-kappa B signaling pathway	4/1214	96/7206	0.000274512594436
ko04972	Pancreatic secretion	34/1214	111/7206	0.000284925735459
ko04072	Phospholipase D signaling pathway	53/1214	197/7206	0.000317799345823
ko05414	Dilated cardiomyopathy	34/1214	112/7206	0.000322067301484
ko04730	Long-term depression	26/1214	78/7206	0.00034714891619
ko04924	Renin secretion	28/1214	86/7206	0.000375348677101
ko05162	Measles	7/1214	120/7206	0.000489580080783
ko04260	Cardiac muscle contraction	30/1214	98/7206	0.000609788616033
ko00480	Glutathione metabolism	1/1214	55/7206	0.000837984311678
ko04146	Peroxisome	4/1214	89/7206	0.000841085984674
ko04014	Ras signaling pathway	68/1214	279/7206	0.0010499197094
ko05110	Vibrio cholerae infection	21/1214	63/7206	0.00114819711092
ko04540	Gap junction	36/1214	128/7206	0.00118606075017
ko04120	Ubiquitin mediated proteolysis	10/1214	138/7206	0.00122119472784
ko05161	Hepatitis B	14/1214	173/7206	0.0013061444616
ko04976	Bile secretion	25/1214	80/7206	0.00135338898888
ko00240	Pyrimidine metabolism	7/1214	110/7206	0.00183448348147
ko04750	Inflammatory mediator regulation of TRP channels	34/1214	122/7206	0.00207657209075
ko04371	Apelin signaling pathway	45/1214	177/7206	0.0030933332723
ko04657	IL-17 signaling pathway	5/1214	87/7206	0.00351374509524
ko05321	Inflammatory bowel disease (IBD)	2/1214	56/7206	0.00378460005065
ko03022	Basal transcription factors	1/1214	44/7206	0.00432242903848
ko05144	Malaria	1/1214	45/7206	0.0043270706018
ko00071	Fatty acid degradation	1/1214	45/7206	0.0043270706018
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1214	14/7206	0.00433466176297
ko04915	Estrogen signaling pathway	35/1214	131/7206	0.00433632006703
ko03420	Nucleotide excision repair	1/1214	46/7206	0.00450926895424
ko03018	RNA degradation	5/1214	84/7206	0.00487710232852
ko04923	Regulation of lipolysis in adipocytes	23/1214	77/7206	0.00511326063004
ko04640	Hematopoietic cell lineage	3/1214	64/7206	0.00641451151103
ko04214	Apoptosis - fly	4/1214	72/7206	0.00667815474691
ko00310	Lysine degradation	4/1214	73/7206	0.00677931213905
ko05131	Shigellosis	5/1214	82/7206	0.00687538806168
ko00590	Arachidonic acid metabolism	2/1214	52/7206	0.00819137240543
ko05133	Pertussis	6/1214	87/7206	0.00917382204214
ko04622	RIG-I-like receptor signaling pathway	3/1214	62/7206	0.00936430927738
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1214	100/7206	0.00996092357556
ko05418	Fluid shear stress and atherosclerosis	17/1214	173/7206	0.0100790098442
ko05145	Toxoplasmosis	11/1214	126/7206	0.0114345884168
ko05166	HTLV-I infection	34/1214	292/7206	0.0133454444869
ko05206	MicroRNAs in cancer	18/1214	177/7206	0.014444190854
ko04217	Necroptosis	18/1214	178/7206	0.0145235967647
ko00562	Inositol phosphate metabolism	24/1214	89/7206	0.0147598436964
ko00630	Glyoxylate and dicarboxylate metabolism	1/1214	38/7206	0.0148121564933
ko04930	Type II diabetes mellitus	16/1214	54/7206	0.0169682031668
ko04115	p53 signaling pathway	5/1214	74/7206	0.0181217112163
ko04932	Non-alcoholic fatty liver disease (NAFLD)	19/1214	182/7206	0.0204905784044
ko04964	Proximal tubule bicarbonate reclamation	10/1214	29/7206	0.0210383347886
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1214	59/7206	0.021475726471
ko04626	Plant-pathogen interaction	7/1214	18/7206	0.0216766645262
ko00500	Starch and sucrose metabolism	1/1214	35/7206	0.0218793281721
ko04350	TGF-beta signaling pathway	9/1214	103/7206	0.023952987997
ko04710	Circadian rhythm	13/1214	43/7206	0.02459253146
ko05016	Huntington's disease	24/1214	215/7206	0.0258890732865
ko04658	Th1 and Th2 cell differentiation	8/1214	96/7206	0.0268595685686
ko05215	Prostate cancer	10/1214	111/7206	0.0287419383244
ko04922	Glucagon signaling pathway	31/1214	128/7206	0.0312547082814
ko04620	Toll-like receptor signaling pathway	9/1214	100/7206	0.0314657693135
ko04630	Jak-STAT signaling pathway	13/1214	132/7206	0.0336901596533
ko00860	Porphyrin and chlorophyll metabolism	1/1214	34/7206	0.0345630484155
ko00330	Arginine and proline metabolism	4/1214	61/7206	0.0369575245796
ko04722	Neurotrophin signaling pathway	37/1214	160/7206	0.0415679057802
ko01524	Platinum drug resistance	6/1214	76/7206	0.043296153956
ko04510	Focal adhesion	29/1214	240/7206	0.0437689918526
ko04140	Autophagy - animal	18/1214	164/7206	0.0444159289547
ko04668	TNF signaling pathway	12/1214	120/7206	0.0480951455158