ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/995	423/7206	7.56884688658e-39
ko05033	Nicotine addiction	46/995	56/7206	9.94382710471e-31
ko04724	Glutamatergic synapse	80/995	152/7206	1.58841458128e-30
ko05032	Morphine addiction	61/995	110/7206	4.14409737733e-25
ko04727	GABAergic synapse	60/995	110/7206	3.34927754286e-24
ko04728	Dopaminergic synapse	74/995	185/7206	3.63826216147e-19
ko04713	Circadian entrainment	61/995	136/7206	6.38795393737e-19
ko04723	Retrograde endocannabinoid signaling	71/995	175/7206	7.75818083622e-19
ko04725	Cholinergic synapse	66/995	160/7206	4.94906479268e-18
ko04024	cAMP signaling pathway	91/995	279/7206	2.07892828286e-16
ko04721	Synaptic vesicle cycle	41/995	80/7206	1.23671799708e-15
ko04744	Phototransduction	25/995	36/7206	3.18945181004e-14
ko04742	Taste transduction	33/995	61/7206	1.02349417343e-13
ko04726	Serotonergic synapse	50/995	137/7206	1.49522697585e-11
ko04911	Insulin secretion	45/995	117/7206	2.02024466831e-11
ko04921	Oxytocin signaling pathway	65/995	209/7206	6.27843435724e-11
ko04020	Calcium signaling pathway	76/995	265/7206	1.30969033442e-10
ko04720	Long-term potentiation	38/995	99/7206	8.095345106e-10
ko05031	Amphetamine addiction	36/995	91/7206	8.51461667266e-10
ko05203	Viral carcinogenesis	9/995	277/7206	2.48942697699e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/995	205/7206	6.21646398244e-09
ko03040	Spliceosome	1/995	145/7206	1.4396250482e-08
ko04360	Axon guidance	63/995	233/7206	6.11873523727e-08
ko04060	Cytokine-cytokine receptor interaction	5/995	191/7206	1.79582900939e-07
ko05030	Cocaine addiction	27/995	73/7206	5.57582689894e-07
ko05164	Influenza A	4/995	167/7206	5.95475422903e-07
ko04970	Salivary secretion	32/995	95/7206	6.03400642306e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/995	74/7206	2.79194719785e-06
ko05322	Systemic lupus erythematosus	4/995	151/7206	3.97970545018e-06
ko05168	Herpes simplex infection	7/995	182/7206	1.02390397267e-05
ko04141	Protein processing in endoplasmic reticulum	7/995	184/7206	1.05809352476e-05
ko03013	RNA transport	6/995	166/7206	1.84024494131e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/995	79/7206	1.84346723708e-05
ko04022	cGMP-PKG signaling pathway	53/995	216/7206	2.00071950949e-05
ko04925	Aldosterone synthesis and secretion	31/995	105/7206	2.23752758428e-05
ko05169	Epstein-Barr virus infection	10/995	206/7206	3.46073950116e-05
ko04260	Cardiac muscle contraction	29/995	98/7206	4.17924050168e-05
ko04971	Gastric acid secretion	29/995	98/7206	4.17924050168e-05
ko04010	MAPK signaling pathway	70/995	321/7206	6.30546908739e-05
ko04120	Ubiquitin mediated proteolysis	5/995	138/7206	9.30029737549e-05
ko04621	NOD-like receptor signaling pathway	7/995	157/7206	0.000159350685529
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/995	14/7206	0.000178169252206
ko03008	Ribosome biogenesis in eukaryotes	1/995	79/7206	0.000204901650466
ko04740	Olfactory transduction	24/995	80/7206	0.000216609426726
ko05162	Measles	4/995	120/7206	0.000241404514226
ko04730	Long-term depression	23/995	78/7206	0.000350204644342
ko04514	Cell adhesion molecules (CAMs)	33/995	130/7206	0.000427501146926
ko04972	Pancreatic secretion	29/995	111/7206	0.000454982372952
ko05205	Proteoglycans in cancer	19/995	271/7206	0.000591912726618
ko04924	Renin secretion	24/995	86/7206	0.000715683127395
ko05414	Dilated cardiomyopathy	29/995	112/7206	0.000739657579679
ko05161	Hepatitis B	10/995	173/7206	0.00109100410241
ko04745	Phototransduction - fly	13/995	38/7206	0.00116881672295
ko04612	Antigen processing and presentation	2/995	77/7206	0.00142181935554
ko04014	Ras signaling pathway	57/995	279/7206	0.00185531833202
ko05140	Leishmaniasis	2/995	75/7206	0.00208093005712
ko04110	Cell cycle	8/995	145/7206	0.00213323116893
ko04540	Gap junction	30/995	128/7206	0.00273738698065
ko04214	Apoptosis - fly	2/995	72/7206	0.0030339901475
ko04630	Jak-STAT signaling pathway	7/995	132/7206	0.00304092182637
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/995	182/7206	0.00306996949863
ko03018	RNA degradation	3/995	84/7206	0.00361983913921
ko05145	Toxoplasmosis	7/995	126/7206	0.00400153848627
ko04064	NF-kappa B signaling pathway	4/995	96/7206	0.00405013800679
ko00515	Mannose type O-glycan biosynthesis	9/995	25/7206	0.00450858920062
ko00480	Glutathione metabolism	1/995	55/7206	0.00504816757054
ko05321	Inflammatory bowel disease (IBD)	1/995	56/7206	0.00523805711553
ko04350	TGF-beta signaling pathway	5/995	103/7206	0.00567923701687
ko04140	Autophagy - animal	11/995	164/7206	0.00571055122259
ko04966	Collecting duct acid secretion	9/995	26/7206	0.00606632547033
ko04072	Phospholipase D signaling pathway	41/995	197/7206	0.0061742373188
ko00590	Arachidonic acid metabolism	1/995	52/7206	0.0075001987251
ko00240	Pyrimidine metabolism	6/995	110/7206	0.00764109101703
ko04657	IL-17 signaling pathway	4/995	87/7206	0.00764272198674
ko05215	Prostate cancer	6/995	111/7206	0.0077519988387
ko04146	Peroxisome	4/995	89/7206	0.00776005816172
ko04070	Phosphatidylinositol signaling system	26/995	112/7206	0.00795411957725
ko04640	Hematopoietic cell lineage	2/995	64/7206	0.00948907349062
ko04915	Estrogen signaling pathway	29/995	131/7206	0.00985249544266
ko00260	Glycine, serine and threonine metabolism	1/995	48/7206	0.0110150068478
ko05219	Bladder cancer	1/995	48/7206	0.0110150068478
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/995	15/7206	0.0112406365102
ko05410	Hypertrophic cardiomyopathy (HCM)	23/995	100/7206	0.0121523012758
ko04964	Proximal tubule bicarbonate reclamation	9/995	29/7206	0.0132606333568
ko04976	Bile secretion	19/995	80/7206	0.0139791059297
ko05131	Shigellosis	4/995	82/7206	0.0148580305061
ko04137	Mitophagy - animal	4/995	82/7206	0.0148580305061
ko05144	Malaria	1/995	45/7206	0.0163256294679
ko00071	Fatty acid degradation	1/995	45/7206	0.0163256294679
ko03420	Nucleotide excision repair	1/995	46/7206	0.0164833864013
ko04670	Leukocyte transendothelial migration	11/995	151/7206	0.0166617550736
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/995	26/7206	0.0201867847642
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/995	59/7206	0.0205068734851
ko04668	TNF signaling pathway	8/995	120/7206	0.022267079336
ko03022	Basal transcription factors	1/995	44/7206	0.0251336954022
ko04371	Apelin signaling pathway	35/995	177/7206	0.0266246003914
ko01524	Platinum drug resistance	4/995	76/7206	0.0284500821431
ko04210	Apoptosis	15/995	180/7206	0.0285531921204
ko05166	HTLV-I infection	28/995	292/7206	0.0304930483313
ko04510	Focal adhesion	22/995	240/7206	0.0357647431866
ko05206	MicroRNAs in cancer	15/995	177/7206	0.0358785399914
ko00980	Metabolism of xenobiotics by cytochrome P450	1/995	40/7206	0.0359726014414
ko00330	Arginine and proline metabolism	3/995	61/7206	0.0399851974454
ko04622	RIG-I-like receptor signaling pathway	3/995	62/7206	0.0402364095519
ko00561	Glycerolipid metabolism	3/995	63/7206	0.0410067338047
ko00600	Sphingolipid metabolism	3/995	63/7206	0.0410067338047
ko04930	Type II diabetes mellitus	13/995	54/7206	0.0441332681588
ko04923	Regulation of lipolysis in adipocytes	17/995	77/7206	0.044587476416
ko05418	Fluid shear stress and atherosclerosis	15/995	173/7206	0.0449333889361
ko04750	Inflammatory mediator regulation of TRP channels	25/995	122/7206	0.0455924335368