ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/262 191/7206 1.15643402601e-12 ko04650 Natural killer cell mediated cytotoxicity 20/262 97/7206 1.75134828093e-10 ko05340 Primary immunodeficiency 12/262 30/7206 2.00675996049e-10 ko04380 Osteoclast differentiation 20/262 134/7206 6.1677071121e-08 ko05330 Allograft rejection 9/262 24/7206 7.8456260831e-08 ko04612 Antigen processing and presentation 15/262 77/7206 8.02726263672e-08 ko04659 Th17 cell differentiation 17/262 106/7206 2.15398569728e-07 ko04640 Hematopoietic cell lineage 13/262 64/7206 3.60593077043e-07 ko05320 Autoimmune thyroid disease 9/262 29/7206 5.12021520055e-07 ko05162 Measles 17/262 120/7206 1.32495989443e-06 ko05332 Graft-versus-host disease 7/262 18/7206 1.75009440075e-06 ko05152 Tuberculosis 21/262 187/7206 3.67754203522e-06 ko04658 Th1 and Th2 cell differentiation 14/262 96/7206 8.24507165175e-06 ko04660 T cell receptor signaling pathway 16/262 124/7206 9.42064875439e-06 ko05321 Inflammatory bowel disease (IBD) 10/262 56/7206 2.76033272778e-05 ko05164 Influenza A 18/262 167/7206 3.25190074685e-05 ko05150 Staphylococcus aureus infection 8/262 36/7206 3.42467493061e-05 ko04672 Intestinal immune network for IgA production 8/262 37/7206 4.23356126519e-05 ko05145 Toxoplasmosis 15/262 126/7206 4.72620391052e-05 ko05140 Leishmaniasis 11/262 75/7206 7.37881902202e-05 ko04630 Jak-STAT signaling pathway 15/262 132/7206 8.13616020055e-05 ko05168 Herpes simplex infection 18/262 182/7206 0.00010150598535 ko04940 Type I diabetes mellitus 7/262 32/7206 0.000119502666128 ko04145 Phagosome 16/262 162/7206 0.000250733458813 ko05310 Asthma 5/262 17/7206 0.000264149709137 ko04062 Chemokine signaling pathway 18/262 201/7206 0.000354518465099 ko04621 NOD-like receptor signaling pathway 15/262 157/7206 0.000557056746102 ko03050 Proteasome 8/262 54/7206 0.000668114426018 ko04217 Necroptosis 16/262 178/7206 0.000721204227663 ko04620 Toll-like receptor signaling pathway 11/262 100/7206 0.000955851186219 ko04666 Fc gamma R-mediated phagocytosis 12/262 122/7206 0.00153170618651 ko04664 Fc epsilon RI signaling pathway 9/262 77/7206 0.00179295291189 ko05034 Alcoholism 1/262 238/7206 0.0023331137634 ko04064 NF-kappa B signaling pathway 10/262 96/7206 0.00243897030979 ko00590 Arachidonic acid metabolism 7/262 52/7206 0.00255536202022 ko05416 Viral myocarditis 7/262 55/7206 0.00353386925454 ko00051 Fructose and mannose metabolism 6/262 42/7206 0.00380577219866 ko05133 Pertussis 9/262 87/7206 0.00416066376498 ko00120 Primary bile acid biosynthesis 4/262 20/7206 0.00522176569533 ko05144 Malaria 6/262 45/7206 0.00539676341589 ko04622 RIG-I-like receptor signaling pathway 7/262 62/7206 0.00690734495186 ko05142 Chagas disease (American trypanosomiasis) 11/262 130/7206 0.00753172626656 ko04514 Cell adhesion molecules (CAMs) 11/262 130/7206 0.00753172626656 ko04610 Complement and coagulation cascades 8/262 79/7206 0.00767934820717 ko04611 Platelet activation 13/262 163/7206 0.00850102242899 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/262 191/7206 0.0103731469917 ko00511 Other glycan degradation 4/262 26/7206 0.0135858984479 ko04662 B cell receptor signaling pathway 8/262 88/7206 0.0143209813336 ko04310 Wnt signaling pathway 1/262 181/7206 0.0150807283323 ko04728 Dopaminergic synapse 1/262 185/7206 0.0152238427081 ko05323 Rheumatoid arthritis 8/262 89/7206 0.0152571714252 ko04723 Retrograde endocannabinoid signaling 1/262 175/7206 0.0221098364945 ko05202 Transcriptional misregulation in cancer 13/262 188/7206 0.0264049028652 ko04137 Mitophagy - animal 7/262 82/7206 0.0290367535528 ko00592 alpha-Linolenic acid metabolism 3/262 19/7206 0.0299201026725 ko03013 RNA transport 1/262 166/7206 0.0323285441355 ko05161 Hepatitis B 12/262 173/7206 0.0352381541797 ko00480 Glutathione metabolism 5/262 55/7206 0.0486116601628 ko04360 Axon guidance 3/262 233/7206 0.0492330943256