ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/267 191/7206 3.3238902134e-13 ko05340 Primary immunodeficiency 14/267 30/7206 5.61111229224e-13 ko04650 Natural killer cell mediated cytotoxicity 19/267 97/7206 1.76297587804e-09 ko04612 Antigen processing and presentation 17/267 77/7206 1.87143395123e-09 ko05330 Allograft rejection 10/267 24/7206 5.11524060512e-09 ko05164 Influenza A 24/267 167/7206 8.76196805885e-09 ko05152 Tuberculosis 25/267 187/7206 1.90052519377e-08 ko05320 Autoimmune thyroid disease 10/267 29/7206 4.43130818562e-08 ko04659 Th17 cell differentiation 18/267 106/7206 5.0266968676e-08 ko05140 Leishmaniasis 15/267 75/7206 7.11951999106e-08 ko05332 Graft-versus-host disease 8/267 18/7206 1.01465889479e-07 ko05162 Measles 18/267 120/7206 3.54400263237e-07 ko05321 Inflammatory bowel disease (IBD) 12/267 56/7206 6.81235795521e-07 ko05145 Toxoplasmosis 18/267 126/7206 7.4638172261e-07 ko04145 Phagosome 20/267 162/7206 1.92833895199e-06 ko04658 Th1 and Th2 cell differentiation 15/267 96/7206 2.02779311935e-06 ko05168 Herpes simplex infection 21/267 182/7206 3.21032176882e-06 ko05150 Staphylococcus aureus infection 9/267 36/7206 4.49491532155e-06 ko04672 Intestinal immune network for IgA production 9/267 37/7206 5.74929735794e-06 ko04380 Osteoclast differentiation 17/267 134/7206 8.01693350519e-06 ko04660 T cell receptor signaling pathway 16/267 124/7206 1.19636518207e-05 ko04940 Type I diabetes mellitus 8/267 32/7206 1.55091125178e-05 ko05310 Asthma 6/267 17/7206 2.14514850418e-05 ko04630 Jak-STAT signaling pathway 16/267 132/7206 2.65579103975e-05 ko04610 Complement and coagulation cascades 12/267 79/7206 2.91949713048e-05 ko04217 Necroptosis 19/267 178/7206 2.92700392435e-05 ko04621 NOD-like receptor signaling pathway 17/267 157/7206 6.45769555804e-05 ko05133 Pertussis 12/267 87/7206 7.76536119847e-05 ko04640 Hematopoietic cell lineage 10/267 64/7206 0.000106374026153 ko03050 Proteasome 9/267 54/7206 0.000141443220088 ko04064 NF-kappa B signaling pathway 12/267 96/7206 0.000203291741816 ko04620 Toll-like receptor signaling pathway 12/267 100/7206 0.000299671467108 ko04062 Chemokine signaling pathway 18/267 201/7206 0.000445586601883 ko00590 Arachidonic acid metabolism 8/267 52/7206 0.000583458187608 ko05416 Viral myocarditis 8/267 55/7206 0.000857615935222 ko04514 Cell adhesion molecules (CAMs) 13/267 130/7206 0.00100449141348 ko05144 Malaria 7/267 45/7206 0.00120171576675 ko04360 Axon guidance 1/267 233/7206 0.00232943133739 ko05034 Alcoholism 1/267 238/7206 0.00239854575554 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/267 191/7206 0.00253094126182 ko04611 Platelet activation 14/267 163/7206 0.00280981620999 ko00051 Fructose and mannose metabolism 6/267 42/7206 0.00417645129708 ko05323 Rheumatoid arthritis 9/267 89/7206 0.00547349167197 ko00120 Primary bile acid biosynthesis 4/267 20/7206 0.00558402262063 ko04664 Fc epsilon RI signaling pathway 8/267 77/7206 0.00736129653547 ko04390 Hippo signaling pathway 1/267 188/7206 0.0104171033376 ko04310 Wnt signaling pathway 1/267 181/7206 0.015173166058 ko00980 Metabolism of xenobiotics by cytochrome P450 5/267 40/7206 0.015324393671 ko04728 Dopaminergic synapse 1/267 185/7206 0.0156177601061 ko04662 B cell receptor signaling pathway 8/267 88/7206 0.0158927985464 ko04080 Neuroactive ligand-receptor interaction 7/267 423/7206 0.0166300877477 ko04530 Tight junction 2/267 228/7206 0.0184245167196 ko03013 RNA transport 1/267 166/7206 0.0217719707296 ko04910 Insulin signaling pathway 1/267 172/7206 0.0221336396385 ko05224 Breast cancer 1/267 174/7206 0.0224951505424 ko05132 Salmonella infection 8/267 98/7206 0.0284340778497 ko05202 Transcriptional misregulation in cancer 13/267 188/7206 0.0284671693959 ko05142 Chagas disease (American trypanosomiasis) 10/267 130/7206 0.0292041743092 ko00592 alpha-Linolenic acid metabolism 3/267 19/7206 0.0314106192034 ko05204 Chemical carcinogenesis 5/267 48/7206 0.0314421007739 ko04137 Mitophagy - animal 7/267 82/7206 0.0317359307862 ko04510 Focal adhesion 3/267 240/7206 0.0359657822711 ko00966 Glucosinolate biosynthesis 1/267 1/7206 0.0370524562864 ko03040 Spliceosome 1/267 145/7206 0.0450358849232 ko04110 Cell cycle 1/267 145/7206 0.0450358849232 ko04666 Fc gamma R-mediated phagocytosis 9/267 122/7206 0.0464105442678 ko00982 Drug metabolism - cytochrome P450 4/267 37/7206 0.0466915829229