ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	177/847	423/7206	2.54350634243e-60
ko05033	Nicotine addiction	49/847	56/7206	8.10824407027e-39
ko04724	Glutamatergic synapse	79/847	152/7206	1.07882889877e-34
ko04727	GABAergic synapse	57/847	110/7206	3.70667763859e-25
ko05032	Morphine addiction	57/847	110/7206	3.70667763859e-25
ko04713	Circadian entrainment	64/847	136/7206	4.36718225703e-25
ko04723	Retrograde endocannabinoid signaling	68/847	175/7206	9.07505536015e-21
ko04728	Dopaminergic synapse	70/847	185/7206	1.40107960993e-20
ko04725	Cholinergic synapse	62/847	160/7206	5.97877850591e-19
ko04024	cAMP signaling pathway	87/847	279/7206	6.82459694955e-19
ko04911	Insulin secretion	48/847	117/7206	4.35849417924e-16
ko04020	Calcium signaling pathway	79/847	265/7206	5.68321350259e-16
ko04721	Synaptic vesicle cycle	38/847	80/7206	1.60366731095e-15
ko05031	Amphetamine addiction	38/847	91/7206	2.75706754524e-13
ko04921	Oxytocin signaling pathway	63/847	209/7206	3.4799207318e-13
ko04742	Taste transduction	30/847	61/7206	5.03010999162e-13
ko04726	Serotonergic synapse	48/847	137/7206	5.55017794141e-13
ko04720	Long-term potentiation	37/847	99/7206	3.03457928277e-11
ko04261	Adrenergic signaling in cardiomyocytes	57/847	205/7206	1.77525985155e-10
ko04740	Olfactory transduction	31/847	80/7206	4.30831204715e-10
ko04970	Salivary secretion	34/847	95/7206	7.49396821114e-10
ko05030	Cocaine addiction	28/847	73/7206	3.99236539754e-09
ko04971	Gastric acid secretion	33/847	98/7206	7.90747367872e-09
ko04744	Phototransduction	18/847	36/7206	1.77373374486e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/847	74/7206	2.66144020509e-08
ko04925	Aldosterone synthesis and secretion	33/847	105/7206	5.39959915433e-08
ko05164	Influenza A	2/847	167/7206	3.10090661852e-07
ko03040	Spliceosome	1/847	145/7206	3.50614397603e-07
ko04010	MAPK signaling pathway	67/847	321/7206	1.92229602841e-06
ko05203	Viral carcinogenesis	10/847	277/7206	2.21260420316e-06
ko04060	Cytokine-cytokine receptor interaction	5/847	191/7206	6.2806577571e-06
ko04972	Pancreatic secretion	30/847	111/7206	8.14820895673e-06
ko05162	Measles	1/847	120/7206	9.57804603276e-06
ko04745	Phototransduction - fly	15/847	38/7206	1.1297216597e-05
ko04260	Cardiac muscle contraction	27/847	98/7206	1.85595174956e-05
ko05168	Herpes simplex infection	5/847	182/7206	1.9047748683e-05
ko04022	cGMP-PKG signaling pathway	46/847	216/7206	5.63400553571e-05
ko04730	Long-term depression	22/847	78/7206	5.92424445915e-05
ko04120	Ubiquitin mediated proteolysis	3/847	138/7206	7.60159024598e-05
ko04514	Cell adhesion molecules (CAMs)	31/847	130/7206	8.81241168496e-05
ko05322	Systemic lupus erythematosus	4/847	151/7206	9.4606084542e-05
ko05169	Epstein-Barr virus infection	8/847	206/7206	0.00010082499395
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/847	79/7206	0.000121593287864
ko04750	Inflammatory mediator regulation of TRP channels	29/847	122/7206	0.000166731302895
ko03013	RNA transport	6/847	166/7206	0.000338865013344
ko04540	Gap junction	29/847	128/7206	0.000424596599592
ko04110	Cell cycle	5/847	145/7206	0.000608638868009
ko04621	NOD-like receptor signaling pathway	6/847	157/7206	0.000650161472718
ko04141	Protein processing in endoplasmic reticulum	8/847	184/7206	0.000684638807632
ko05205	Proteoglycans in cancer	15/847	271/7206	0.000693430462251
ko05215	Prostate cancer	3/847	111/7206	0.000945838656716
ko04072	Phospholipase D signaling pathway	39/847	197/7206	0.00100811647119
ko04612	Antigen processing and presentation	1/847	77/7206	0.00113585525741
ko04964	Proximal tubule bicarbonate reclamation	10/847	29/7206	0.00117319106843
ko04610	Complement and coagulation cascades	1/847	79/7206	0.00117503784237
ko03008	Ribosome biogenesis in eukaryotes	1/847	79/7206	0.00117503784237
ko04976	Bile secretion	20/847	80/7206	0.00122957268997
ko04550	Signaling pathways regulating pluripotency of stem cells	7/847	165/7206	0.00129574063811
ko05166	HTLV-I infection	18/847	292/7206	0.00153014288555
ko05414	Dilated cardiomyopathy	25/847	112/7206	0.00154849109194
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/847	59/7206	0.00155223206383
ko04924	Renin secretion	20/847	86/7206	0.00214931595427
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/847	182/7206	0.00225925730894
ko04150	mTOR signaling pathway	9/847	184/7206	0.00232168791253
ko04630	Jak-STAT signaling pathway	5/847	132/7206	0.002357974573
ko04214	Apoptosis - fly	1/847	72/7206	0.00257306224663
ko04218	Cellular senescence	9/847	177/7206	0.00302408232467
ko04210	Apoptosis	9/847	180/7206	0.00309132919958
ko04140	Autophagy - animal	8/847	164/7206	0.00436988555854
ko04360	Axon guidance	42/847	233/7206	0.00492674499334
ko05161	Hepatitis B	9/847	173/7206	0.00553709705945
ko04510	Focal adhesion	15/847	240/7206	0.00564705883319
ko04070	Phosphatidylinositol signaling system	23/847	112/7206	0.00702446763216
ko04350	TGF-beta signaling pathway	4/847	103/7206	0.00829405663616
ko04330	Notch signaling pathway	1/847	62/7206	0.00840779082088
ko00310	Lysine degradation	2/847	73/7206	0.0100206430003
ko04912	GnRH signaling pathway	24/847	122/7206	0.0100480003647
ko04014	Ras signaling pathway	47/847	279/7206	0.0101551236468
ko04146	Peroxisome	3/847	89/7206	0.0115910029361
ko04626	Plant-pathogen interaction	6/847	18/7206	0.0138280371208
ko00240	Pyrimidine metabolism	5/847	110/7206	0.0158957778189
ko05220	Chronic myeloid leukemia	3/847	85/7206	0.0160714780409
ko05410	Hypertrophic cardiomyopathy (HCM)	20/847	100/7206	0.0174864428641
ko00480	Glutathione metabolism	1/847	55/7206	0.0181719841765
ko05200	Pathways in cancer	42/847	492/7206	0.0202390539587
ko04668	TNF signaling pathway	6/847	120/7206	0.0208783857516
ko04142	Lysosome	9/847	151/7206	0.0214080169519
ko04978	Mineral absorption	10/847	40/7206	0.0216509352548
ko04960	Aldosterone-regulated sodium reabsorption	10/847	41/7206	0.0236845833669
ko04966	Collecting duct acid secretion	7/847	26/7206	0.0267474757407
ko04915	Estrogen signaling pathway	24/847	131/7206	0.0271788397098
ko04918	Thyroid hormone synthesis	17/847	86/7206	0.0274426335982
ko04640	Hematopoietic cell lineage	2/847	64/7206	0.0297324784557
ko04930	Type II diabetes mellitus	12/847	54/7206	0.0300211848181
ko05222	Small cell lung cancer	4/847	89/7206	0.0301274366643
ko05231	Choline metabolism in cancer	24/847	134/7206	0.0302121035961
ko05140	Leishmaniasis	3/847	75/7206	0.0303912636284
ko01524	Platinum drug resistance	3/847	76/7206	0.0304557314495
ko00620	Pyruvate metabolism	1/847	46/7206	0.0377413841442
ko03420	Nucleotide excision repair	1/847	46/7206	0.0377413841442
ko04068	FoxO signaling pathway	11/847	167/7206	0.0378041625221
ko00260	Glycine, serine and threonine metabolism	1/847	48/7206	0.0390190806292
ko03018	RNA degradation	4/847	84/7206	0.0410057866696
ko01212	Fatty acid metabolism	2/847	60/7206	0.0419456095489
ko04657	IL-17 signaling pathway	4/847	87/7206	0.0420870189445