ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 8/387 20/7206 4.58529155215e-06 ko04710 Circadian rhythm 11/387 43/7206 1.12600366727e-05 ko04137 Mitophagy - animal 15/387 82/7206 2.47789071302e-05 ko04630 Jak-STAT signaling pathway 19/387 132/7206 7.1899190591e-05 ko04060 Cytokine-cytokine receptor interaction 24/387 191/7206 0.000102567806018 ko04146 Peroxisome 14/387 89/7206 0.000249644834165 ko00592 alpha-Linolenic acid metabolism 6/387 19/7206 0.000344317815669 ko00590 Arachidonic acid metabolism 9/387 52/7206 0.00159050697318 ko04621 NOD-like receptor signaling pathway 18/387 157/7206 0.0019624923343 ko03013 RNA transport 1/387 166/7206 0.0023892075585 ko05150 Staphylococcus aureus infection 7/387 36/7206 0.00262877426151 ko04380 Osteoclast differentiation 16/387 134/7206 0.00267211043698 ko00982 Drug metabolism - cytochrome P450 7/387 37/7206 0.00309566485156 ko04068 FoxO signaling pathway 18/387 167/7206 0.00452378138293 ko05164 Influenza A 18/387 167/7206 0.00452378138293 ko03040 Spliceosome 1/387 145/7206 0.00477517090128 ko04658 Th1 and Th2 cell differentiation 12/387 96/7206 0.00506189305032 ko04064 NF-kappa B signaling pathway 12/387 96/7206 0.00506189305032 ko04650 Natural killer cell mediated cytotoxicity 12/387 97/7206 0.0055050989121 ko00983 Drug metabolism - other enzymes 7/387 42/7206 0.00644171443733 ko00051 Fructose and mannose metabolism 7/387 42/7206 0.00644171443733 ko05140 Leishmaniasis 10/387 75/7206 0.00644831802668 ko04611 Platelet activation 17/387 163/7206 0.00753235902899 ko05034 Alcoholism 4/387 238/7206 0.00760792728105 ko05145 Toxoplasmosis 14/387 126/7206 0.00831613801298 ko00480 Glutathione metabolism 8/387 55/7206 0.00852159792185 ko05321 Inflammatory bowel disease (IBD) 8/387 56/7206 0.0094902352337 ko04217 Necroptosis 18/387 178/7206 0.0100540377651 ko00564 Glycerophospholipid metabolism 12/387 99/7206 0.0105564374838 ko04672 Intestinal immune network for IgA production 6/387 37/7206 0.013025361573 ko05204 Chemical carcinogenesis 7/387 48/7206 0.0133513874154 ko03010 Ribosome 1/387 129/7206 0.0154844058554 ko02010 ABC transporters 6/387 39/7206 0.0167103060987 ko00980 Metabolism of xenobiotics by cytochrome P450 6/387 40/7206 0.0187978333788 ko05340 Primary immunodeficiency 5/387 30/7206 0.0204277789054 ko00140 Steroid hormone biosynthesis 6/387 41/7206 0.0210567341559 ko04960 Aldosterone-regulated sodium reabsorption 6/387 41/7206 0.0210567341559 ko04136 Autophagy - other 5/387 31/7206 0.0233162929406 ko04930 Type II diabetes mellitus 7/387 54/7206 0.024429866822 ko04110 Cell cycle 2/387 145/7206 0.0244593801182 ko04659 Th17 cell differentiation 11/387 106/7206 0.0291224681893 ko04711 Circadian rhythm - fly 3/387 13/7206 0.0293926398844 ko00052 Galactose metabolism 5/387 33/7206 0.0298535168621 ko03320 PPAR signaling pathway 8/387 69/7206 0.0306355209672 ko04152 AMPK signaling pathway 15/387 161/7206 0.0325648026976 ko04080 Neuroactive ligand-receptor interaction 13/387 423/7206 0.0336762295259 ko04668 TNF signaling pathway 12/387 120/7206 0.0370344219166 ko00220 Arginine biosynthesis 4/387 24/7206 0.0370854344801 ko00362 Benzoate degradation 2/387 6/7206 0.0373659389082 ko00500 Starch and sucrose metabolism 5/387 35/7206 0.0374407252463 ko04211 Longevity regulating pathway 12/387 123/7206 0.0406344418859 ko04670 Leukocyte transendothelial migration 14/387 151/7206 0.0423019153433 ko04520 Adherens junction 1/387 103/7206 0.0443798701162 ko05168 Herpes simplex infection 16/387 182/7206 0.0449846767022 ko04932 Non-alcoholic fatty liver disease (NAFLD) 16/387 182/7206 0.0449846767022 ko04390 Hippo signaling pathway 4/387 188/7206 0.0472116908221 ko04622 RIG-I-like receptor signaling pathway 7/387 62/7206 0.0472427171026 ko04540 Gap junction 2/387 128/7206 0.0479699091222 ko04213 Longevity regulating pathway - multiple species 9/387 86/7206 0.0487948341329