ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/902	423/7206	3.21972807033e-39
ko04724	Glutamatergic synapse	72/902	152/7206	1.35606384777e-26
ko04721	Synaptic vesicle cycle	48/902	80/7206	6.41192466689e-24
ko05033	Nicotine addiction	39/902	56/7206	3.58544700023e-23
ko05032	Morphine addiction	53/902	110/7206	2.90325350048e-20
ko04727	GABAergic synapse	52/902	110/7206	1.96212749024e-19
ko04728	Dopaminergic synapse	68/902	185/7206	1.01953868132e-17
ko04713	Circadian entrainment	55/902	136/7206	1.12846645344e-16
ko04723	Retrograde endocannabinoid signaling	62/902	175/7206	2.30163533773e-15
ko04725	Cholinergic synapse	57/902	160/7206	2.44729401943e-14
ko04024	cAMP signaling pathway	80/902	279/7206	1.73988463132e-13
ko04742	Taste transduction	31/902	61/7206	3.64280932934e-13
ko04911	Insulin secretion	44/902	117/7206	2.81639764311e-12
ko04726	Serotonergic synapse	48/902	137/7206	5.81298400378e-12
ko04921	Oxytocin signaling pathway	60/902	209/7206	1.96143118701e-10
ko04261	Adrenergic signaling in cardiomyocytes	58/902	205/7206	1.08300523191e-09
ko05031	Amphetamine addiction	32/902	91/7206	1.87404719622e-08
ko04020	Calcium signaling pathway	65/902	265/7206	4.15483024596e-08
ko03040	Spliceosome	1/902	145/7206	1.47026804635e-07
ko04720	Long-term potentiation	32/902	99/7206	1.8112183634e-07
ko04966	Collecting duct acid secretion	14/902	26/7206	4.7337941779e-07
ko04970	Salivary secretion	30/902	95/7206	7.69920568063e-07
ko05203	Viral carcinogenesis	11/902	277/7206	1.07706648927e-06
ko05030	Cocaine addiction	25/902	73/7206	1.19742043423e-06
ko04744	Phototransduction	16/902	36/7206	2.02454029949e-06
ko04514	Cell adhesion molecules (CAMs)	36/902	130/7206	2.65676071705e-06
ko05168	Herpes simplex infection	5/902	182/7206	4.05481972798e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/902	74/7206	5.81254305772e-06
ko04260	Cardiac muscle contraction	29/902	98/7206	6.94797513018e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/902	79/7206	2.02775183688e-05
ko04120	Ubiquitin mediated proteolysis	3/902	138/7206	2.21733209761e-05
ko03013	RNA transport	5/902	166/7206	2.48052555876e-05
ko04010	MAPK signaling pathway	66/902	321/7206	2.99194578898e-05
ko04060	Cytokine-cytokine receptor interaction	7/902	191/7206	3.24666420008e-05
ko04925	Aldosterone synthesis and secretion	29/902	105/7206	3.38630988934e-05
ko05110	Vibrio cholerae infection	20/902	63/7206	4.89485952496e-05
ko04360	Axon guidance	50/902	233/7206	0.000109276382311
ko05164	Influenza A	6/902	167/7206	0.00011950411574
ko05322	Systemic lupus erythematosus	5/902	151/7206	0.000149589084403
ko05162	Measles	3/902	120/7206	0.000219873809385
ko05414	Dilated cardiomyopathy	28/902	112/7206	0.000246665158697
ko04141	Protein processing in endoplasmic reticulum	8/902	184/7206	0.000255759994044
ko04621	NOD-like receptor signaling pathway	6/902	157/7206	0.000330775396858
ko05205	Proteoglycans in cancer	16/902	271/7206	0.000350877566532
ko04924	Renin secretion	23/902	86/7206	0.000386654915993
ko03008	Ribosome biogenesis in eukaryotes	1/902	79/7206	0.000489017352566
ko04022	cGMP-PKG signaling pathway	45/902	216/7206	0.000500914822679
ko04971	Gastric acid secretion	25/902	98/7206	0.000531081818305
ko04540	Gap junction	30/902	128/7206	0.000605176129496
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/902	14/7206	0.000726521013597
ko04612	Antigen processing and presentation	1/902	77/7206	0.000742583728576
ko04214	Apoptosis - fly	1/902	72/7206	0.001089799235
ko04972	Pancreatic secretion	26/902	111/7206	0.00125640983606
ko04730	Long-term depression	20/902	78/7206	0.00148670859365
ko05169	Epstein-Barr virus infection	12/902	206/7206	0.00184956187365
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/902	92/7206	0.00221315362506
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/902	59/7206	0.00222149482911
ko05161	Hepatitis B	9/902	173/7206	0.00224935321593
ko05410	Hypertrophic cardiomyopathy (HCM)	23/902	100/7206	0.0033185535425
ko05166	HTLV-I infection	21/902	292/7206	0.00373336789724
ko04140	Autophagy - animal	9/902	164/7206	0.00391834342439
ko05140	Leishmaniasis	2/902	75/7206	0.00467406112138
ko04740	Olfactory transduction	19/902	80/7206	0.00554250974702
ko00310	Lysine degradation	2/902	73/7206	0.00680041174517
ko04964	Proximal tubule bicarbonate reclamation	9/902	29/7206	0.00704737395822
ko04014	Ras signaling pathway	50/902	279/7206	0.00732698366559
ko04110	Cell cycle	8/902	145/7206	0.00738366214536
ko04915	Estrogen signaling pathway	27/902	131/7206	0.00739487175724
ko04630	Jak-STAT signaling pathway	7/902	132/7206	0.00775058444309
ko04064	NF-kappa B signaling pathway	4/902	96/7206	0.00805155809338
ko00240	Pyrimidine metabolism	5/902	110/7206	0.00824519498012
ko04976	Bile secretion	18/902	80/7206	0.0104535886446
ko00480	Glutathione metabolism	1/902	55/7206	0.0120412243109
ko04750	Inflammatory mediator regulation of TRP channels	25/902	122/7206	0.0121307395349
ko04146	Peroxisome	4/902	89/7206	0.0155168592977
ko04145	Phagosome	31/902	162/7206	0.0155567230249
ko04371	Apelin signaling pathway	33/902	177/7206	0.0157059785895
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/902	135/7206	0.0173978064784
ko00590	Arachidonic acid metabolism	1/902	52/7206	0.0179379592702
ko04626	Plant-pathogen interaction	6/902	18/7206	0.0185493578693
ko05215	Prostate cancer	6/902	111/7206	0.0198996705391
ko00561	Glycerolipid metabolism	2/902	63/7206	0.0201971290866
ko00190	Oxidative phosphorylation	25/902	127/7206	0.0204237217725
ko04640	Hematopoietic cell lineage	2/902	64/7206	0.0206260966143
ko04115	p53 signaling pathway	3/902	74/7206	0.0212681418895
ko04745	Phototransduction - fly	10/902	38/7206	0.0219785372616
ko05323	Rheumatoid arthritis	19/902	89/7206	0.0222552502634
ko00512	Mucin type O-glycan biosynthesis	8/902	29/7206	0.0225224527191
ko00620	Pyruvate metabolism	1/902	46/7206	0.0251811913534
ko03420	Nucleotide excision repair	1/902	46/7206	0.0251811913534
ko05219	Bladder cancer	1/902	48/7206	0.0257402257723
ko04962	Vasopressin-regulated water reabsorption	13/902	58/7206	0.0285081113719
ko03018	RNA degradation	4/902	84/7206	0.0296109123752
ko00330	Arginine and proline metabolism	2/902	61/7206	0.0297412692813
ko01200	Carbon metabolism	8/902	128/7206	0.0301303025594
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/902	15/7206	0.0310895381995
ko04923	Regulation of lipolysis in adipocytes	16/902	77/7206	0.0362847088496
ko03022	Basal transcription factors	1/902	44/7206	0.0372334063404
ko05206	MicroRNAs in cancer	13/902	177/7206	0.0375581155945
ko04218	Cellular senescence	13/902	177/7206	0.0375581155945
ko04217	Necroptosis	13/902	178/7206	0.0379325168334
ko00071	Fatty acid degradation	1/902	45/7206	0.0381253159004
ko04137	Mitophagy - animal	4/902	82/7206	0.0415626754744
ko04611	Platelet activation	12/902	163/7206	0.0418749376932
ko05418	Fluid shear stress and atherosclerosis	13/902	173/7206	0.0471947109976
ko04072	Phospholipase D signaling pathway	34/902	197/7206	0.0487571311889