ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04020	Calcium signaling pathway	80/1061	265/7206	6.85318428735e-11
ko03010	Ribosome	1/1061	129/7206	4.57145638971e-08
ko04080	Neuroactive ligand-receptor interaction	103/1061	423/7206	8.39996863688e-08
ko04713	Circadian entrainment	44/1061	136/7206	1.39328884279e-07
ko03040	Spliceosome	3/1061	145/7206	3.56005642907e-07
ko04024	cAMP signaling pathway	72/1061	279/7206	7.01640270719e-07
ko05322	Systemic lupus erythematosus	4/1061	151/7206	1.14480925791e-06
ko04710	Circadian rhythm	19/1061	43/7206	3.14108532061e-06
ko03013	RNA transport	6/1061	166/7206	3.93417900328e-06
ko04727	GABAergic synapse	35/1061	110/7206	4.3102950454e-06
ko05033	Nicotine addiction	22/1061	56/7206	5.70390892991e-06
ko04922	Glucagon signaling pathway	39/1061	128/7206	6.10827809735e-06
ko05203	Viral carcinogenesis	17/1061	277/7206	8.59397931937e-06
ko04724	Glutamatergic synapse	43/1061	152/7206	1.29436397517e-05
ko04110	Cell cycle	5/1061	145/7206	1.4175770588e-05
ko05032	Morphine addiction	34/1061	110/7206	1.51620949255e-05
ko04921	Oxytocin signaling pathway	54/1061	209/7206	2.47978297853e-05
ko04146	Peroxisome	29/1061	89/7206	2.6082054335e-05
ko00120	Primary bile acid biosynthesis	11/1061	20/7206	3.12810014933e-05
ko04022	cGMP-PKG signaling pathway	54/1061	216/7206	5.39846770313e-05
ko04911	Insulin secretion	34/1061	117/7206	5.66994456036e-05
ko01200	Carbon metabolism	36/1061	128/7206	7.31062528817e-05
ko04925	Aldosterone synthesis and secretion	31/1061	105/7206	7.90032745289e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1061	79/7206	8.20880303538e-05
ko04745	Phototransduction - fly	15/1061	38/7206	0.000165374033667
ko04657	IL-17 signaling pathway	2/1061	87/7206	0.000193899460958
ko04970	Salivary secretion	28/1061	95/7206	0.000197297010873
ko04514	Cell adhesion molecules (CAMs)	35/1061	130/7206	0.000243699448638
ko05031	Amphetamine addiction	27/1061	91/7206	0.000249996184212
ko00360	Phenylalanine metabolism	9/1061	17/7206	0.000250051861336
ko04744	Phototransduction	14/1061	36/7206	0.000327287141997
ko00071	Fatty acid degradation	16/1061	45/7206	0.000415469552315
ko00350	Tyrosine metabolism	13/1061	33/7206	0.000459813329019
ko00620	Pyruvate metabolism	16/1061	46/7206	0.000551355924744
ko00010	Glycolysis / Gluconeogenesis	22/1061	74/7206	0.000788393362702
ko00380	Tryptophan metabolism	17/1061	50/7206	0.000843864793468
ko03320	PPAR signaling pathway	21/1061	69/7206	0.000851061948309
ko04725	Cholinergic synapse	39/1061	160/7206	0.00100044846142
ko00950	Isoquinoline alkaloid biosynthesis	6/1061	10/7206	0.00123892420624
ko04210	Apoptosis	12/1061	180/7206	0.00126327309231
ko05164	Influenza A	11/1061	167/7206	0.00179518057935
ko05168	Herpes simplex infection	13/1061	182/7206	0.00204333870688
ko04214	Apoptosis - fly	2/1061	72/7206	0.00208827795579
ko00640	Propanoate metabolism	12/1061	34/7206	0.00232008895862
ko04720	Long-term potentiation	26/1061	99/7206	0.00239965056553
ko05131	Shigellosis	3/1061	82/7206	0.00243475064128
ko04011	MAPK signaling pathway - yeast	1/1061	53/7206	0.00321023562226
ko04270	Vascular smooth muscle contraction	36/1061	154/7206	0.00380539233461
ko04070	Phosphatidylinositol signaling system	28/1061	112/7206	0.00426864630609
ko05161	Hepatitis B	13/1061	173/7206	0.00463309334246
ko05224	Breast cancer	13/1061	174/7206	0.00463956641702
ko04261	Adrenergic signaling in cardiomyocytes	45/1061	205/7206	0.00487971485743
ko04371	Apelin signaling pathway	40/1061	177/7206	0.00491236836709
ko00362	Benzoate degradation	4/1061	6/7206	0.00546900908544
ko01212	Fatty acid metabolism	17/1061	60/7206	0.00547882332224
ko04971	Gastric acid secretion	25/1061	98/7206	0.00569084272359
ko04728	Dopaminergic synapse	41/1061	185/7206	0.00599692500631
ko04721	Synaptic vesicle cycle	21/1061	80/7206	0.0063417324152
ko04723	Retrograde endocannabinoid signaling	39/1061	175/7206	0.0066278149971
ko05169	Epstein-Barr virus infection	17/1061	206/7206	0.00677156412228
ko04711	Circadian rhythm - fly	6/1061	13/7206	0.00681275701079
ko04726	Serotonergic synapse	32/1061	137/7206	0.00691677137699
ko01230	Biosynthesis of amino acids	22/1061	85/7206	0.00787378162122
ko04924	Renin secretion	22/1061	86/7206	0.00831154761614
ko00330	Arginine and proline metabolism	17/1061	61/7206	0.00952627404153
ko04730	Long-term depression	20/1061	78/7206	0.00970550028699
ko04113	Meiosis - yeast	3/1061	70/7206	0.00998487072297
ko05100	Bacterial invasion of epithelial cells	6/1061	99/7206	0.0100293535546
ko02010	ABC transporters	12/1061	39/7206	0.0101600129481
ko04120	Ubiquitin mediated proteolysis	10/1061	138/7206	0.0103805166226
ko04626	Plant-pathogen interaction	7/1061	18/7206	0.0105936399153
ko03420	Nucleotide excision repair	1/1061	46/7206	0.0107316907992
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/1061	4/7206	0.0113340726114
ko00260	Glycine, serine and threonine metabolism	14/1061	48/7206	0.0118581582033
ko00500	Starch and sucrose metabolism	11/1061	35/7206	0.0131475861466
ko04750	Inflammatory mediator regulation of TRP channels	28/1061	122/7206	0.0138173170766
ko05133	Pertussis	5/1061	87/7206	0.0141601054963
ko00220	Arginine biosynthesis	8/1061	24/7206	0.017713071124
ko03050	Proteasome	2/1061	54/7206	0.0188959538131
ko04550	Signaling pathways regulating pluripotency of stem cells	14/1061	165/7206	0.0194276521981
ko04141	Protein processing in endoplasmic reticulum	16/1061	184/7206	0.0198130249329
ko04213	Longevity regulating pathway - multiple species	21/1061	86/7206	0.02015914025
ko05140	Leishmaniasis	4/1061	75/7206	0.020304844594
ko05205	Proteoglycans in cancer	27/1061	271/7206	0.0229057090551
ko04152	AMPK signaling pathway	34/1061	161/7206	0.0243633027364
ko00680	Methane metabolism	10/1061	34/7206	0.0254061480093
ko00410	beta-Alanine metabolism	10/1061	35/7206	0.0294007377461
ko04972	Pancreatic secretion	25/1061	111/7206	0.0294526801781
ko00561	Glycerolipid metabolism	16/1061	63/7206	0.0296202132012
ko05145	Toxoplasmosis	10/1061	126/7206	0.0302518966489
ko04111	Cell cycle - yeast	6/1061	90/7206	0.0343805334976
ko04341	Hedgehog signaling pathway - fly	1/1061	38/7206	0.0354768939459
ko03410	Base excision repair	1/1061	38/7206	0.0354768939459
ko04612	Antigen processing and presentation	5/1061	77/7206	0.0359156135817
ko04215	Apoptosis - multiple species	2/1061	47/7206	0.0384216090553
ko00230	Purine metabolism	39/1061	194/7206	0.0393157851701
ko01522	Endocrine resistance	10/1061	124/7206	0.0395668165392
ko04624	Toll and Imd signaling pathway	2/1061	49/7206	0.0398179629005
ko05200	Pathways in cancer	57/1061	492/7206	0.0410767283584
ko04960	Aldosterone-regulated sodium reabsorption	11/1061	41/7206	0.0426936933578
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/1061	14/7206	0.0434081211389
ko00650	Butanoate metabolism	8/1061	26/7206	0.0445583875901
ko05220	Chronic myeloid leukemia	6/1061	85/7206	0.0446698520793
ko05210	Colorectal cancer	6/1061	86/7206	0.0450485454646
ko00830	Retinol metabolism	11/1061	42/7206	0.0468098069154
ko04014	Ras signaling pathway	53/1061	279/7206	0.0470175033696
ko04115	p53 signaling pathway	5/1061	74/7206	0.0485292005324
ko04350	TGF-beta signaling pathway	8/1061	103/7206	0.0486878455658
ko04520	Adherens junction	8/1061	103/7206	0.0486878455658
ko00710	Carbon fixation in photosynthetic organisms	8/1061	27/7206	0.0492342511427
ko00592	alpha-Linolenic acid metabolism	6/1061	19/7206	0.0494390853415