ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	174/968	423/7206	8.60430927338e-49
ko04724	Glutamatergic synapse	92/968	152/7206	6.46783111611e-43
ko05033	Nicotine addiction	50/968	56/7206	1.21614203851e-37
ko04727	GABAergic synapse	66/968	110/7206	1.25782496822e-30
ko05032	Morphine addiction	66/968	110/7206	1.25782496822e-30
ko04713	Circadian entrainment	74/968	136/7206	2.41641683212e-30
ko04728	Dopaminergic synapse	85/968	185/7206	8.76363248476e-28
ko04723	Retrograde endocannabinoid signaling	77/968	175/7206	9.45306502149e-24
ko04725	Cholinergic synapse	73/968	160/7206	9.72980230596e-24
ko04911	Insulin secretion	59/968	117/7206	3.91743465958e-22
ko04024	cAMP signaling pathway	98/968	279/7206	4.08290040215e-21
ko05031	Amphetamine addiction	46/968	91/7206	1.45523569021e-17
ko04921	Oxytocin signaling pathway	76/968	209/7206	1.52516411701e-17
ko04720	Long-term potentiation	47/968	99/7206	1.58994225165e-16
ko04726	Serotonergic synapse	57/968	137/7206	1.75379230529e-16
ko04261	Adrenergic signaling in cardiomyocytes	73/968	205/7206	2.56985483595e-16
ko04020	Calcium signaling pathway	86/968	265/7206	3.56530190672e-16
ko04721	Synaptic vesicle cycle	39/968	80/7206	2.08891032654e-14
ko04742	Taste transduction	32/968	61/7206	3.48463957525e-13
ko04971	Gastric acid secretion	42/968	98/7206	5.39001300555e-13
ko04970	Salivary secretion	41/968	95/7206	7.72541573577e-13
ko05030	Cocaine addiction	35/968	73/7206	8.65469853317e-13
ko04925	Aldosterone synthesis and secretion	42/968	105/7206	8.60057050226e-12
ko04010	MAPK signaling pathway	84/968	321/7206	4.59275365001e-10
ko04972	Pancreatic secretion	39/968	111/7206	4.24026994623e-09
ko03040	Spliceosome	1/968	145/7206	2.32390390165e-08
ko04022	cGMP-PKG signaling pathway	59/968	216/7206	3.96215172734e-08
ko04072	Phospholipase D signaling pathway	55/968	197/7206	5.4871412591e-08
ko04070	Phosphatidylinositol signaling system	37/968	112/7206	6.86951927756e-08
ko04915	Estrogen signaling pathway	41/968	131/7206	8.06322421945e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	28/968	74/7206	1.09470508092e-07
ko04730	Long-term depression	28/968	78/7206	3.95777791573e-07
ko05168	Herpes simplex infection	5/968	182/7206	8.36757478122e-07
ko04744	Phototransduction	17/968	36/7206	9.17789849451e-07
ko04060	Cytokine-cytokine receptor interaction	6/968	191/7206	1.51970324922e-06
ko04745	Phototransduction - fly	17/968	38/7206	2.35757814362e-06
ko04961	Endocrine and other factor-regulated calcium reabsorption	22/968	59/7206	3.36029402896e-06
ko04540	Gap junction	37/968	128/7206	4.63832822488e-06
ko04360	Axon guidance	56/968	233/7206	8.49028447267e-06
ko04924	Renin secretion	27/968	86/7206	1.5696597759e-05
ko05414	Dilated cardiomyopathy	32/968	112/7206	1.87492746874e-05
ko04912	GnRH signaling pathway	34/968	122/7206	2.09099935596e-05
ko04750	Inflammatory mediator regulation of TRP channels	34/968	122/7206	2.09099935596e-05
ko04260	Cardiac muscle contraction	29/968	98/7206	3.11999359346e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/968	79/7206	3.19166728657e-05
ko05322	Systemic lupus erythematosus	5/968	151/7206	3.28934931708e-05
ko04740	Olfactory transduction	25/968	80/7206	3.63207522455e-05
ko04918	Thyroid hormone synthesis	26/968	86/7206	3.9835015029e-05
ko05203	Viral carcinogenesis	16/968	277/7206	4.48723284386e-05
ko04015	Rap1 signaling pathway	61/968	278/7206	6.9403780174e-05
ko04371	Apelin signaling pathway	42/968	177/7206	0.00018861535332
ko04110	Cell cycle	6/968	145/7206	0.000301521259216
ko04612	Antigen processing and presentation	1/968	77/7206	0.000307532786818
ko04976	Bile secretion	23/968	80/7206	0.000355415877084
ko04350	TGF-beta signaling pathway	3/968	103/7206	0.000412094935957
ko03013	RNA transport	8/968	166/7206	0.000466866596392
ko04514	Cell adhesion molecules (CAMs)	32/968	130/7206	0.000601712959485
ko04141	Protein processing in endoplasmic reticulum	10/968	184/7206	0.000608259387732
ko05034	Alcoholism	51/968	238/7206	0.000644686455177
ko04916	Melanogenesis	34/968	142/7206	0.000662231993144
ko04014	Ras signaling pathway	57/968	279/7206	0.000877299559982
ko04923	Regulation of lipolysis in adipocytes	21/968	77/7206	0.00110679701688
ko03008	Ribosome biogenesis in eukaryotes	2/968	79/7206	0.00145430061791
ko04062	Chemokine signaling pathway	43/968	201/7206	0.00153580981402
ko04270	Vascular smooth muscle contraction	35/968	154/7206	0.00167619469538
ko04640	Hematopoietic cell lineage	1/968	64/7206	0.00246161698584
ko05164	Influenza A	10/968	167/7206	0.00266133318242
ko04114	Oocyte meiosis	31/968	139/7206	0.00359543056232
ko05162	Measles	6/968	120/7206	0.0041746418959
ko00240	Pyrimidine metabolism	5/968	110/7206	0.00427610661862
ko04930	Type II diabetes mellitus	15/968	54/7206	0.00435587535774
ko05321	Inflammatory bowel disease (IBD)	1/968	56/7206	0.00509018517911
ko04120	Ubiquitin mediated proteolysis	8/968	138/7206	0.00529739291029
ko04621	NOD-like receptor signaling pathway	10/968	157/7206	0.00624527508571
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/968	14/7206	0.00664467925295
ko05410	Hypertrophic cardiomyopathy (HCM)	23/968	100/7206	0.00753903363918
ko00562	Inositol phosphate metabolism	21/968	89/7206	0.00754679252044
ko04960	Aldosterone-regulated sodium reabsorption	12/968	41/7206	0.00871804754271
ko04630	Jak-STAT signaling pathway	8/968	132/7206	0.00952768539192
ko04973	Carbohydrate digestion and absorption	12/968	42/7206	0.00977300579698
ko05231	Choline metabolism in cancer	29/968	134/7206	0.00982359987953
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/968	182/7206	0.0108272861496
ko04142	Lysosome	10/968	151/7206	0.0108732304741
ko04964	Proximal tubule bicarbonate reclamation	9/968	29/7206	0.0111379869908
ko04146	Peroxisome	4/968	89/7206	0.0111764047932
ko05214	Glioma	19/968	79/7206	0.0114035752763
ko05169	Epstein-Barr virus infection	16/968	206/7206	0.0127413884021
ko00515	Mannose type O-glycan biosynthesis	8/968	25/7206	0.0135168251415
ko04071	Sphingolipid signaling pathway	33/968	162/7206	0.0137365455491
ko05016	Huntington's disease	17/968	215/7206	0.0144465499162
ko00310	Lysine degradation	3/968	73/7206	0.0147290112755
ko04064	NF-kappa B signaling pathway	5/968	96/7206	0.0149430750722
ko03018	RNA degradation	4/968	84/7206	0.0150254042151
ko04550	Signaling pathways regulating pluripotency of stem cells	12/968	165/7206	0.0152618401281
ko00620	Pyruvate metabolism	1/968	46/7206	0.0165615218439
ko03420	Nucleotide excision repair	1/968	46/7206	0.0165615218439
ko00190	Oxidative phosphorylation	8/968	127/7206	0.017162548486
ko05205	Proteoglycans in cancer	24/968	271/7206	0.0229794701984
ko04213	Longevity regulating pathway - multiple species	19/968	86/7206	0.0248052445207
ko04626	Plant-pathogen interaction	6/968	18/7206	0.0256101086287
ko04217	Necroptosis	14/968	178/7206	0.0256629320123
ko00480	Glutathione metabolism	2/968	55/7206	0.0279070807953
ko04722	Neurotrophin signaling pathway	31/968	160/7206	0.03391760001
ko01200	Carbon metabolism	9/968	128/7206	0.0351530119759
ko04115	p53 signaling pathway	4/968	74/7206	0.0392360745768
ko05140	Leishmaniasis	4/968	75/7206	0.0395029424681
ko05010	Alzheimer's disease	37/968	202/7206	0.046151588057
ko04012	ErbB signaling pathway	22/968	109/7206	0.0463583623461
ko00512	Mucin type O-glycan biosynthesis	8/968	29/7206	0.0481176764427
ko04922	Glucagon signaling pathway	25/968	128/7206	0.0489803252647