ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 21/340 96/7206 2.34191184813e-09 ko04950 Maturity onset diabetes of the young 11/340 29/7206 3.53848448191e-08 ko05217 Basal cell carcinoma 14/340 68/7206 2.51209631943e-06 ko04550 Signaling pathways regulating pluripotency of stem cells 22/340 165/7206 8.71779971207e-06 ko04260 Cardiac muscle contraction 16/340 98/7206 1.17066287742e-05 ko05410 Hypertrophic cardiomyopathy (HCM) 16/340 100/7206 1.52495344645e-05 ko05224 Breast cancer 22/340 174/7206 2.05429234128e-05 ko04340 Hedgehog signaling pathway 11/340 58/7206 6.78556462218e-05 ko04512 ECM-receptor interaction 13/340 79/7206 7.13625379726e-05 ko05414 Dilated cardiomyopathy 15/340 112/7206 0.000226897475951 ko05203 Viral carcinogenesis 2/340 277/7206 0.000238985351139 ko05200 Pathways in cancer 41/340 492/7206 0.000357621665517 ko04360 Axon guidance 24/340 233/7206 0.000379569733964 ko04510 Focal adhesion 23/340 240/7206 0.00100268582902 ko05205 Proteoglycans in cancer 25/340 271/7206 0.00112877861798 ko05202 Transcriptional misregulation in cancer 19/340 188/7206 0.0014380354075 ko05218 Melanoma 11/340 85/7206 0.00203605957255 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/340 79/7206 0.00378599712181 ko04261 Adrenergic signaling in cardiomyocytes 19/340 205/7206 0.00410670828346 ko04151 PI3K-Akt signaling pathway 31/340 390/7206 0.00430720822616 ko03013 RNA transport 1/340 166/7206 0.0048602219181 ko04062 Chemokine signaling pathway 2/340 201/7206 0.00622455726172 ko04611 Platelet activation 1/340 163/7206 0.00740772814443 ko04341 Hedgehog signaling pathway - fly 6/340 38/7206 0.00810541059868 ko04330 Notch signaling pathway 8/340 62/7206 0.00824381499439 ko00230 Purine metabolism 2/340 194/7206 0.00892300118876 ko04072 Phospholipase D signaling pathway 2/340 197/7206 0.00920763561376 ko04612 Antigen processing and presentation 9/340 77/7206 0.00990071779174 ko04724 Glutamatergic synapse 1/340 152/7206 0.0104130497563 ko04978 Mineral absorption 6/340 40/7206 0.0104153192618 ko04964 Proximal tubule bicarbonate reclamation 5/340 29/7206 0.0105825287672 ko05012 Parkinson's disease 1/340 155/7206 0.0108118688774 ko04976 Bile secretion 9/340 80/7206 0.0125858446827 ko04114 Oocyte meiosis 1/340 139/7206 0.0148258116443 ko00350 Tyrosine metabolism 5/340 33/7206 0.0181421977099 ko05034 Alcoholism 4/340 238/7206 0.019029549438 ko05216 Thyroid cancer 5/340 34/7206 0.0204727151577 ko04120 Ubiquitin mediated proteolysis 1/340 138/7206 0.0225518266915 ko05164 Influenza A 2/340 167/7206 0.0249178009033 ko00430 Taurine and hypotaurine metabolism 3/340 14/7206 0.0257167062763 ko04666 Fc gamma R-mediated phagocytosis 1/340 122/7206 0.0308722221575 ko04310 Wnt signaling pathway 15/340 181/7206 0.0310618111697 ko05142 Chagas disease (American trypanosomiasis) 1/340 130/7206 0.032716588956 ko04621 NOD-like receptor signaling pathway 2/340 157/7206 0.0347595049452 ko04144 Endocytosis 8/340 342/7206 0.0352018965285 ko04722 Neurotrophin signaling pathway 2/340 160/7206 0.0353334314693 ko04060 Cytokine-cytokine receptor interaction 3/340 191/7206 0.0359755614874 ko05162 Measles 1/340 120/7206 0.0460709205 ko04217 Necroptosis 3/340 178/7206 0.0487788372295 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/340 182/7206 0.0492016681212 ko05322 Systemic lupus erythematosus 2/340 151/7206 0.0492536080008