ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/904	423/7206	2.76636616746e-30
ko05033	Nicotine addiction	41/904	56/7206	1.20982139427e-25
ko04724	Glutamatergic synapse	66/904	152/7206	9.10865159443e-22
ko05032	Morphine addiction	52/904	110/7206	2.16962879407e-19
ko04727	GABAergic synapse	51/904	110/7206	1.40905003612e-18
ko04728	Dopaminergic synapse	65/904	185/7206	8.43011987004e-16
ko04024	cAMP signaling pathway	80/904	279/7206	1.91201491998e-13
ko04713	Circadian entrainment	50/904	136/7206	2.69487600392e-13
ko04725	Cholinergic synapse	55/904	160/7206	4.29022269896e-13
ko04723	Retrograde endocannabinoid signaling	58/904	175/7206	5.75582586542e-13
ko04360	Axon guidance	68/904	233/7206	5.5798596289e-12
ko04721	Synaptic vesicle cycle	33/904	80/7206	9.29473214746e-11
ko05030	Cocaine addiction	29/904	73/7206	3.69835234226e-09
ko04911	Insulin secretion	38/904	117/7206	1.17066301911e-08
ko04010	MAPK signaling pathway	74/904	321/7206	9.47111012044e-08
ko04742	Taste transduction	24/904	61/7206	1.03194507583e-07
ko04726	Serotonergic synapse	40/904	137/7206	1.43551401063e-07
ko04261	Adrenergic signaling in cardiomyocytes	53/904	205/7206	1.46288111333e-07
ko03040	Spliceosome	1/904	145/7206	1.49242969385e-07
ko04020	Calcium signaling pathway	62/904	265/7206	6.1782195367e-07
ko04921	Oxytocin signaling pathway	51/904	209/7206	1.97957427914e-06
ko05031	Amphetamine addiction	28/904	91/7206	3.33257534801e-06
ko05203	Viral carcinogenesis	13/904	277/7206	1.11616872244e-05
ko03013	RNA transport	5/904	166/7206	2.47975043081e-05
ko05322	Systemic lupus erythematosus	4/904	151/7206	2.94279096732e-05
ko04744	Phototransduction	14/904	36/7206	5.67132963532e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/904	74/7206	6.64982192515e-05
ko01200	Carbon metabolism	3/904	128/7206	6.86560142286e-05
ko04514	Cell adhesion molecules (CAMs)	33/904	130/7206	7.33608884581e-05
ko05168	Herpes simplex infection	7/904	182/7206	9.17701191131e-05
ko00240	Pyrimidine metabolism	2/904	110/7206	0.000110031320176
ko04970	Salivary secretion	26/904	95/7206	0.000111844518561
ko04014	Ras signaling pathway	57/904	279/7206	0.000140520996322
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/904	79/7206	0.000216805906138
ko04972	Pancreatic secretion	28/904	111/7206	0.000226162797649
ko05164	Influenza A	7/904	167/7206	0.000336972560015
ko03018	RNA degradation	1/904	84/7206	0.000342326939103
ko03008	Ribosome biogenesis in eukaryotes	1/904	79/7206	0.000488342119014
ko04120	Ubiquitin mediated proteolysis	5/904	138/7206	0.000606595375784
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/904	14/7206	0.000736521879419
ko04621	NOD-like receptor signaling pathway	7/904	157/7206	0.000890251332307
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/904	59/7206	0.0010123862609
ko04214	Apoptosis - fly	1/904	72/7206	0.00108642814409
ko00010	Glycolysis / Gluconeogenesis	1/904	74/7206	0.00111857146214
ko04730	Long-term depression	20/904	78/7206	0.00151132201974
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/904	182/7206	0.00207660742835
ko04141	Protein processing in endoplasmic reticulum	10/904	184/7206	0.00211995468007
ko04540	Gap junction	28/904	128/7206	0.00275088991142
ko04217	Necroptosis	10/904	178/7206	0.00277206348118
ko04971	Gastric acid secretion	23/904	98/7206	0.00295441275177
ko04720	Long-term potentiation	23/904	99/7206	0.00313812926687
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	9/904	26/7206	0.00315545478095
ko05414	Dilated cardiomyopathy	25/904	112/7206	0.00357068126272
ko04391	Hippo signaling pathway - fly	21/904	90/7206	0.00369890787513
ko04015	Rap1 signaling pathway	51/904	278/7206	0.00414067025174
ko00190	Oxidative phosphorylation	6/904	127/7206	0.00430375159994
ko04612	Antigen processing and presentation	2/904	77/7206	0.00479354039599
ko04260	Cardiac muscle contraction	22/904	98/7206	0.00529271395408
ko05133	Pertussis	3/904	87/7206	0.00537827566975
ko04060	Cytokine-cytokine receptor interaction	12/904	191/7206	0.00553107625303
ko04022	cGMP-PKG signaling pathway	41/904	216/7206	0.00634447044542
ko04925	Aldosterone synthesis and secretion	23/904	105/7206	0.00681656403524
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/904	15/7206	0.00702590296907
ko01230	Biosynthesis of amino acids	3/904	85/7206	0.00765187758176
ko04976	Bile secretion	18/904	80/7206	0.0106177179418
ko00280	Valine, leucine and isoleucine degradation	1/904	54/7206	0.0117135945863
ko00480	Glutathione metabolism	1/904	55/7206	0.0120856790668
ko04915	Estrogen signaling pathway	26/904	131/7206	0.0158494555282
ko04110	Cell cycle	9/904	145/7206	0.0159655146051
ko00590	Arachidonic acid metabolism	1/904	52/7206	0.0180079006582
ko05152	Tuberculosis	13/904	187/7206	0.0182439461732
ko05169	Epstein-Barr virus infection	15/904	206/7206	0.0185575099089
ko04640	Hematopoietic cell lineage	2/904	64/7206	0.0206912252644
ko04072	Phospholipase D signaling pathway	36/904	197/7206	0.0212490334403
ko05140	Leishmaniasis	3/904	75/7206	0.0213828415744
ko04964	Proximal tubule bicarbonate reclamation	8/904	29/7206	0.0227987947377
ko05205	Proteoglycans in cancer	22/904	271/7206	0.0244734313651
ko04142	Lysosome	10/904	151/7206	0.0247967664778
ko05131	Shigellosis	4/904	82/7206	0.029388316595
ko05410	Hypertrophic cardiomyopathy (HCM)	20/904	100/7206	0.0319251388706
ko05012	Parkinson's disease	11/904	155/7206	0.0368366195904
ko03022	Basal transcription factors	1/904	44/7206	0.037264543594
ko04218	Cellular senescence	13/904	177/7206	0.0376611673924
ko04930	Type II diabetes mellitus	12/904	54/7206	0.03872299025
ko05321	Inflammatory bowel disease (IBD)	2/904	56/7206	0.0409743291238
ko04670	Leukocyte transendothelial migration	11/904	151/7206	0.0469579364317
ko05210	Colorectal cancer	17/904	86/7206	0.0488532957703
ko04924	Renin secretion	17/904	86/7206	0.0488532957703