ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	32/618	56/7206	2.08464069301e-20
ko04724	Glutamatergic synapse	48/618	152/7206	2.37713865497e-16
ko05032	Morphine addiction	40/618	110/7206	3.39410612676e-16
ko04727	GABAergic synapse	39/618	110/7206	2.16839884077e-15
ko04080	Neuroactive ligand-receptor interaction	87/618	423/7206	2.28692777635e-15
ko04723	Retrograde endocannabinoid signaling	47/618	175/7206	4.51206527582e-13
ko04744	Phototransduction	20/618	36/7206	6.80359119121e-13
ko04024	cAMP signaling pathway	60/618	279/7206	9.19443333187e-12
ko04728	Dopaminergic synapse	43/618	185/7206	7.43157004786e-10
ko04721	Synaptic vesicle cycle	26/618	80/7206	9.98370287389e-10
ko04713	Circadian entrainment	35/618	136/7206	1.68837896472e-09
ko04725	Cholinergic synapse	37/618	160/7206	1.36894856223e-08
ko04911	Insulin secretion	30/618	117/7206	2.75529764622e-08
ko05030	Cocaine addiction	20/618	73/7206	1.9047422976e-06
ko04010	MAPK signaling pathway	53/618	321/7206	3.01750790033e-06
ko04921	Oxytocin signaling pathway	39/618	209/7206	3.46975210274e-06
ko04261	Adrenergic signaling in cardiomyocytes	38/618	205/7206	5.28983030177e-06
ko04020	Calcium signaling pathway	45/618	265/7206	8.78572429808e-06
ko04726	Serotonergic synapse	28/618	137/7206	1.4720875437e-05
ko04970	Salivary secretion	21/618	95/7206	3.99585997164e-05
ko05031	Amphetamine addiction	20/618	91/7206	6.6261244851e-05
ko04360	Axon guidance	37/618	233/7206	0.0001947263647
ko05322	Systemic lupus erythematosus	2/618	151/7206	0.00030963995473
ko05164	Influenza A	3/618	167/7206	0.000386479933085
ko05014	Amyotrophic lateral sclerosis (ALS)	16/618	74/7206	0.000425591164467
ko04964	Proximal tubule bicarbonate reclamation	9/618	29/7206	0.000494642971969
ko04070	Phosphatidylinositol signaling system	21/618	112/7206	0.000505252042671
ko05203	Viral carcinogenesis	9/618	277/7206	0.000602746231582
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/618	14/7206	0.000640210126869
ko05205	Proteoglycans in cancer	9/618	271/7206	0.000802324154279
ko04072	Phospholipase D signaling pathway	31/618	197/7206	0.00105853720846
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/618	59/7206	0.00120080317504
ko04972	Pancreatic secretion	20/618	111/7206	0.00157243805379
ko03013	RNA transport	4/618	166/7206	0.0017999982092
ko04720	Long-term potentiation	18/618	99/7206	0.00180328318278
ko05168	Herpes simplex infection	5/618	182/7206	0.00192600728966
ko04120	Ubiquitin mediated proteolysis	3/618	138/7206	0.00318268364953
ko04976	Bile secretion	15/618	80/7206	0.00364634635961
ko04144	Endocytosis	45/618	342/7206	0.00386306262279
ko04925	Aldosterone synthesis and secretion	18/618	105/7206	0.00411715213435
ko04014	Ras signaling pathway	38/618	279/7206	0.00425622354106
ko04742	Taste transduction	12/618	61/7206	0.00496285017761
ko04260	Cardiac muscle contraction	17/618	98/7206	0.00519772512323
ko04141	Protein processing in endoplasmic reticulum	6/618	184/7206	0.006994517209
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/618	79/7206	0.00748144413533
ko04022	cGMP-PKG signaling pathway	30/618	216/7206	0.00890120117719
ko03018	RNA degradation	1/618	84/7206	0.0093146075588
ko05218	Melanoma	1/618	85/7206	0.00953224361231
ko04145	Phagosome	5/618	162/7206	0.00970641715939
ko04971	Gastric acid secretion	16/618	98/7206	0.0102000651494
ko05169	Epstein-Barr virus infection	8/618	206/7206	0.0111750737744
ko04060	Cytokine-cytokine receptor interaction	7/618	191/7206	0.0120358588437
ko04612	Antigen processing and presentation	1/618	77/7206	0.0133065932685
ko04610	Complement and coagulation cascades	1/618	79/7206	0.0135232886641
ko05414	Dilated cardiomyopathy	17/618	112/7206	0.0169507765732
ko04142	Lysosome	5/618	151/7206	0.0175620524316
ko04960	Aldosterone-regulated sodium reabsorption	8/618	41/7206	0.0211702270396
ko00190	Oxidative phosphorylation	4/618	127/7206	0.0240539816261
ko00240	Pyrimidine metabolism	3/618	110/7206	0.0241186794469
ko04514	Cell adhesion molecules (CAMs)	19/618	130/7206	0.0249815136668
ko04710	Circadian rhythm	8/618	43/7206	0.0276440770496
ko04071	Sphingolipid signaling pathway	22/618	162/7206	0.0316473506886
ko04810	Regulation of actin cytoskeleton	13/618	264/7206	0.0324670864385
ko02024	Quorum sensing	4/618	15/7206	0.0340695621827
ko04540	Gap junction	18/618	128/7206	0.036322593713
ko04923	Regulation of lipolysis in adipocytes	12/618	77/7206	0.03796933152
ko04730	Long-term depression	12/618	78/7206	0.0401602252017
ko04640	Hematopoietic cell lineage	1/618	64/7206	0.0411633094167
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/618	182/7206	0.0430963932254
ko05131	Shigellosis	2/618	82/7206	0.0452293872569
ko04918	Thyroid hormone synthesis	13/618	86/7206	0.0486373745849