ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 33/236 191/7206 1.40248450106e-15 ko05340 Primary immunodeficiency 14/236 30/7206 1.01694114766e-13 ko04650 Natural killer cell mediated cytotoxicity 21/236 97/7206 2.9818995428e-12 ko04659 Th17 cell differentiation 19/236 106/7206 1.05799132226e-09 ko05152 Tuberculosis 25/236 187/7206 1.48569546327e-09 ko05330 Allograft rejection 10/236 24/7206 1.53993232312e-09 ko05140 Leishmaniasis 16/236 75/7206 1.61308137015e-09 ko04612 Antigen processing and presentation 16/236 77/7206 2.43260881929e-09 ko05145 Toxoplasmosis 20/236 126/7206 3.50421630434e-09 ko05164 Influenza A 23/236 167/7206 3.90438241933e-09 ko05162 Measles 19/236 120/7206 9.16937021933e-09 ko04380 Osteoclast differentiation 20/236 134/7206 1.05019268967e-08 ko05320 Autoimmune thyroid disease 10/236 29/7206 1.36106056593e-08 ko05321 Inflammatory bowel disease (IBD) 13/236 56/7206 1.93955470018e-08 ko05332 Graft-versus-host disease 8/236 18/7206 3.8771224002e-08 ko05168 Herpes simplex infection 22/236 182/7206 9.69832736708e-08 ko04640 Hematopoietic cell lineage 13/236 64/7206 1.0676843907e-07 ko04145 Phagosome 19/236 162/7206 1.20631492826e-06 ko05150 Staphylococcus aureus infection 9/236 36/7206 1.61805040895e-06 ko04672 Intestinal immune network for IgA production 9/236 37/7206 2.0777527119e-06 ko04062 Chemokine signaling pathway 21/236 201/7206 2.21287727605e-06 ko04658 Th1 and Th2 cell differentiation 14/236 96/7206 2.43443776749e-06 ko04620 Toll-like receptor signaling pathway 14/236 100/7206 4.00022968099e-06 ko04940 Type I diabetes mellitus 8/236 32/7206 6.25873409995e-06 ko05310 Asthma 6/236 17/7206 1.05842731542e-05 ko04064 NF-kappa B signaling pathway 13/236 96/7206 1.29187258366e-05 ko05133 Pertussis 12/236 87/7206 2.31459496125e-05 ko04660 T cell receptor signaling pathway 14/236 124/7206 4.892792189e-05 ko03050 Proteasome 9/236 54/7206 5.46285783045e-05 ko05144 Malaria 8/236 45/7206 8.87483206601e-05 ko04630 Jak-STAT signaling pathway 14/236 132/7206 9.75747484198e-05 ko04621 NOD-like receptor signaling pathway 15/236 157/7206 0.000180980955495 ko05416 Viral myocarditis 8/236 55/7206 0.000378024556216 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/236 191/7206 0.00049973884588 ko04662 B cell receptor signaling pathway 10/236 88/7206 0.000562307549313 ko04666 Fc gamma R-mediated phagocytosis 12/236 122/7206 0.000615472407802 ko05323 Rheumatoid arthritis 10/236 89/7206 0.0006156364877 ko04217 Necroptosis 15/236 178/7206 0.00070188763589 ko04610 Complement and coagulation cascades 9/236 79/7206 0.00103841415896 ko04514 Cell adhesion molecules (CAMs) 12/236 130/7206 0.00108500947594 ko05161 Hepatitis B 14/236 173/7206 0.00155701537327 ko05142 Chagas disease (American trypanosomiasis) 11/236 130/7206 0.00345905456176 ko04664 Fc epsilon RI signaling pathway 8/236 77/7206 0.00352351143412 ko00120 Primary bile acid biosynthesis 4/236 20/7206 0.00359264927033 ko04622 RIG-I-like receptor signaling pathway 7/236 62/7206 0.00392010176986 ko05132 Salmonella infection 9/236 98/7206 0.00464155731399 ko00590 Arachidonic acid metabolism 6/236 52/7206 0.00668438927253 ko04360 Axon guidance 1/236 233/7206 0.00742279360896 ko04611 Platelet activation 12/236 163/7206 0.0112012500048 ko05146 Amoebiasis 8/236 99/7206 0.0155469217543 ko00592 alpha-Linolenic acid metabolism 3/236 19/7206 0.0228046320033 ko04144 Endocytosis 19/236 342/7206 0.0272352636249 ko05206 MicroRNAs in cancer 1/236 177/7206 0.0314720481526 ko04310 Wnt signaling pathway 1/236 181/7206 0.0317834310477 ko04670 Leukocyte transendothelial migration 10/236 151/7206 0.0323804989071 ko05160 Hepatitis C 10/236 153/7206 0.0341396022127 ko04072 Phospholipase D signaling pathway 12/236 197/7206 0.0381942894937 ko05166 HTLV-I infection 16/236 292/7206 0.0416589402025 ko05224 Breast cancer 1/236 174/7206 0.0473373851218 ko05016 Huntington's disease 2/236 215/7206 0.0493860287126