ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	126/659	423/7206	2.09608059488e-36
ko05033	Nicotine addiction	39/659	56/7206	2.36211612118e-28
ko04724	Glutamatergic synapse	59/659	152/7206	1.16200273605e-23
ko05032	Morphine addiction	44/659	110/7206	1.70311559089e-18
ko04721	Synaptic vesicle cycle	36/659	80/7206	2.43991497202e-17
ko04728	Dopaminergic synapse	56/659	185/7206	1.15304814367e-16
ko04727	GABAergic synapse	41/659	110/7206	5.08921687868e-16
ko04024	cAMP signaling pathway	68/659	279/7206	1.19672435555e-14
ko04723	Retrograde endocannabinoid signaling	51/659	175/7206	1.59160300093e-14
ko04713	Circadian entrainment	41/659	136/7206	1.94521964325e-12
ko04725	Cholinergic synapse	44/659	160/7206	9.77599861832e-12
ko04911	Insulin secretion	33/659	117/7206	2.00659716114e-09
ko05030	Cocaine addiction	25/659	73/7206	2.31743889327e-09
ko04726	Serotonergic synapse	35/659	137/7206	1.13642145818e-08
ko04742	Taste transduction	21/659	61/7206	4.04831423248e-08
ko04261	Adrenergic signaling in cardiomyocytes	44/659	205/7206	4.88375614812e-08
ko04020	Calcium signaling pathway	52/659	265/7206	8.68182974585e-08
ko05031	Amphetamine addiction	25/659	91/7206	3.24837487323e-07
ko04514	Cell adhesion molecules (CAMs)	31/659	130/7206	4.21999545319e-07
ko05203	Viral carcinogenesis	5/659	277/7206	6.20607016241e-07
ko04921	Oxytocin signaling pathway	42/659	209/7206	1.01398015164e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/659	74/7206	1.60103111311e-06
ko04010	MAPK signaling pathway	55/659	321/7206	3.71490252419e-06
ko04060	Cytokine-cytokine receptor interaction	3/659	191/7206	2.00731009562e-05
ko03040	Spliceosome	1/659	145/7206	2.68966837684e-05
ko04970	Salivary secretion	22/659	95/7206	3.29625890553e-05
ko04360	Axon guidance	41/659	233/7206	3.85790261713e-05
ko04720	Long-term potentiation	22/659	99/7206	6.45143046304e-05
ko05164	Influenza A	3/659	167/7206	0.000185356796448
ko04120	Ubiquitin mediated proteolysis	2/659	138/7206	0.000285374332552
ko04972	Pancreatic secretion	22/659	111/7206	0.000395863285508
ko05322	Systemic lupus erythematosus	3/659	151/7206	0.00053481065712
ko05169	Epstein-Barr virus infection	6/659	206/7206	0.000539509615676
ko04730	Long-term depression	17/659	78/7206	0.000545895484473
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/659	79/7206	0.000637828683868
ko05205	Proteoglycans in cancer	10/659	271/7206	0.000768965431996
ko04350	TGF-beta signaling pathway	1/659	103/7206	0.000886906873021
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/659	14/7206	0.00090419653066
ko05168	Herpes simplex infection	5/659	182/7206	0.000981014600565
ko04110	Cell cycle	3/659	145/7206	0.00111792983266
ko04260	Cardiac muscle contraction	19/659	98/7206	0.00129215004054
ko04621	NOD-like receptor signaling pathway	4/659	157/7206	0.00178150052409
ko04915	Estrogen signaling pathway	23/659	131/7206	0.00193737591506
ko04540	Gap junction	22/659	128/7206	0.00308050112813
ko04964	Proximal tubule bicarbonate reclamation	8/659	29/7206	0.00354480760569
ko04022	cGMP-PKG signaling pathway	33/659	216/7206	0.00365036045301
ko03013	RNA transport	5/659	166/7206	0.00373241764579
ko04971	Gastric acid secretion	18/659	98/7206	0.00387951352504
ko04744	Phototransduction	9/659	36/7206	0.00417456456212
ko04072	Phospholipase D signaling pathway	30/659	197/7206	0.00534044010858
ko05162	Measles	3/659	120/7206	0.00617110264266
ko03018	RNA degradation	1/659	84/7206	0.006356145776
ko05166	HTLV-I infection	14/659	292/7206	0.00673810956634
ko04966	Collecting duct acid secretion	7/659	26/7206	0.00726569281739
ko05414	Dilated cardiomyopathy	19/659	112/7206	0.00738425366895
ko04014	Ras signaling pathway	39/659	279/7206	0.00765680677455
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/659	182/7206	0.00874241440627
ko04141	Protein processing in endoplasmic reticulum	7/659	184/7206	0.00889252243461
ko04925	Aldosterone synthesis and secretion	18/659	105/7206	0.00913810045321
ko03008	Ribosome biogenesis in eukaryotes	1/659	79/7206	0.00916523232391
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/659	59/7206	0.00966609383283
ko00240	Pyrimidine metabolism	3/659	110/7206	0.012133667396
ko01200	Carbon metabolism	4/659	128/7206	0.0125846934647
ko04924	Renin secretion	15/659	86/7206	0.0129421008328
ko04214	Apoptosis - fly	1/659	72/7206	0.0130633292339
ko00310	Lysine degradation	1/659	73/7206	0.0130931043924
ko04930	Type II diabetes mellitus	11/659	54/7206	0.0141101971599
ko04146	Peroxisome	2/659	89/7206	0.015675663149
ko04071	Sphingolipid signaling pathway	24/659	162/7206	0.0179769813528
ko04640	Hematopoietic cell lineage	1/659	64/7206	0.0278194939921
ko05161	Hepatitis B	8/659	173/7206	0.0326160512604
ko04015	Rap1 signaling pathway	36/659	278/7206	0.0329769221844
ko00564	Glycerophospholipid metabolism	3/659	99/7206	0.0330564505135
ko05146	Amoebiasis	3/659	99/7206	0.0330564505135
ko05202	Transcriptional misregulation in cancer	9/659	188/7206	0.0389130736467
ko05140	Leishmaniasis	2/659	75/7206	0.044422782269
ko04612	Antigen processing and presentation	2/659	77/7206	0.0446814945172
ko04064	NF-kappa B signaling pathway	3/659	96/7206	0.0467765562