ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 16/113 120/7206 3.64588929453e-11 ko04380 Osteoclast differentiation 16/113 134/7206 1.99351768483e-10 ko05164 Influenza A 16/113 167/7206 5.33193612092e-09 ko04621 NOD-like receptor signaling pathway 15/113 157/7206 1.73766256591e-08 ko04660 T cell receptor signaling pathway 12/113 124/7206 4.48597589581e-07 ko04623 Cytosolic DNA-sensing pathway 7/113 41/7206 2.80088519672e-06 ko05168 Herpes simplex infection 13/113 182/7206 4.69038530726e-06 ko04060 Cytokine-cytokine receptor interaction 13/113 191/7206 7.97376864447e-06 ko05161 Hepatitis B 12/113 173/7206 1.50469319639e-05 ko05162 Measles 10/113 120/7206 1.64924304261e-05 ko04064 NF-kappa B signaling pathway 9/113 96/7206 1.72659956091e-05 ko04210 Apoptosis 12/113 180/7206 2.24392682645e-05 ko04620 Toll-like receptor signaling pathway 9/113 100/7206 2.40420925023e-05 ko05160 Hepatitis C 11/113 153/7206 2.49324216987e-05 ko05142 Chagas disease (American trypanosomiasis) 10/113 130/7206 3.32058173772e-05 ko05131 Shigellosis 8/113 82/7206 3.87232536862e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/113 191/7206 4.04582746815e-05 ko04672 Intestinal immune network for IgA production 5/113 37/7206 0.000253430453318 ko04622 RIG-I-like receptor signaling pathway 6/113 62/7206 0.000391660146951 ko05323 Rheumatoid arthritis 7/113 89/7206 0.000462353104815 ko05120 Epithelial cell signaling in Helicobacter pylori infection 7/113 92/7206 0.000565624784163 ko04658 Th1 and Th2 cell differentiation 7/113 96/7206 0.000731027392223 ko05145 Toxoplasmosis 8/113 126/7206 0.000771013945384 ko05132 Salmonella infection 7/113 98/7206 0.000826984415534 ko04624 Toll and Imd signaling pathway 5/113 49/7206 0.000954787142049 ko04630 Jak-STAT signaling pathway 8/113 132/7206 0.00104598546467 ko05140 Leishmaniasis 6/113 75/7206 0.0010878998882 ko05220 Chronic myeloid leukemia 6/113 85/7206 0.00208212480411 ko04932 Non-alcoholic fatty liver disease (NAFLD) 9/113 182/7206 0.00214334577804 ko04657 IL-17 signaling pathway 6/113 87/7206 0.0023440954286 ko05133 Pertussis 6/113 87/7206 0.0023440954286 ko04662 B cell receptor signaling pathway 6/113 88/7206 0.00248404153518 ko05134 Legionellosis 5/113 74/7206 0.00591849470769 ko04659 Th17 cell differentiation 6/113 106/7206 0.00623232500377 ko04217 Necroptosis 8/113 178/7206 0.00668478792276 ko05321 Inflammatory bowel disease (IBD) 4/113 56/7206 0.0112587100428 ko04917 Prolactin signaling pathway 5/113 87/7206 0.0115688762873 ko04920 Adipocytokine signaling pathway 5/113 89/7206 0.0126807964298 ko04062 Chemokine signaling pathway 8/113 201/7206 0.0133963607241 ko04611 Platelet activation 7/113 163/7206 0.0138767419948 ko04080 Neuroactive ligand-receptor interaction 1/113 423/7206 0.0144323175941 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/113 135/7206 0.0190825414654 ko05100 Bacterial invasion of epithelial cells 5/113 99/7206 0.0193321615761 ko04931 Insulin resistance 6/113 137/7206 0.0203630468898 ko04218 Cellular senescence 7/113 177/7206 0.0209058148372 ko05166 HTLV-I infection 10/113 292/7206 0.024962370695 ko05152 Tuberculosis 7/113 187/7206 0.027243605625 ko00051 Fructose and mannose metabolism 3/113 42/7206 0.0276772457336 ko04612 Antigen processing and presentation 4/113 77/7206 0.0323493107202 ko04010 MAPK signaling pathway 10/113 321/7206 0.0342383426626 ko04215 Apoptosis - multiple species 3/113 47/7206 0.0369671104239 ko04137 Mitophagy - animal 4/113 82/7206 0.0394226397837 ko04921 Oxytocin signaling pathway 7/113 209/7206 0.0455301056545 ko05210 Colorectal cancer 4/113 86/7206 0.0456693395373 ko04068 FoxO signaling pathway 6/113 167/7206 0.0469628696929