ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	53/483	152/7206	2.9858754938e-25
ko05033	Nicotine addiction	33/483	56/7206	4.84227786935e-25
ko04080	Neuroactive ligand-receptor interaction	87/483	423/7206	1.306662134e-22
ko04721	Synaptic vesicle cycle	32/483	80/7206	1.0995294593e-17
ko04713	Circadian entrainment	39/483	136/7206	1.65203740582e-15
ko04728	Dopaminergic synapse	46/483	185/7206	1.79722168109e-15
ko04723	Retrograde endocannabinoid signaling	44/483	175/7206	4.93411470909e-15
ko04727	GABAergic synapse	34/483	110/7206	9.7306309706e-15
ko05032	Morphine addiction	34/483	110/7206	9.7306309706e-15
ko04024	cAMP signaling pathway	50/483	279/7206	7.11923913865e-11
ko04911	Insulin secretion	30/483	117/7206	7.54967527412e-11
ko04725	Cholinergic synapse	35/483	160/7206	2.35805691821e-10
ko05014	Amyotrophic lateral sclerosis (ALS)	22/483	74/7206	1.29527677278e-09
ko05031	Amphetamine addiction	24/483	91/7206	3.36825374033e-09
ko04720	Long-term potentiation	24/483	99/7206	2.05910836524e-08
ko04261	Adrenergic signaling in cardiomyocytes	36/483	205/7206	6.48980194174e-08
ko04726	Serotonergic synapse	28/483	137/7206	7.43250989096e-08
ko04514	Cell adhesion molecules (CAMs)	27/483	130/7206	8.99030742708e-08
ko05030	Cocaine addiction	18/483	73/7206	9.44499802521e-07
ko04970	Salivary secretion	20/483	95/7206	3.44568795949e-06
ko04020	Calcium signaling pathway	38/483	265/7206	7.01910840165e-06
ko04742	Taste transduction	15/483	61/7206	7.94399564814e-06
ko04921	Oxytocin signaling pathway	32/483	209/7206	8.19546441241e-06
ko04730	Long-term depression	16/483	78/7206	4.5948425028e-05
ko04060	Cytokine-cytokine receptor interaction	1/483	191/7206	4.66426054638e-05
ko04010	MAPK signaling pathway	41/483	321/7206	5.05628143602e-05
ko04972	Pancreatic secretion	19/483	111/7206	0.000125594012292
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/483	14/7206	0.000166024652084
ko04966	Collecting duct acid secretion	8/483	26/7206	0.000204414281711
ko04550	Signaling pathways regulating pluripotency of stem cells	1/483	165/7206	0.000214507891642
ko05164	Influenza A	1/483	167/7206	0.000219792638704
ko04971	Gastric acid secretion	16/483	98/7206	0.000728298673344
ko04022	cGMP-PKG signaling pathway	28/483	216/7206	0.000734415767255
ko05203	Viral carcinogenesis	6/483	277/7206	0.000824012200591
ko03040	Spliceosome	1/483	145/7206	0.00106485977583
ko04140	Autophagy - animal	2/483	164/7206	0.00140329638612
ko04120	Ubiquitin mediated proteolysis	1/483	138/7206	0.00152088687985
ko00512	Mucin type O-glycan biosynthesis	7/483	29/7206	0.0024872185397
ko04360	Axon guidance	28/483	233/7206	0.00297130400398
ko05322	Systemic lupus erythematosus	2/483	151/7206	0.00434125252148
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/483	59/7206	0.00533855331562
ko05215	Prostate cancer	1/483	111/7206	0.006672694466
ko04068	FoxO signaling pathway	3/483	167/7206	0.0068804718308
ko04915	Estrogen signaling pathway	17/483	131/7206	0.00740010690822
ko05110	Vibrio cholerae infection	10/483	63/7206	0.0085477119862
ko05205	Proteoglycans in cancer	8/483	271/7206	0.00885586582504
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/483	92/7206	0.0095873352374
ko05168	Herpes simplex infection	4/483	182/7206	0.00988822456576
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/483	182/7206	0.00988822456576
ko04150	mTOR signaling pathway	4/483	184/7206	0.0100912642569
ko05010	Alzheimer's disease	23/483	202/7206	0.0140500669647
ko04924	Renin secretion	12/483	86/7206	0.0141251798849
ko04014	Ras signaling pathway	29/483	279/7206	0.0193463562715
ko04260	Cardiac muscle contraction	13/483	98/7206	0.0219687845116
ko05166	HTLV-I infection	10/483	292/7206	0.0222712949349
ko05169	Epstein-Barr virus infection	6/483	206/7206	0.0231140007032
ko05034	Alcoholism	25/483	238/7206	0.0240137440316
ko04626	Plant-pathogen interaction	4/483	18/7206	0.0287382636709
ko04072	Phospholipase D signaling pathway	21/483	197/7206	0.0298936683461
ko04146	Peroxisome	1/483	89/7206	0.0300614978661
ko04744	Phototransduction	6/483	36/7206	0.0307105718357
ko00240	Pyrimidine metabolism	2/483	110/7206	0.0334171728713
ko04621	NOD-like receptor signaling pathway	4/483	157/7206	0.0342587739539
ko04630	Jak-STAT signaling pathway	3/483	132/7206	0.0344540513794
ko04510	Focal adhesion	8/483	240/7206	0.0344637615655
ko04931	Insulin resistance	3/483	137/7206	0.0357599481632
ko04145	Phagosome	18/483	162/7206	0.0364543799988
ko04114	Oocyte meiosis	16/483	139/7206	0.0369693571965
ko04745	Phototransduction - fly	6/483	38/7206	0.038919541904
ko04964	Proximal tubule bicarbonate reclamation	5/483	29/7206	0.0413406769801
ko04137	Mitophagy - animal	1/483	82/7206	0.0430044138479
ko04910	Insulin signaling pathway	5/483	172/7206	0.0435386286857
ko05161	Hepatitis B	5/483	173/7206	0.0437529361175
ko01200	Carbon metabolism	3/483	128/7206	0.047669010601
ko04978	Mineral absorption	6/483	40/7206	0.0484037333166
ko05323	Rheumatoid arthritis	11/483	89/7206	0.0497180761809