ko pathway ratio_in_study ratio_in_pop p_value ko05221 Acute myeloid leukemia 3/21 63/7206 0.000757096665429 ko05100 Bacterial invasion of epithelial cells 3/21 99/7206 0.0027953297375 ko04668 TNF signaling pathway 3/21 120/7206 0.00481211694113 ko04810 Regulation of actin cytoskeleton 4/21 264/7206 0.00643922257465 ko04380 Osteoclast differentiation 3/21 134/7206 0.00654453391723 ko04931 Insulin resistance 3/21 137/7206 0.00695831520723 ko05166 HTLV-I infection 4/21 292/7206 0.00915663750868 ko05160 Hepatitis C 3/21 153/7206 0.0094281463326 ko04071 Sphingolipid signaling pathway 3/21 162/7206 0.0110171016923 ko05200 Pathways in cancer 5/21 492/7206 0.0118528148511 ko04068 FoxO signaling pathway 3/21 167/7206 0.0119634358706 ko04910 Insulin signaling pathway 3/21 172/7206 0.0129557472933 ko05213 Endometrial cancer 2/21 62/7206 0.0137694654485 ko04210 Apoptosis 3/21 180/7206 0.0146400436902 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/21 182/7206 0.0150798327625 ko05223 Non-small cell lung cancer 2/21 66/7206 0.0155102396092 ko05167 Kaposi's sarcoma-associated herpesvirus infection 3/21 191/7206 0.017152272016 ko05130 Pathogenic Escherichia coli infection 2/21 77/7206 0.0207553043986 ko04730 Long-term depression 2/21 78/7206 0.0212643860215 ko05214 Glioma 2/21 79/7206 0.0217787044916 ko05131 Shigellosis 2/21 82/7206 0.0233527643073 ko05212 Pancreatic cancer 2/21 83/7206 0.023887714113 ko05220 Chronic myeloid leukemia 2/21 85/7206 0.0249728209446 ko05218 Melanoma 2/21 85/7206 0.0249728209446 ko04213 Longevity regulating pathway - multiple species 2/21 86/7206 0.0255229158758 ko05210 Colorectal cancer 2/21 86/7206 0.0255229158758 ko04920 Adipocytokine signaling pathway 2/21 89/7206 0.0272029967381 ko05211 Renal cell carcinoma 2/21 96/7206 0.0312930896188 ko04064 NF-kappa B signaling pathway 2/21 96/7206 0.0312930896188 ko04650 Natural killer cell mediated cytotoxicity 2/21 97/7206 0.0318963651 ko05132 Salmonella infection 2/21 98/7206 0.0325042955496 ko04620 Toll-like receptor signaling pathway 2/21 100/7206 0.0337340037827 ko04914 Progesterone-mediated oocyte maturation 2/21 104/7206 0.0362479931341 ko01521 EGFR tyrosine kinase inhibitor resistance 2/21 106/7206 0.0375318118981 ko04012 ErbB signaling pathway 2/21 109/7206 0.039490427114 ko05215 Prostate cancer 2/21 111/7206 0.0408177655498 ko05205 Proteoglycans in cancer 3/21 271/7206 0.0423998103722 ko04024 cAMP signaling pathway 3/21 279/7206 0.045597324189 ko04666 Fc gamma R-mediated phagocytosis 2/21 122/7206 0.0484163501882 ko04750 Inflammatory mediator regulation of TRP channels 2/21 122/7206 0.0484163501882 ko04211 Longevity regulating pathway 2/21 123/7206 0.0491313924035 ko04660 T cell receptor signaling pathway 2/21 124/7206 0.0498503618121 ko01522 Endocrine resistance 2/21 124/7206 0.0498503618121