ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 21/292 96/7206 1.41615478901e-10 ko00350 Tyrosine metabolism 9/292 33/7206 4.25706759583e-06 ko00230 Purine metabolism 21/292 194/7206 3.45301131177e-05 ko04260 Cardiac muscle contraction 14/292 98/7206 3.56643397197e-05 ko05200 Pathways in cancer 5/292 492/7206 7.31115014772e-05 ko04020 Calcium signaling pathway 25/292 265/7206 7.86780465708e-05 ko00140 Steroid hormone biosynthesis 8/292 41/7206 0.000196229924217 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/292 4/7206 0.000255601024614 ko00643 Styrene degradation 3/292 4/7206 0.000255601024614 ko04512 ECM-receptor interaction 11/292 79/7206 0.000309438340812 ko00360 Phenylalanine metabolism 5/292 17/7206 0.000437008558469 ko05410 Hypertrophic cardiomyopathy (HCM) 12/292 100/7206 0.000672791360079 ko04261 Adrenergic signaling in cardiomyocytes 19/292 205/7206 0.0007984181368 ko04976 Bile secretion 10/292 80/7206 0.00136276587377 ko04710 Circadian rhythm 7/292 43/7206 0.0015326660072 ko04972 Pancreatic secretion 12/292 111/7206 0.00169913112725 ko05414 Dilated cardiomyopathy 12/292 112/7206 0.00183575435025 ko05166 HTLV-I infection 3/292 292/7206 0.00359517877722 ko00250 Alanine, aspartate and glutamate metabolism 6/292 38/7206 0.00388379425185 ko04510 Focal adhesion 19/292 240/7206 0.00434960246863 ko04614 Renin-angiotensin system 4/292 18/7206 0.00515100587216 ko00950 Isoquinoline alkaloid biosynthesis 3/292 10/7206 0.00639189021258 ko05034 Alcoholism 2/292 238/7206 0.00645242662697 ko05168 Herpes simplex infection 1/292 182/7206 0.00714950589539 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/292 191/7206 0.0076307941849 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/292 11/7206 0.00852808805506 ko00100 Steroid biosynthesis 4/292 21/7206 0.00915663750869 ko05161 Hepatitis B 1/292 173/7206 0.0103659138365 ko04144 Endocytosis 5/292 342/7206 0.0104841459767 ko04921 Oxytocin signaling pathway 16/292 209/7206 0.01212805397 ko04975 Fat digestion and absorption 5/292 35/7206 0.0126319739769 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/292 79/7206 0.0142127915843 ko04152 AMPK signaling pathway 13/292 161/7206 0.0146376022889 ko00380 Tryptophan metabolism 6/292 50/7206 0.0149207672211 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/292 5/7206 0.0150877623875 ko04740 Olfactory transduction 8/292 80/7206 0.015255797811 ko05203 Viral carcinogenesis 4/292 277/7206 0.0191067329284 ko03320 PPAR signaling pathway 7/292 69/7206 0.0210374206141 ko00362 Benzoate degradation 2/292 6/7206 0.022030409794 ko00710 Carbon fixation in photosynthetic organisms 4/292 27/7206 0.0222080969421 ko04713 Circadian entrainment 11/292 136/7206 0.0252263133049 ko00830 Retinol metabolism 5/292 42/7206 0.0263364444144 ko03040 Spliceosome 1/292 145/7206 0.0313316747078 ko04270 Vascular smooth muscle contraction 12/292 154/7206 0.0343547233304 ko04022 cGMP-PKG signaling pathway 15/292 216/7206 0.0351407013051 ko04141 Protein processing in endoplasmic reticulum 2/292 184/7206 0.0351928755163 ko00270 Cysteine and methionine metabolism 5/292 47/7206 0.0403832589446 ko00401 Novobiocin biosynthesis 1/292 1/7206 0.0405217873995 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/292 1/7206 0.0405217873995 ko05231 Choline metabolism in cancer 1/292 134/7206 0.0449024322107 ko00120 Primary bile acid biosynthesis 3/292 20/7206 0.0450635279895 ko01210 2-Oxocarboxylic acid metabolism 3/292 20/7206 0.0450635279895 ko05224 Breast cancer 2/292 174/7206 0.0491853787349