ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 16/126 233/7206 2.5631837368e-06 ko04724 Glutamatergic synapse 12/126 152/7206 1.23523540167e-05 ko04727 GABAergic synapse 8/126 110/7206 0.000644835243507 ko05032 Morphine addiction 8/126 110/7206 0.000644835243507 ko04015 Rap1 signaling pathway 13/126 278/7206 0.0010871803939 ko04024 cAMP signaling pathway 13/126 279/7206 0.00112356104765 ko04010 MAPK signaling pathway 14/126 321/7206 0.00136948503368 ko04725 Cholinergic synapse 9/126 160/7206 0.00187901759353 ko04915 Estrogen signaling pathway 8/126 131/7206 0.00200682996391 ko04713 Circadian entrainment 8/126 136/7206 0.00253930285514 ko05206 MicroRNAs in cancer 9/126 177/7206 0.00372034369344 ko04742 Taste transduction 5/126 61/7206 0.00410738117754 ko01522 Endocrine resistance 7/126 124/7206 0.00587115197762 ko00513 Various types of N-glycan biosynthesis 4/126 42/7206 0.00597008907664 ko04072 Phospholipase D signaling pathway 9/126 197/7206 0.00744363965237 ko00515 Mannose type O-glycan biosynthesis 3/126 25/7206 0.00906523815874 ko04914 Progesterone-mediated oocyte maturation 6/126 104/7206 0.00954115637472 ko04261 Adrenergic signaling in cardiomyocytes 9/126 205/7206 0.0095511820391 ko01521 EGFR tyrosine kinase inhibitor resistance 6/126 106/7206 0.0104292329159 ko04723 Retrograde endocannabinoid signaling 8/126 175/7206 0.0113914691428 ko04371 Apelin signaling pathway 8/126 177/7206 0.012144030904 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 3/126 28/7206 0.0124310294891 ko04022 cGMP-PKG signaling pathway 9/126 216/7206 0.0131520783806 ko05230 Central carbon metabolism in cancer 5/126 81/7206 0.0134256165518 ko04728 Dopaminergic synapse 8/126 185/7206 0.0155247612149 ko05033 Nicotine addiction 4/126 56/7206 0.0162536164544 ko04213 Longevity regulating pathway - multiple species 5/126 86/7206 0.0170388933407 ko04144 Endocytosis 12/126 342/7206 0.0182174220344 ko04211 Longevity regulating pathway 6/126 123/7206 0.0204718439879 ko04722 Neurotrophin signaling pathway 7/126 160/7206 0.02177694942 ko04550 Signaling pathways regulating pluripotency of stem cells 7/126 165/7206 0.0252664392675 ko04020 Calcium signaling pathway 10/126 265/7206 0.025897848077 ko04720 Long-term potentiation 5/126 99/7206 0.0292964545988 ko05231 Choline metabolism in cancer 6/126 134/7206 0.029660894411 ko04973 Carbohydrate digestion and absorption 3/126 42/7206 0.0365359814391 ko05030 Cocaine addiction 4/126 73/7206 0.0384734731858 ko05014 Amyotrophic lateral sclerosis (ALS) 4/126 74/7206 0.0401408680582 ko04923 Regulation of lipolysis in adipocytes 4/126 77/7206 0.0453874079784