ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 24/179 191/7206 3.67879755848e-11 ko04380 Osteoclast differentiation 17/179 134/7206 2.74256893895e-08 ko04630 Jak-STAT signaling pathway 12/179 132/7206 9.9423520808e-05 ko04650 Natural killer cell mediated cytotoxicity 10/179 97/7206 0.000134870928996 ko05230 Central carbon metabolism in cancer 9/179 81/7206 0.000164865990706 ko05162 Measles 11/179 120/7206 0.000180704052191 ko04666 Fc gamma R-mediated phagocytosis 11/179 122/7206 0.000209278097643 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/179 191/7206 0.000267536030752 ko04659 Th17 cell differentiation 10/179 106/7206 0.000281736966928 ko05166 HTLV-I infection 18/179 292/7206 0.000319427164132 ko04610 Complement and coagulation cascades 8/179 79/7206 0.000718442656961 ko05231 Choline metabolism in cancer 10/179 134/7206 0.00177380445024 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/179 135/7206 0.00187532648985 ko04144 Endocytosis 18/179 342/7206 0.00215643323238 ko04014 Ras signaling pathway 16/179 279/7206 0.00227044465203 ko04664 Fc epsilon RI signaling pathway 7/179 77/7206 0.00288544520409 ko04668 TNF signaling pathway 9/179 120/7206 0.00288861102295 ko04072 Phospholipase D signaling pathway 12/179 197/7206 0.00356359802822 ko04062 Chemokine signaling pathway 12/179 201/7206 0.00419173456395 ko05212 Pancreatic cancer 7/179 83/7206 0.00439975412939 ko04662 B cell receptor signaling pathway 7/179 88/7206 0.00606688845595 ko05200 Pathways in cancer 22/179 492/7206 0.00634804926703 ko04931 Insulin resistance 9/179 137/7206 0.0069136927199 ko04068 FoxO signaling pathway 10/179 167/7206 0.00852417367512 ko04919 Thyroid hormone signaling pathway 9/179 143/7206 0.00906602126402 ko04658 Th1 and Th2 cell differentiation 7/179 96/7206 0.00965886005494 ko04015 Rap1 signaling pathway 14/179 278/7206 0.00993585477414 ko04910 Insulin signaling pathway 10/179 172/7206 0.0103834186478 ko05140 Leishmaniasis 6/179 75/7206 0.0105497926707 ko05418 Fluid shear stress and atherosclerosis 10/179 173/7206 0.010789748404 ko04066 HIF-1 signaling pathway 8/179 123/7206 0.011287761026 ko05321 Inflammatory bowel disease (IBD) 5/179 56/7206 0.0122825814426 ko04672 Intestinal immune network for IgA production 4/179 37/7206 0.0128311637011 ko05214 Glioma 6/179 79/7206 0.0134312363217 ko04960 Aldosterone-regulated sodium reabsorption 4/179 41/7206 0.0182276605068 ko05213 Endometrial cancer 5/179 62/7206 0.018483137971 ko05169 Epstein-Barr virus infection 11/179 206/7206 0.0185977202115 ko05218 Melanoma 6/179 85/7206 0.0187232318208 ko05220 Chronic myeloid leukemia 6/179 85/7206 0.0187232318208 ko04611 Platelet activation 9/179 163/7206 0.0199929600125 ko05215 Prostate cancer 7/179 111/7206 0.0202297049471 ko04917 Prolactin signaling pathway 6/179 87/7206 0.0207650196028 ko04710 Circadian rhythm 4/179 43/7206 0.0213824148683 ko04550 Signaling pathways regulating pluripotency of stem cells 9/179 165/7206 0.0214579818525 ko05202 Transcriptional misregulation in cancer 10/179 188/7206 0.0267397372684 ko04064 NF-kappa B signaling pathway 6/179 96/7206 0.0318183960892 ko05164 Influenza A 9/179 167/7206 0.0372557589151 ko05340 Primary immunodeficiency 3/179 30/7206 0.0374416643318 ko04620 Toll-like receptor signaling pathway 6/179 100/7206 0.0377671630767 ko04930 Type II diabetes mellitus 4/179 54/7206 0.0444928755374 ko05168 Herpes simplex infection 9/179 182/7206 0.0468458834649 ko01521 EGFR tyrosine kinase inhibitor resistance 6/179 106/7206 0.0479496837609 ko04360 Axon guidance 11/179 233/7206 0.0486789125238 ko00254 Aflatoxin biosynthesis 1/179 2/7206 0.0490671375523 ko00073 Cutin, suberine and wax biosynthesis 1/179 2/7206 0.0490671375523