ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 27/225 145/7206 2.98728855296e-14 ko03030 DNA replication 15/225 38/7206 1.34484560461e-13 ko04110 Cell cycle 26/225 145/7206 2.35391425663e-13 ko05322 Systemic lupus erythematosus 23/225 151/7206 1.96627280846e-10 ko03008 Ribosome biogenesis in eukaryotes 17/225 79/7206 2.00026591703e-10 ko03410 Base excision repair 12/225 38/7206 8.4733505182e-10 ko05034 Alcoholism 24/225 238/7206 3.181291298e-07 ko00240 Pyrimidine metabolism 15/225 110/7206 1.38384991544e-06 ko05203 Viral carcinogenesis 25/225 277/7206 1.45385430896e-06 ko03015 mRNA surveillance pathway 12/225 93/7206 2.85358199495e-05 ko04111 Cell cycle - yeast 11/225 90/7206 0.000102092910569 ko03050 Proteasome 8/225 54/7206 0.000240192130885 ko04144 Endocytosis 1/225 342/7206 0.000341585741846 ko03430 Mismatch repair 5/225 22/7206 0.000483872005632 ko03420 Nucleotide excision repair 7/225 46/7206 0.000499379346247 ko03013 RNA transport 14/225 166/7206 0.000654211004048 ko04218 Cellular senescence 14/225 177/7206 0.00122935925343 ko04113 Meiosis - yeast 8/225 70/7206 0.00142012458834 ko05169 Epstein-Barr virus infection 15/225 206/7206 0.00190823090786 ko05202 Transcriptional misregulation in cancer 14/225 188/7206 0.00217967203177 ko00230 Purine metabolism 13/225 194/7206 0.00950261901264 ko04612 Antigen processing and presentation 7/225 77/7206 0.0099284239958 ko03450 Non-homologous end-joining 3/225 15/7206 0.0103509375952 ko04330 Notch signaling pathway 6/225 62/7206 0.0124090170132 ko04024 cAMP signaling pathway 2/225 279/7206 0.0127034274803 ko01522 Endocrine resistance 9/225 124/7206 0.0152518373194 ko04022 cGMP-PKG signaling pathway 1/225 216/7206 0.0153134709561 ko04810 Regulation of actin cytoskeleton 2/225 264/7206 0.0178463175756 ko04072 Phospholipase D signaling pathway 1/225 197/7206 0.0218751315177 ko04062 Chemokine signaling pathway 1/225 201/7206 0.0219421615649 ko04921 Oxytocin signaling pathway 1/225 209/7206 0.0231037389229 ko05224 Breast cancer 11/225 174/7206 0.0238092911016 ko05166 HTLV-I infection 16/225 292/7206 0.0247040855732 ko04115 p53 signaling pathway 6/225 74/7206 0.0275272693177 ko04723 Retrograde endocannabinoid signaling 1/225 175/7206 0.0454216466601 ko04371 Apelin signaling pathway 1/225 177/7206 0.0457244623236 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/225 182/7206 0.0471752510332