ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	28/579	56/7206	1.0494758946e-16
ko04728	Dopaminergic synapse	46/579	185/7206	1.54237756146e-12
ko04721	Synaptic vesicle cycle	26/579	80/7206	2.39744619135e-10
ko04724	Glutamatergic synapse	37/579	152/7206	4.92335913079e-10
ko04080	Neuroactive ligand-receptor interaction	71/579	423/7206	9.47232872591e-10
ko04727	GABAergic synapse	29/579	110/7206	5.48956397853e-09
ko04723	Retrograde endocannabinoid signaling	37/579	175/7206	3.03197946118e-08
ko04360	Axon guidance	44/579	233/7206	5.54494954356e-08
ko04713	Circadian entrainment	31/579	136/7206	6.74288097074e-08
ko05032	Morphine addiction	27/579	110/7206	9.49900089808e-08
ko05030	Cocaine addiction	20/579	73/7206	6.79363129925e-07
ko04024	cAMP signaling pathway	46/579	279/7206	2.48788632551e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	19/579	74/7206	3.75188455056e-06
ko04911	Insulin secretion	25/579	117/7206	4.46530105098e-06
ko04950	Maturity onset diabetes of the young	11/579	29/7206	7.42684694625e-06
ko04725	Cholinergic synapse	30/579	160/7206	9.84318641663e-06
ko05031	Amphetamine addiction	20/579	91/7206	2.6066541817e-05
ko04010	MAPK signaling pathway	47/579	321/7206	5.1524871303e-05
ko04726	Serotonergic synapse	25/579	137/7206	8.57119150168e-05
ko04261	Adrenergic signaling in cardiomyocytes	33/579	205/7206	0.000113226875858
ko03040	Spliceosome	1/579	145/7206	0.00014018571007
ko04060	Cytokine-cytokine receptor interaction	3/579	191/7206	0.000202036977438
ko04514	Cell adhesion molecules (CAMs)	23/579	130/7206	0.000253806555485
ko01200	Carbon metabolism	1/579	128/7206	0.000434415911746
ko05224	Breast cancer	27/579	174/7206	0.000934455285491
ko04611	Platelet activation	3/579	163/7206	0.00114960230657
ko03013	RNA transport	3/579	166/7206	0.00120534448576
ko04120	Ubiquitin mediated proteolysis	2/579	138/7206	0.00132844678679
ko04512	ECM-receptor interaction	15/579	79/7206	0.00134256370724
ko04151	PI3K-Akt signaling pathway	49/579	390/7206	0.00146693578047
ko04340	Hedgehog signaling pathway	12/579	58/7206	0.00186201280548
ko05322	Systemic lupus erythematosus	3/579	151/7206	0.00230189978062
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/579	14/7206	0.0035728546593
ko04974	Protein digestion and absorption	16/579	96/7206	0.00412064479763
ko05203	Viral carcinogenesis	10/579	277/7206	0.00447122633424
ko04550	Signaling pathways regulating pluripotency of stem cells	23/579	165/7206	0.00843114630907
ko04742	Taste transduction	11/579	61/7206	0.00848492309234
ko05217	Basal cell carcinoma	12/579	68/7206	0.0105500808005
ko05168	Herpes simplex infection	6/579	182/7206	0.0125734409745
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/579	182/7206	0.0125734409745
ko04145	Phagosome	22/579	162/7206	0.0126267095988
ko04141	Protein processing in endoplasmic reticulum	6/579	184/7206	0.0126596730123
ko03018	RNA degradation	1/579	84/7206	0.0137022163758
ko05162	Measles	3/579	120/7206	0.0174747167102
ko04923	Regulation of lipolysis in adipocytes	1/579	77/7206	0.0196998306751
ko03008	Ribosome biogenesis in eukaryotes	1/579	79/7206	0.0199416361326
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/579	8/7206	0.0212779604431
ko00430	Taurine and hypotaurine metabolism	4/579	14/7206	0.0215460910303
ko04064	NF-kappa B signaling pathway	2/579	96/7206	0.0229489859379
ko00564	Glycerophospholipid metabolism	2/579	99/7206	0.0233698076592
ko04621	NOD-like receptor signaling pathway	5/579	157/7206	0.0243450019606
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/579	59/7206	0.0249857462074
ko05200	Pathways in cancer	53/579	492/7206	0.0251675279656
ko04964	Proximal tubule bicarbonate reclamation	6/579	29/7206	0.0252973896012
ko02024	Quorum sensing	4/579	15/7206	0.0275592827114
ko00310	Lysine degradation	1/579	73/7206	0.0286930372886
ko00010	Glycolysis / Gluconeogenesis	1/579	74/7206	0.0289706008963
ko05164	Influenza A	6/579	167/7206	0.0298929750219
ko04330	Notch signaling pathway	10/579	62/7206	0.0302565493422
ko04391	Hippo signaling pathway - fly	13/579	90/7206	0.031400674953
ko00240	Pyrimidine metabolism	3/579	110/7206	0.0334573776995
ko04976	Bile secretion	12/579	80/7206	0.0346433356123
ko04260	Cardiac muscle contraction	14/579	98/7206	0.0362046125884
ko04720	Long-term potentiation	14/579	99/7206	0.0374126682533
ko04978	Mineral absorption	7/579	40/7206	0.0379703196867
ko04014	Ras signaling pathway	32/579	279/7206	0.0420707575134
ko04146	Peroxisome	2/579	89/7206	0.0465188140355
ko04962	Vasopressin-regulated water reabsorption	9/579	58/7206	0.0479420706635