Selected Publications
03. Wen Chen, Jing Li, Shulan Huang, Xiaodeng Li, Xuan Zhan, Xiang Hu, Shuanglin Xiang*, Changning Liu*. GCEN: An Easy-to-Use Toolkit for Gene Co-Expression Network Analysis and lncRNAs Annotation. Current Issues in Molecular Biology 2022; 44(4): 1479-1487.
02. Wen Chen#, Guoqiang Zhang#, Jing Li#, Xuan Zhang, Shulan Huang, Shuanglin Xiang, Xiang Hu*, Changning Liu*. CRISPRlnc: a manually curated database of validated sgRNAs for lncRNAs. Nucleic Acids Research 2019; 47(D1):D63-D68.
01. Wen Chen#, Xuan Zhang#, Jing Li#, Shulan Huang, Shuanglin Xiang, Xiang Hu*, Changning Liu*. Comprehensive analysis of coding-lncRNA gene co-expression network uncovers conserved functional lncRNAs in zebrafish. BMC Genomics 2018; 19(Suppl 2):112.
# Co-first author, * Corresponding author.
Full list of publications
20. Zitian Yang, Zexin Zhang, Jing Li, Wen Chen, Changning Liu*. CRISPRlnc: a machine learning method for lncRNA-specific single-guide RNA design of CRISPR/Cas9 system. Briefings in Bioinformatics 2024; 25(2):bbae066.
19. Quanye Luo#,Yu Wei#, Xuzhen Lv, Wen Chen, Dongmei Yang*, Qinhui Tuo*. The Effect and Mechanism of Oleanolic Acid in the Treatment of Metabolic Syndrome and Related Cardiovascular Diseases. Molecules 2024; 29(4):758.
18. Bo Hu, Wen Chen, Yancheng Zhong*, Qinhui Tuo*. The role of lncRNA-mediated pyroptosis in cardiovascular diseases. Frontiers in Cardiovascular Medicine 2023; 10:1217985.
17. Jiazhi Liu, Yan Li, Jing Li, Wen Chen, Bangzhen Pan, Aizhong Liu, Zeng-Fu Xu, Wei Xu*, Changning Liu*. EupDB: An integrative and comprehensive functional genomics data hub for Euphorbiaceae plants. Plant Communications 2024; 5(1):100683.
16. Shulan Huang, Hongning Zhang, Wen Chen, Jiawei Wang, Zhen Wu, Meiqi He, Jian Zhang, Xiang Hu*, Shuanglin Xiang*. Screening of Tnfaip1-Interacting Proteins in Zebrafish Embryonic cDNA Libraries Using a Yeast Two-Hybrid System. Current Issues in Molecular Biology 2023; 45(10), 8215-8226.
15. Minyu Zhou#, Lian Xu#, Dahua Xu#, Wen Chen#, Jehangir Khan, Yue Hu, Hui Huang, Hang Wei, Yiqing Zhang, Phiraphol Chusongsang, Kanthi Tanasarnprasert, Xiang Hu*, Yanin Limpanont*, Zhiyue Lv*. Chromosome-scale genome of the human blood fluke Schistosoma mekongi and its implications for public health. Infectious Diseases of Poverty 2023; 12:104.
14. Shulan Huang, Hongning Zhang, Wen Chen, Na Su, Changyue Yuan, Jian Zhang, Shuanglin Xiang*, Xiang Hu*. CRISPR/Cas9-Mediated Knockout of tnfaip1 in Zebrafish Plays a Role in Early Development. Genes 2023; 14(5):1005.
13. Wen Chen, Jing Li, Shulan Huang, Xiaodeng Li, Xuan Zhan, Xiang Hu, Shuanglin Xiang*, Changning Liu*. GCEN: An Easy-to-Use Toolkit for Gene Co-Expression Network Analysis and lncRNAs Annotation. Current Issues in Molecular Biology 2022; 44(4): 1479-1487.
12. Shiye Sang, Wen Chen, Di Zhang, Xuan Zhan, Wenjing Yang, Changning Liu*. Data integration and evolutionary analysis of long non-coding RNAs in 25 flowering plants. BMC Genomics 2021; 22(Suppl 3):739.
11. Xuan Zhang, Jing Li, Bang-Zhen Pan, Wen Chen, Maosheng Chen, Mingyong Tang, Zeng-Fu Xu*, Changning Liu*. Extended mining of the oil biosynthesis pathway in biofuel plant Jatropha curcas by combined analysis of transcriptome and gene interactome data. BMC Bioinformatics 2021; 22(6): 409.
10. Xiaoyang Gao#, Xuan Zhang#, Wen Chen#, Jing Li, Wenjing Yang, Xingwang Zhang, Shengying Li, Changning Liu*. Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves. Phytochemistry 2020; 178:112460.
09. Jun Wang#, Xuan Zhang#, Wen Chen#, Xiang Hu, Jing Li*, Changning Liu*. Regulatory roles of long non-coding RNAs implicated in cancer hallmarks. International Journal of Cancer 2020; 146(4):906-916.
08. Ye Xiao, Shulan Huang, Feng Qiu, Xiaofeng Ding,Yi Sun, Chenxi Wei, Xiang Hu, Ke Wei, Shengwen Long, Lina Xie, Yu Xun, Wen Chen, Zhijian Zhang, Ning Liu*, Shuanglin Xiang*. Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma. EBioMedicine 2020; 51:102603.
07. Xuan Zhang#, Bang-Zhen Pan#, Maosheng Chen, Wen Chen, Jing Li, Zeng-Fu Xu*, Changning Liu*. JCDB: a comprehensive knowledge base for Jatropha curcas, an emerging model for woody energy plants. BMC Genomics 2019; 20(Suppl 9):958.
06. Wen Chen#, Guoqiang Zhang#, Jing Li#, Xuan Zhang, Shulan Huang, Shuanglin Xiang, Xiang Hu*, Changning Liu*. CRISPRlnc: a manually curated database of validated sgRNAs for lncRNAs. Nucleic Acids Research 2019; 47(D1):D63-D68.
05. Xuan Zhang#, Jun Wang#, Jing Li#, Wen Chen, Changning Liu*. CRlncRC: a novel machine learning method for cancer-related long noncoding RNA identification based on integrated features. BMC Medical Genomics 2018; 11(Suppl 6):120.
04. Jun Wang#, Xuan Zhang#, Wen Chen#, Jing Li*, Changning Liu*. CRlncRNA: a manually curated database of cancer-related long non-coding RNAs with experimental proof of functions on clinicopathological and molecular features. BMC Medical Genomics 2018; 11(Suppl 6):114.
03. Xiang Hu#, Wen Chen#, Jing Li#, Shulan Huang, Xuling Xu, Xuan Zhang, Shuanglin Xiang*, Changning Liu*. ZFLNC: a comprehensive and well annotated database for zebrafish lncRNA. Database 2018; 2018:bay114
02. Wen Chen#, Xuan Zhang#, Jing Li#, Shulan Huang, Shuanglin Xiang, Xiang Hu*, Changning Liu*. Comprehensive analysis of coding-lncRNA gene co-expression network uncovers conserved functional lncRNAs in zebrafish. BMC Genomics 2018; 19(Suppl 2):112.
01. Shang Wang#, Wen Chen#, Kai Zhang#, Peng Jiao, Lihua Mo, Xiaoxu Yang, Xiang Hu, Jian Zhang, Chenxi Wei*, Shuanglin Xiang*. Restriction-based Multiple-fragment Assembly Strategy to Avoid Random Mutation during Long cDNA Cloning. Journal of Cancer 2015; 6(7):632-635.